Method for Modulating the Immune System Using Adjuvant-Loaded Nanoparticle-Bacteria Constructs
Invention type: Technology
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Case number: #16067J
Provided herein are new compositions including an inactivated pathogen and one or more adjuvant-loaded polymeric nanoparticles, wherein the adjuvant-loaded nanoparticles are bound to the inactivated pathogen. These compositions are useful for preventing and/or treating diseases caused by the specific pathogens, especially when administered to a subject's mucosal membranes.
Researchers
Robert Langer
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Georg Stary
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Ulrich Von Andrian
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Pamela Basto
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Aleksandar Radovic-Moreno
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Michael Starnbach
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Omid Farokhzad
Departments: Office of the Institute Professors
Technology Areas: Biotechnology: Synthetic Biology / Chemicals & Materials: Composites, Nanotechnology & Nanomaterials / Drug Delivery: Microparticles & Nanoparticles
Impact Areas: Healthy Living
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nanoparticle-based compositions
United States of America | Granted | 10,485,861
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