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User-Friendly and Easily-Accessible Synthetic Hydrogels for Biomaterials Application

Technology / Case number: #20694
Owen Fenton / Robert Langer / Jason Andresen / Marion Paolini
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Pore Creation Methods in Monolayer Graphene for Membrane Applications

Technology / Case number: #18915J
Jing Kong / Rohit Karnik / Tahar Laoui / Piran Kidambi / Ahmed Ibrahim / Sui Zhang
Technology Areas: Chemicals & Materials / Energy & Distribution / Environmental Engineering
Impact Areas: Advanced Materials
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Distributed Mechanisms and Actuation in Digital Materials

Technology / Case number: #19890X
William Langford / Amanda Ghassaei / Neil Gershenfeld
Technology Areas: Chemicals & Materials / Energy & Distribution / Industrial Engineering & Automation
Impact Areas: Advanced Materials
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Ionizable Lipids for Messenger RNA Delivery

Technology, Tangible Property / Case number: #24861
Jacob Witten / Idris Raji / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Delivery / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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A Generalizable, High-Throughput Method to Rapidly add Chemical Moieties to a Small Molecule Library

Technology / Case number: #22196J
Angela Koehler / Brice Curtin / Jasmin Kruell / Catherine Henry / Sebastian Pomplun / Christina Woo / Chia-fu Chang
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Small Molecule Inhibitors of Interleukin-4

Technology / Case number: #22186J
Angela Koehler / Arturo Vegas / Shelby Doyle / Becky Leifer / Sean Quinnell / Stephen Nestor / Kelly Tan / Luke Ceo / Daniel Sheehy
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Chimeric Degraders of Cyclin Dependent Kinase 9 with Potential Use for Cancer Therapy

Technology / Case number: #22028
Angela Koehler / Andre Richters / Julie Urgiles / Florian Kabinger / Mohammed Toure
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Small Molecule Modulators of the Androgen Receptor

Technology / Case number: #19771
Angela Koehler / Nicholas Struntz / David Freeman / Shelby Doyle / Andre Richters
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Novel Max Binders Modulators of Myc-Mediated Transcription with Potential Use for Cancer Therapy

Technology / Case number: #18257
Angela Koehler / Eric Stefan / Francisco Caballero Gonzalez / Dylan Neel / Helen Evans / Nicholas Struntz / Andrew Chen
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Upconversion Utilizing Thin Film Colloidal Nanocrystals and Organic Materials

Technology / Case number: #17808
Daniel Congreve / Nicholas Thompson / Mark Wilson / Mengfei Wu / Moungi Bawendi / Vladimir Bulovic / Marc Baldo
Technology Areas: Biotechnology / Chemicals & Materials / Energy & Distribution
Impact Areas: Advanced Materials
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Hybrid Materials with Living Cells and Tough Hydrogels

Technology / Case number: #18548
Timothy Lu / Xuanhe Zhao / Eleonore Tham / Xinyue Liu / Tzu-Chieh Tang
Technology Areas: Biomaterials & Bioelectronics / Chemicals & Materials / Diagnostics / Therapeutics
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Pooled Screening Identifies Genomic Features (Biomarkers) Modulating Nanoparticle-Cell Interactions

Technology / Case number: #22785J
Angela Koehler / Natalie Boehnke / Joelle Straehla / Paula Hammond
Technology Areas: Diagnostics / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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Cationic Lipidoids and Their Uses for Immunotherapy

Technology / Case number: #19803
Linxian Li / Yuxuan Huang / Lei Miao / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Synthesis of Ester, Carbonate, and Carbamate-derived Novel Biodegradable Ionizable Lipids from Methyl Ricinoleate or Methyl 12-Hydroxystearate and its Applications

Technology / Case number: #23381Q
Luke Rhym / Bowen Li / Akiva Gordon / Manan manan / Jacob Witten / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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A New Class of High Energy Li Primary Battery Cathodes Utilizing the Defluorination of Pentafluorosulfanyl Group

Technology / Case number: #24100
Betar Gallant / Haining Gao
Technology Areas: Energy & Distribution
Impact Areas: Advanced Materials
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Far Infra-Red Detection Using Certain Semi-Metals

Technology / Case number: #18916J
Qiong Ma / Nuh Gedik / Ching-Kit Chan / Gil Refael / Netanel Lindner / Suyang Xu / Patrick Lee
Technology Areas: Chemicals & Materials / Electronics & Photonics / Energy & Distribution
Impact Areas: Advanced Materials
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Enhanced Vaccine Immunogenicity Enabled by Targeted Delivery of Tumor Antigens into Dendritic Cells

Technology / Case number: #25054H
Bradley Pentelute / Cameron Hanna / Emi Lutz / Simon Roessler / Nicholas Truex / Aurelie Rondon / Yehlin Cho / Coralie M. Backlund / Binyou Wang / Darrell Irvine
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Lipid Anchorage of Cytokines onto Layer-by-Layer Nanoparticles

Technology / Case number: #25070H
Ivan Susin Pires / Darrell Irvine / Paula Hammond
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Combinations of Anesthetics as Therapies for Treatment-Resistant Depression

Technology / Case number: #25342P
Emery Brown / Sirma Orguc / Ohyoon Kwon / Bryan Tseng / Macauley Breault / Gloria Kang
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Engineered Synthetic IRES with Improved and Robust Translation in Circular RNA

Technology / Case number: #25300YJ
James Collins / Katherine Ilia / Shiva Razavi / Kehan Zhang / Xiaoyu Chen / Makoto Lalwani / Yu Li / Nayoung Kim
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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