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Water Desalination

Top view of a large desalination facility

Harnessing science to turn seawater into sustainable freshwater, solving global water scarcity.

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Genomic Insertion of Large Cargo with Engineered Retro Elements

Technology / Case number: #23248
Omar Abudayyeh / Jonathan S. Gootenberg / Lukas Villiger / Justin Lim
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Ligand-Inducible Post-Transcriptional Gene Regulation Using Protein-Binding RNA Aptamers

Technology / Case number: #13998J
Brian Belmont / Stephen Goldfless / Jacquin Niles / Michael Marletta
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Dendrimer and Peptide Based Excipients for the Attenuation of Protein Aggregation

Technology / Case number: #14184
Curtiss Schneider / Diwakar Shukla / Bernhardt Trout
Technology Areas: Chemicals & Materials / Industrial Engineering & Automation / Therapeutics
Impact Areas: Healthy Living
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The Design of DNA-scaffolded Subunit Vaccines for Enhanced Germinal Center Responses in HIV Vaccination

Technology / Case number: #25982H
Mark Bathe / Grant Knappe / Anna Romanov / Darrell J Irvine
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Advanced Materials
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Tissue Specific Delivery of Interfering RNA

Technology / Case number: #13947H
Yin Ren / Sangeeta Bhatia
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Structured Spheres Generated by an In-Fibre Fluid Instability

Technology / Case number: #15704J
Ayman Abouraddy / Daosheng Deng / Xiangdong Liang / Soroush Shabahang / Guangming Tao / Esmaeil Banaei / Joshua Kaufman / Yoel Fink / Steven G Johnson
Technology Areas: Chemicals & Materials / Industrial Engineering & Automation
Impact Areas: Advanced Materials
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Peptide Nucleic Acid Functionalized Hydrogel Microneedles for Sampling and Detection of Interstitial Fluid Nucleic Acids

Technology / Case number: #21359HJ
Yin Hao Chang / Sylvain Ladame / Dana Al Sulaiman / Darrell J Irvine
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Fusion Vacuum Vessel Replacement with Mechanical Radial Insertion of Toroidal Sectors and Thermally Activated Sector-to-Sector Vacuum Seals

Technology / Case number: #25882
Michael Short / Dennis Whyte / Jonas Rajagopal / Nikola Goles / Ben Clark / Stanley Normile / Stefano Segantin
Technology Areas: Industrial Engineering & Automation
Impact Areas: Advanced Materials
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Development of a Platform to Noninvasively Image Car T Cells

Technology / Case number: #25905J
Michael Hemann / Mohammad Rashidian / Jennifer Rowley / Taha Rakhshandehroo / Ali Salehi / Julia Froese
Technology Areas: Biotechnology / Sensing & Imaging / Therapeutics
Impact Areas: Healthy Living
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A Magnetically Attached Hull Cleaning Robot with Hydrodynamic Downforce

Technology / Case number: #25694
Levi Gershon / Henry Sobieszczyk / Pierre Lonni / Keeghan Patrick / Diane Li / Juliana Green
Technology Areas: Industrial Engineering & Automation
Impact Areas: Advanced Materials
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Pulsing Light to Promote Recovery from Amblyopia

Technology / Case number: #25767P
Mark Bear / Francis Reilly-Andujar
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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One-Step Construction of Allogeneic CAR-NK Cells with Increased Anti-Tumor Cytotoxicity and Resistant to Rejection by Host T Cells and NK Cells

Technology / Case number: #25757J
Rizwan Romee / Fuguo Liu / Jianzhu Chen
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Vaccine Targeting to Mucosal Lymphoid Tissues in the Gastrointestinal Tract

Technology / Case number: #25463H
Ozgun Kocabiyik / Darrell J Irvine
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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High Torque-Density Mechanical Couplings with Variable Slip Control

Technology / Case number: #25196
Charles Wheeler
Technology Areas: Industrial Engineering & Automation
Impact Areas: Advanced Materials
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Micro-Invasive Neural System for Delivering Antiseizure Medications to the Epileptic Focus for the Treatment of Refractory Epilepsy

Technology / Case number: #25721J
Michael Cima / Max Cotler / Hannah Jackson / Cameron Metcalf / Karen Wilcox / Peter West
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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FISHTALE- Fluorescent In Situ Hybridization of TAL Effectors

Technology / Case number: #19813TE
Edward Stuart Boyden / Adam Marblestone / Samuel Rodriques / Nicholas Barry
Technology Areas: Sensing & Imaging / Therapeutics
Impact Areas: Healthy Living
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RNA Degradation-based Toggle Switch

Technology / Case number: #21622
Ron Weiss / Breanna DiAndreth / Noreen Wauford
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Persistent-Mode MRI Magnet Fabricated from Reacted, Monofilamentary MgB2 Wires

Technology / Case number: #16305
Yukikazu Iwasa / Seung-Yong Hahn / Juan Bascunan / John Voccio / YoungJae Kim / Jungbin Song / Jiayin Ling
Technology Areas: Biotechnology / Industrial Engineering & Automation / Sensing & Imaging
Impact Areas: Healthy Living
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Enhanced Evaporative Heat Transfer Device Using Porous Membranes

Technology / Case number: #16063K
Evelyn N. Wang / Ryan Enright / Shalabh Maroo / Rong Xiao / Shankar Narayan / Rishi Raj
Technology Areas: Energy & Distribution / Industrial Engineering & Automation
Impact Areas: Connected World
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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