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Development of Multi-Specific Antibody-Serum Albumin Fusion Proteins Targeting Multiple Human and Murine CXC (ELR+) Chemokines

Technology / Case number: #19355JQ
Karl Dane Wittrup / Andrew Luster / Alessandro Angelini
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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A Biomedical Imaging and Optical Stimulation Device

Technology / Case number: #18022
Juejun Hu / Qi Qin / Tian Gu
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living
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Discovery of Self-Labeling Miniproteins

Technology / Case number: #18742
Bradley L. Pentelute / Ethan Evans
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Uncharted Frontiers, Advanced Materials
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METRAN - Software for 13C-metabolic Flux Analysis

Software / Case number: #12397
Technology Areas: Biotechnology / Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living, Connected World
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Structured DNA Conjugates

Technology / Case number: #18588
Mark Bathe / Hyungmin Jun / Tyson Shepherd / Remi Veneziano / Sakul Ratanalert
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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High Molecular Weight, Post-Translationally Modified Proteins Brushes Through Tyrosine Modification Chemistry

Technology / Case number: #17927
Bradley D. Olsen / Brian Seifried
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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New Methods to Assess Fluid Distribution in Muscle Tissue via Single Sided Magnetic Resonance Sensors

Technology / Case number: #21335
Michael Cima / Christopher Frangieh / Ashvin Bashyam
Technology Areas: Biotechnology / Diagnostics
Impact Areas: Healthy Living
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Intracellular Calcium Sensors for MRI

Technology / Case number: #20143
Alan Pradip Jasanoff / Benjamin Bartelle / Ali Barandov
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living, Uncharted Frontiers
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Highly Parallel Enzymatic DNA Synthesis Using Electrowetting Droplet Technology

Technology / Case number: #19620
Mark Bathe / Joseph Berleant / James Banal / Tyson Shepherd
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Methods for Gene Delivery with Papillomaviruses

Technology / Case number: #21704
Omar Abudayyeh / Jonathan S. Gootenberg
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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Compounds, Targets and Pathways for Macrophage Modulation

Technology / Case number: #22081
Jianzhu Chen / Guangan Hu
Technology Areas: Diagnostics
Impact Areas: Healthy Living
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Novel Peptidic Agents for Targeting Chemoresistant Anti-Apoptotic Mcl-1

Technology / Case number: #17695J
Amy Keating / Loren Walensky / Greg Bird / Raheleh Rezaei Araghi
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers, Advanced Materials
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Nitroxide-Based Macromolecular Contrast Agents with Unprecedented Transverse Relaxivity and Stability for Magnetic Resonance Imaging of Tumors

Technology / Case number: #19540J
Jeremiah A. Johnson / Andrzej Rajca / Hung Nguyen
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living
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Removal of Ruthenium-Initiator from Brush-Arm Star Polymers (BASPs) via Core-to-Surface Ring-Opening Methathesis Polymerization (ROMP)

Technology / Case number: #19525
Jeremiah A. Johnson / Matthew Golder
Technology Areas: Biotechnology / Drug Delivery / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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GLYCAN-BINDING PROTEINS AND RELATED COMPOSITIONS AND METHODS

Technology / Case number: #21107
Barbara Imperiali / Elizabeth Ward / Cristina Cella
Technology Areas: Diagnostics / Therapeutics
Impact Areas: Healthy Living
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Magnetic Nanodiscs Mediate Remote Magnetomechanical Control of Neural Calcium

Technology / Case number: #20085
Polina Anikeeva / Pooja Reddy / Danijela Gregurec / Alexander Senko
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools
Impact Areas: Healthy Living, Advanced Materials
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Streptococcus Canis Cas9 for Tunable Genome Engineering and Regulation

Technology / Case number: #19757XTE
Joseph Jacobson / Pranam Chatterjee / Noah Jakimo
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living, Uncharted Frontiers, Sustainable Future
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RNA-Based Regulatory Technologies for Improved miRNA Sensors

Technology / Case number: #19686
Ron Weiss / Jin Huh / Kevin Lebo
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Novel Peptidic Agents for Targeting Chemoresistant Anti-Apoptotic Bfl-1

Technology / Case number: #18607
Amy Keating / Justin Jenson
Technology Areas: Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
License

Methods and Systems for Raman Spectroscopy Based Detection of Blood Analytes in the Tympanic Membrane Vasculature

Technology / Case number: #17459
Ramachandra Dasari / Nicolas Spegazzini / Tulio Valdez / Rishikesh Pandey / Luis Galindo
Technology Areas: Biotechnology / Diagnostics
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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