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Multiplexed Expansion Revealing

Technology / Case number: #24562MH
Edward Boyden / Jinyoung Kang / Margaret Schroeder
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
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Constriction-Minimizing Microfluidic Devices Enabling Co-Culture in Engineered Hydrogels

Technology / Case number: #24723P
Li-Huei Tsai / Robert Langer / Alice Stanton
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Scalable Sets of Protein Barcodes for Neural Morphology Measurement and Connectomics

Technology / Case number: #24825MH
Edward Boyden / Samuel Rodriques / Andrew Payne / Bobae An
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
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A Fabrication-Free Microfluidic Device for Scalable, High-Volume Bacterial Electroporation

Technology / Case number: #23552
Cullen Buie / Po-Hsun Huang / Sijie Chen
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Intracellular Molecular Recording and Memory via Protein Self-Assembly

Technology / Case number: #23746HPM
Edward Boyden / Changyang Linghu
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Autocatalytic Base Editing for RNA-Responsive Translational Control

Technology / Case number: #24552YJ
James Collins / Raphael Gayet / Katherine Ilia / Shiva Razavi / Nathaniel Tippens / Kehan Zhang / Xiaoyu Chen / Jonathan Chen / Makoto Lalwani
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Temporally Multiplexed Imaging Technology

Technology / Case number: #24554MH
Edward Boyden / Yong Qian
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
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An Endoribonuclease-based Incoherent Feedforward Loop for Accurate Control of Gene Expression Levels in Mammalian Cells

Technology / Case number: #21843
Ron Weiss / Ross Jones / Breanna DiAndreth / Domitilla Del Vecchio / Yili Qian
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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High-Throughput Expansion Microscopy

Technology / Case number: #22339
Laurie Boyer / Edward Boyden / Pema Maretich / Alexander Auld / John Day / Catherine Della Santina
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
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Endogenous Gene Sensing and Actuation by Placement of Non-Coding RNA after Transcriptional Termination Signals

Technology / Case number: #21520
James Collins / Ron Weiss / Jeremy Gam / Elvira Vitu / Casper Enghuus
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Characterization and Utilization of a Subgenomic Promoter Mutant Library for Tuning Expression of Multiple Transgenes from Alphavirus Replicons

Technology / Case number: #21309
Ron Weiss / Jin Huh
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Optimization of Circular Single Stranded DNA using M13 Phage

Technology / Case number: #21211
Christopher Voigt / Uyanga Tsedev / Tae-Gon Cha / Angela Belcher
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Novel Chimeric Antigen Receptor Signaling Domains Derived via Activity-based Directed Evolution

Technology / Case number: #21116
Michael Birnbaum / Taeyoon Kyung
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Redox-Electrodes for Electrochemically-Controlled Bio-Macromolecule Interaction: Bio-Separations, Heterogeneous Enzyme Immobilization, Protein Purification and Sensing, Among Others

Technology / Case number: #18540
Trevor Hatton / Xiao Su
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Environmental Engineering
Impact Areas: Sustainable Future, Advanced Materials
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TRAV-005 (Needles) 62/795,857

Technology / Case number: #22144J
Selim Olcum / Robert Kimmerling / David Weinstock / Scott Manalis
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Fully Efficient LED Therapy Mask

Technology / Case number: #20825
Jeehwan Kim / Hanwool Yeun / Da Hye Park
Technology Areas: Biomaterials & Bioelectronics / Therapeutics
Impact Areas: Healthy Living
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Rapid Droplet-Based Systems for Antibody Drug Discovery

Technology / Case number: #23890J
Brandon DeKosky / Matias Gutierrez Gonzalez / Cheng-yu Chung / Ahmed Fahad / Nicoleen Boyle / Shuyan Jin
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
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High-throughput Electroporation Device

Technology / Case number: #21871
Cullen Buie / Po-Hsun Huang / Sijie Chen
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Industrial Engineering & Automation
Impact Areas: Healthy Living
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Dysferlinopathy Compounds

Technology, Tangible Property / Case number: #22496
Mohan Viswanathan / Eric Williams / Kana Tominaga / Naoomi Tominaga / Leonard Guarente
Technology Areas: Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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Single Cell Super-Resolution Proteomics

Technology / Case number: #24088
Mark Harnett / Dimitra Vardalaki
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living, Uncharted Frontiers
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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