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Methods, Procedures, and Material Compositions to Formulate Thermally Stable Solid-State Lipid Nanoparticles via Drying at Ambient Conditions

Technology / Case number: #26177
Robert Langer / Amy Lee / Khanh Tran / Jinbi Tian / Mina Konakovic Lukovic / Ana Jaklenec
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Poly(-amino ester) Microparticles for Micronutrient Fortification

Technology / Case number: #22992
Robert Langer / Linzixuan Rhoda Zhang / Ruiqing Xiao / Ana Jaklenec
Technology Areas: Agriculture & Food / Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living
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AO mRNA-LNP Stabilization

Technology / Case number: #26266
Robert Langer / Tina Huang / Jooli Han / Linzixuan Rhoda Zhang / Ana Jaklenec
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Lipid-Polymer Microparticles (mLPM) For Thermostable, Pulsatile mRNA-LNP Vaccines

Technology / Case number: #26154
Robert Langer / Yuting Huang / Linzixuan Rhoda Zhang / Ana Jaklenec
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Branched Poly(-amino esters) for the Delivery of Nucleic Acids

Technology / Case number: #20333JQ
Robert Langer / Gary Liu / James Byrne / Netra Kamat / Hyunjoon Kim / Daniel Reker / Grace Junyue Zhong / Ameya Kirtane / Yunhua Shi / Giovanni Traverso
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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A Mechanical Underwater Soft Adhesion System for Kinetic Biosensing and Intelligent Targeted Drug Delivery

Technology / Case number: #26028J
Giovanni Traverso / Yubin Cai / Troy Ziliang Kang / Ming Zhao / Ameya Kirtane
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Hydrogen from Air: Decentralized Sorption-based Atmospheric Water Hydrogen Device

Technology / Case number: #26048
Chad Wilson / David Keisar / Joseph Phelim Mooney / Carlos Diaz Marin / Bachir El Fil
Technology Areas: Environmental Engineering
Impact Areas: Sustainable Future
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Lipid Compositions and Methods

Technology / Case number: #25115J
Daniel Anderson / Dennis Shi / Theresa Raimondo / Sho Toyonaga
Technology Areas: Drug Delivery
Impact Areas: Healthy Living
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Large-Scale Long-Term (Months) High-Temperature (1800°C) Heat Storage

Technology / Case number: #26135
Charles Forsberg
Technology Areas: Energy & Distribution / Environmental Engineering
Impact Areas: Sustainable Future
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Synergisms between Small Molecule Boosters and LNP Formulations Uncovered using High Throughput Screening and Machine Learning

Technology / Case number: #26199J
Giovanni Traverso / Deepak Subramanian / Rajib Dey / Ameya Kirtane
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Biodegradable Lipid-Like Materials for Applications in siRNA Delivery

Technology / Case number: #15420
Robert Langer / Joseph Dorkin / Yunlong Zhang / Arturo Vegas / Kathryn Whitehead / Daniel Anderson
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Compositions and Methods to Deliver RNA to Extracellular Matrix Producing Cells

Technology / Case number: #25390J
Daniel Anderson / Dennis Shi / Theresa Raimondo / Sho Toyonaga
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Echo Tops 0-2 Hour Forecast

Technology, Software / Case number: #11759L
Marilyn Wolfson / Bill Dupree
Technology Areas: Communication Systems / Environmental Engineering
Impact Areas: Sustainable Future, Connected World
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Self- Regulated Peptide Hydrogel for Closed Loop Insulin Delivery

Technology / Case number: #15056J
Robert Langer / Alex Aimetti / Zhen Gu / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living
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Porous Polysulfone Particles for Oil Absorption

Technology / Case number: #15287
Kripa K Varanasi / Brian Solomon / Nasim Hyder
Technology Areas: Chemicals & Materials / Environmental Engineering
Impact Areas: Sustainable Future
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Biodegradable Polyamine-Fatty Acid Derived Lipidoids for Drug Delivery

Technology / Case number: #16367
Daniel Anderson / Rebecca McClellan / Owen Fenton / Joseph Dorkin
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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1,2-Aminoalcohol Lipidoids (II)

Technology / Case number: #13661Q
Robert Langer / Kathryn Whitehead / Kevin Love / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living
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Formulation of Polymeric Particles for Prostate Cancer Targeting

Technology / Case number: #12162J
Robert Langer / Omid Farokhzad
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Immune Pharmacytes: Nanoparticle-Modified Leukocytes for Immunotherapy

Technology / Case number: #13509H
Darrell J Irvine
Technology Areas: Diagnostics / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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MEMS Piezoelectric Energy Harvester With Residual Stress Induced Instability

Technology / Case number: #17145
Sang-Gook Kim / Ruize Xu
Technology Areas: Chemicals & Materials / Energy & Distribution / Environmental Engineering
Impact Areas: Sustainable Future, Connected World
License

The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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