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Applications of Streptococcus-derived Cas9 Nucleases on Minimal A-Rich PAM Targets

Technology / Case number: #20491XTE
Joseph Jacobson / Pranam Chatterjee / Lisa Nip / Noah Jakimo
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Full-field Optical Coherence Microscopy System Using a Digital Focal Plane Array

Technology / Case number: #24144LJ
Guillermo Tearney / Michael Bradshaw / Osman Ahsen / Matthew Johnson / Joseph Gardecki
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living, Advanced Materials
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Fast Nonlinear Dynamic Electrochemical Characterization of Arbitrary Fluids

Technology / Case number: #24656
Ian Hunter / Billal Iqbal / Kimberley Cheng / Michael Aling
Technology Areas: Agriculture & Food / Biotechnology / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
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Anti-Ebola Neutralizing Antibodies

Technology / Case number: #17334
Ram Sasisekharan / Devin Quinlan / Vidya Subramanian / Kannan Tharakaraman
Technology Areas: Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Boron-Containing Pharmacophore

Technology / Case number: #21111
Ronald T Raines / Brian Graham / Ian Windsor
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Methods of Breeding, Maintaining, and Releasing Wild-Like Organisms with Desired Genetics

Technology / Case number: #20965TEJ
Kevin Esvelt / Sam Telford III
Technology Areas: Drug Discovery and Research Tools
Impact Areas: Sustainable Future
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Novel Short Tandem Repeats (STRs) Analysis Methods

Technology / Case number: #18500L
James Harper / James Watkins / Philip Fremont-Smith / Adam Michaleas / Joseph Isaacson / Darrell Ricke / Brian Helfer / Anna Shcherbina / Edward Wack / Eric Schwoebel / Martha Petrovick
Technology Areas: Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Single-Step Insertion into Repeated Regions for Efficient Multi-Locus Assortment and Daisyfield Drive

Technology / Case number: #19136TJE
Kevin Esvelt / Charleston Noble / Jianghong Min
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living, Uncharted Frontiers
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Synthetic Hydrogels for Stem Cell Propagation and Organogenesis

Technology / Case number: #20047
Linda Griffith
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
Labels
  • Women's Health
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Implantable piezoelectric ultrasound stimulator (ImPULS)

Technology / Case number: #25217TE
Canan Dagdeviren / Md Osman Goni Nayeem / Jason Hou
Technology Areas: Diagnostics / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
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Two Person Mixture Deconvolution for Application with ForenSeq Kintelligence Workflow

Technology / Case number: #24078L
Philip Fremont-Smith / Natalie Damaso / Chelsea Lennartz
Technology Areas: Chemicals & Materials / Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Optimized Opsin Trafficking with Fluorescence-Dead Protein Fusions

Technology / Case number: #18783TE
Edward Stuart Boyden / Demian Park / Aimei Yang / Kiryl Piatkevich
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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A Dynamic Single-Cell Fragility Test that Assesses Red Blood Cell Membrane Integrity with Applications to Stored Blood

Technology / Case number: #25732J
Subra Suresh / Fang Kong / Ming Dao
Technology Areas: Diagnostics / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Frameshift Suppressor tRNAs for Canonical Amino Acids

Technology / Case number: #21418TREJ
Kevin Esvelt / Ahmed Badran / Erika Alden DeBenedictis
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Advanced Materials
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Method to Pattern Cells (Crude Blood) on a (Planar) Surface

Technology / Case number: #15262
Shivang Dave / German Serrano
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Daughterless Male Mammals for Population Suppression

Technology / Case number: #21866TE
Kevin Esvelt
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Sustainable Future
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Long-term Stabilization, Formulation and Tableting of Live Microbial Cells

Technology / Case number: #22886J
Robert Langer / Emily Kolaya / Johanna L'Heureux / Miguel Jimenez / Giovanni Traverso
Technology Areas: Drug Discovery and Research Tools
Impact Areas: Healthy Living
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In Vitro Human Blood Brain Barrier

Technology / Case number: #19918P
Li-Huei Tsai / Joel Blanchard
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Methods for the Treatment of Trinucleotide Repeat Expansion Disorders Associated with FAN1 activity via Targeting of FAN1 Splice Site Inhibitory Sequences

Technology / Case number: #24829
David Housman / Christopher Ng
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Methods for Improving Cross-Ancestry Transferability in Predicting Polygenic Phenotypes from Genetic Variation

Technology / Case number: #24858
Manolis Kellis / Yosuke Tanigawa
Technology Areas: Drug Discovery and Research Tools
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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