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Invention Disclosure: Kinetic Sensing, Signal Generation, Feature Extraction, and Pattern Recognition for Control of Autonomous Wearable Leg Devices

Technology / Case number: #18945TE
Luke Mooney / Matthew Carney / Roman Stolyarov / Cameron Taylor / Hugh Herr
Technology Areas: Biotechnology / Industrial Engineering & Automation
Impact Areas: Healthy Living
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Single-Step Insertion into Repeated Regions for Efficient Multi-Locus Assortment and Daisyfield Drive

Technology / Case number: #19136TJE
Kevin Esvelt / Jianghong Min / Charleston Noble
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living, Uncharted Frontiers
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Aryl Sulfonamides Derived From Nucleophilic Aromatic Substitution Reactions

Technology / Case number: #19263J
Jeremiah Johnson / Mao Chen / Wenxu Zhang / Mingjun Huang / Shuting Feng / Livia Giordano / Robinson Anandakathir / Yang Shao-Horn
Technology Areas: Energy & Distribution
Impact Areas: Advanced Materials
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Transdermal Optogenetic Peripheral Nerve Stimulation

Technology / Case number: #18928TE
Anthony Zorzos / Benjamin Maimon / Hugh Herr
Technology Areas: Biotechnology
Impact Areas: Healthy Living, Uncharted Frontiers
License

Human-Activity Kinetic Alignment (HAKA)

Technology / Case number: #19889L
Richard Shay / Robert Cunningham
Technology Areas: Biotechnology / Communication Systems / Computer Science
Impact Areas: Healthy Living
License

Molecular Spatial Mapping Of Metastatic Tumor Microenvironment

Technology / Case number: #22132HR
Aviv Regev / Johanna Klughammer / Daniel Abravanel / No Inventor
Technology Areas: Biotechnology / Computer Science
Impact Areas: Healthy Living
License

Method and Apparatus to Accelerate the Process of Falling Asleep

Technology / Case number: #19927TEJ
Edward Boyden / Nir Grossman / David Wang
Technology Areas: Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
License

Neural Efferent and Afferent Control of Spring Equilibrium, Damping, and Power in Backdrivable and Non-Backdrivable Series-Elastic Actuators Comprising Variable Series Stiffness Mechanisms

Technology / Case number: #20960TE
Matthew Carney / Roman Stolyarov / Emily Rogers-Bradley / Seong Ho Yeon / Hugh Herr
Technology Areas: Biotechnology / Computer Science / Industrial Engineering & Automation
Impact Areas: Healthy Living
License

Optimized Opsin Trafficking with Fluorescence-Dead Protein Fusions

Technology / Case number: #18783TE
Edward Boyden / Kiryl Piatkevich / Aimei Yang / Demian Park
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
License

Modular System for Lyophilization

Technology / Case number: #22603
Alexander Slocum / Bernhardt Trout
Technology Areas: Biotechnology / Chemicals & Materials / Industrial Engineering & Automation
Impact Areas: Healthy Living
License

Methods for Identifying and Modulating Co-occurant Cellular Phenotypes

Technology / Case number: #19998R
Alexander Shalek / Alex Genshaft / Carly Ziegler / Jeffrey Van Humbeck / Ryan King / No Inventor
Technology Areas: Biotechnology / Computer Science
Impact Areas: Healthy Living
License

A Stretchable, Wearable Ultrasound Transducer for Wide-Scale Breast Cancer Data Collection

Technology / Case number: #20934TE
Canan Dagdeviren / Lin Zhang
Technology Areas: Biotechnology / Diagnostics
Impact Areas: Healthy Living
License

Improving Statistical Model-Based Speech Enhancement with Deep Neural Networks

Technology / Case number: #21028L
Bengt Borgstrom / Michael Brandstein / Robert Dunn
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Communication Systems / Computer Science / Sensing & Imaging
Impact Areas: Healthy Living, Connected World, Advanced Materials
License

Methods for the Treatment of Trinucleotide Repeat Expansion Disorders Associated with FAN1 activity via Targeting of FAN1 Splice Site Inhibitory Sequences

Technology / Case number: #24829
Christopher Ng / David Housman
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
License

Method for Zero Phase-Lag Real-Time Computation of Hilbert Transform and Analytic Signal

Technology / Case number: #18073TEJ
Edward Boyden / Nir Grossman / David Wang
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
License

Neuromechanical Interventions for the Mitigation of Limb Pathology

Technology / Case number: #18430TE
Anthony Zorzos / Benjamin Maimon / Matthew Carty / Tyler Clites / Jean-Francois Duval / Shriya Srinivasan / Hugh Herr
Technology Areas: Biotechnology
Impact Areas: Healthy Living
License

Oral Pill Water-Tight Payload Chamber Design with Triggerable Release

Technology / Case number: #25209J
Carlo Giovanni Traverso / Miguel Jimenez / James McRae / Emily Kolaya
Technology Areas: Biotechnology
Impact Areas: Healthy Living
License

Methods and Apparatuses to Track Hand Configurations based on Ultrasound Signals

Technology / Case number: #25586
Xuanhe Zhao / Gengxi Lu
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Computer Science
Impact Areas: Healthy Living, Connected World
License

Closed-Loop Noninvasive Brain Stimulation with Simultaneous Imaging to Control Cerebrospinal Fluid Flow in Humans

Technology / Case number: #25482
Laura Lewis / Joshua Levitt
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Computer Science / Sensing & Imaging
Impact Areas: Healthy Living
License

A Microphysiological Model of the Brain Including Blood-brain Barrier, Neural Tissue and Meningeal Lymphatics

Technology / Case number: #24291
Roger Kamm / Giovanni Offeddu / Shun Zhang / Marie Floryan / Georgios Pavlou / Cynthia Hajal / Sarah Spitz / Jean Serrano Flores / Eunkyung Ko / Yoojin Shin / Xun Wang
Technology Areas: Biotechnology
Impact Areas: Healthy Living
License

The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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