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Genomic Insertion of Large Cargo with Engineered Retro Elements

Technology / Case number: #23248
Omar Abudayyeh / Justin Lim / Lukas Villiger / Jonathan S. Gootenberg
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Ligand-Inducible Post-Transcriptional Gene Regulation Using Protein-Binding RNA Aptamers

Technology / Case number: #13998J
Brian Belmont / Michael Marletta / Jacquin Niles / Stephen Goldfless
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Tissue Specific Delivery of Interfering RNA

Technology / Case number: #13947H
Sangeeta Bhatia / Yin Ren
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Peptide Nucleic Acid Functionalized Hydrogel Microneedles for Sampling and Detection of Interstitial Fluid Nucleic Acids

Technology / Case number: #21359HJ
Darrell J Irvine / Dana Al Sulaiman / Sylvain Ladame / Yin Hao Chang
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Anti-Ebola Neutralizing Antibodies

Technology / Case number: #17334
Ram Sasisekharan / Devin Quinlan / Vidya Subramanian / Kannan Tharakaraman
Technology Areas: Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Robocap

Technology / Case number: #24836J
Robert Langer / Amro Alshareef / Shriya Sruthi Srinivasan / Giovanni Traverso
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Boron-Containing Pharmacophore

Technology / Case number: #21111
Ronald T Raines / Brian Graham / Ian Windsor
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Production of Stable Non-Polyadenylated RNAs

Technology / Case number: #15860
Phillip Sharp / Jeremy Wilusz
Technology Areas: Biotechnology / Drug Delivery
Impact Areas: Healthy Living
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Methods of Breeding, Maintaining, and Releasing Wild-Like Organisms with Desired Genetics

Technology / Case number: #20965TEJ
Kevin Esvelt / Sam Telford III
Technology Areas: Drug Discovery and Research Tools
Impact Areas: Sustainable Future
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Compact, Portable, Re-Configurable Unit for Making On-Demand Pharmaceutical Tablets

Technology / Case number: #19221
David Brancazio / Gregory Hammersmith / Juan Osorio Caicedo / Mohammad Azad / Allan S. Myerson
Technology Areas: Drug Delivery / Industrial Engineering & Automation
Impact Areas: Healthy Living
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Novel Short Tandem Repeats (STRs) Analysis Methods

Technology / Case number: #18500L
James Harper / James Watkins / Philip Fremont-Smith / Adam Michaleas / Joseph Isaacson / Darrell Ricke / Brian Helfer / Anna Shcherbina / Edward Wack / Eric Schwoebel / Martha Petrovick
Technology Areas: Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Single-Step Insertion into Repeated Regions for Efficient Multi-Locus Assortment and Daisyfield Drive

Technology / Case number: #19136TJE
Kevin Esvelt / Charleston Noble / Jianghong Min
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living, Uncharted Frontiers
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Synthetic Hydrogels for Stem Cell Propagation and Organogenesis

Technology / Case number: #20047
Linda Griffith
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
Labels
  • Women's Health
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Conformable Ultrasound Face Patch for Cavitation Enhanced Transdermal

Technology / Case number: #24824TE
Canan Dagdeviren
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
License

Ionizable Lipid OF-02 and its Use in mRNA Delivery

Technology / Case number: #17733
Daniel Anderson / Rebecca McClellan / Kevin Kauffman / Owen Fenton / Joseph Dorkin
Technology Areas: Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living, Advanced Materials
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Two Person Mixture Deconvolution for Application with ForenSeq Kintelligence Workflow

Technology / Case number: #24078L
Philip Fremont-Smith / Natalie Damaso / Chelsea Lennartz
Technology Areas: Chemicals & Materials / Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Human Microbiome Clostridia-Derived Biosynthetic Enzymes/Pathways for the Biological Production of Natural and Non-Natural Fatty Acylated Compounds

Technology / Case number: #20961
Christopher Voigt / Fang-Yuan Chang
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living
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In Vitro and in Vivo Delivery of Complex Genetic Circuits up to 33kb Using Engineered HSV-1

Technology / Case number: #20746
Ron Weiss / Ross Jones / Jin Huh / Maria Hottelet Foley
Technology Areas: Diagnostics / Drug Delivery
Impact Areas: Healthy Living
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Optimized Opsin Trafficking with Fluorescence-Dead Protein Fusions

Technology / Case number: #18783TE
Edward Stuart Boyden / Demian Park / Aimei Yang / Kiryl Piatkevich
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
License

Oligomeric Conjugates for siRNA Delivery and Glucose-Responsive Insulins

Technology / Case number: #15977J
Robert Langer / Rosemary Kanasty / Arturo Vegas / Daniel Anderson
Technology Areas: Diagnostics / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
License

The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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