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Lipid-Polymer Microparticles (mLPM) For Thermostable, Pulsatile mRNA-LNP Vaccines

Technology / Case number: #26154
Robert Langer / Yuting Huang / Linzixuan Rhoda Zhang / Ana Jaklenec
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Polymeric Core-Shell Particles for Pulsatile Release of HIV Vaccine

Technology / Case number: #26230
Robert Langer / Stacey Lin / Aki Gurram / Rishi Das / Amy Lee / Behnaz Eshaghi / Maria Kanelli / Ana Jaklenec
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Transistor Structure and Method of Forming the Same

Technology / Case number: #25279
Tomas Palacios / Gillian Micale / Pao-Chuan Shih / John Niroula / Qingyun Xie
Technology Areas: Chemicals & Materials / Electronics & Photonics / Energy & Distribution
Impact Areas: Connected World
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Branched Poly(-amino esters) for the Delivery of Nucleic Acids

Technology / Case number: #20333JQ
Robert Langer / Gary Liu / James Byrne / Netra Kamat / Hyunjoon Kim / Daniel Reker / Grace Junyue Zhong / Ameya Kirtane / Yunhua Shi / Giovanni Traverso
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Amino Acid, Peptide, Polypeptide-Lipids (APPL) Derivatives and Uses Thereof

Technology / Case number: #14910Q
Robert Langer / Akinleye Alabi / Yunlong Zhang / Yizhou Dong / Yi Chen / Delai Chen / Arturo Vegas / Kevin Love / Daniel Anderson
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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An Ultra-Wide-Band-Gap Semiconductor Optical Switch that is Capable of Fast Turn-Off and Achieves High Current Density with Visible Light at Low Irradiance

Technology / Case number: #26249
Rafael Jaramillo / Jiahao Dong
Technology Areas: Electronics & Photonics / Sensing & Imaging
Impact Areas: Advanced Materials
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A MEMS Based Encapsulated Hydrophone

Technology / Case number: #26013LJ
Daniel Freeman / James Vlahakis / Georgios Karamanis / Jonathan Anderson / Robert White
Technology Areas: Chemicals & Materials / Electronics & Photonics / Industrial Engineering & Automation / Sensing & Imaging
Impact Areas: Sustainable Future, Connected World
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Velocimetric Sensing and High-Speed Transport Method and Apparatus for Magnetically-Tagged Biological and Chemical Entities Using Magnetic Domain Walls in Lithographically Defined Thin-Film Magnetic

Technology / Case number: #14609
Geoffrey Stephen Beach / Elizabeth Rapoport
Technology Areas: Chemicals & Materials / Electronics & Photonics
Impact Areas: Advanced Materials
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Fuse Protected Avalanche Photodiode Arrays

Technology / Case number: #16733L
Michael Grzesik
Technology Areas: Chemicals & Materials / Electronics & Photonics
Impact Areas: Advanced Materials
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Printed Circuit Board with Rohacell Hybrid Via Process

Technology / Case number: #17133L
Glenn Brigham
Technology Areas: Chemicals & Materials / Electronics & Photonics
Impact Areas: Advanced Materials
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Cross-Talk Suppression Filters for Geiger-Mode Avalanche Photodiodes

Technology / Case number: #13695L
Joseph Donnelly / Rich Younger / Erik Duerr / Tony Napoleone / David Chapman / Douglas Oakley / Simon Verghese / Alex McIntosh
Technology Areas: Computer Science / Electronics & Photonics
Impact Areas: Connected World
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Method to Improve the Image Quality of Positron Emission Tomography When Using Non-Standard Isotopes Based on Triple Coincidences

Technology / Case number: #16135
Shivang Dave / Joaquin Herraiz / Eduardo Lage / Vicente Parot
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Communication Systems / Electronics & Photonics / Sensing & Imaging
Impact Areas: Healthy Living
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Optical Filters with Engineered Birefringence

Technology / Case number: #16393L
Mordechai Rothschild / Kenneth Diest / Vladimir Liberman
Technology Areas: Chemicals & Materials / Communication Systems / Electronics & Photonics
Impact Areas: Connected World
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Liquid Crystal Alignment Layer

Technology / Case number: #17358LJ
Carl Bozler / Douglas Bryant / Philip Bos / Valerie Finnemeyer / Shaun Berry / Robert Reich / Harry Clark
Technology Areas: Chemicals & Materials / Electronics & Photonics
Impact Areas: Connected World
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Absorbing Films Deposited and Patterned with Soft Lithography

Technology / Case number: #12080
Vladimir Bulovic / Michael Bradley / Jonathan Tischler
Technology Areas: Chemicals & Materials / Electronics & Photonics / Industrial Engineering & Automation
Impact Areas: Advanced Materials
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Method for Quantitative Monitoring of In Vivo Tumor Oxygenation

Technology / Case number: #19207JQ
Michael Cima / Ehud Schmidt / Robert Cormack / Larissa Lee / Gregory Ekchian
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Reprogram the Genome of M13 Phage for Vaccination and Immunotherapy Applications

Technology / Case number: #25169
Angela Belcher / Shengnan Huang
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Exceptional-Point Magnetometry with a Self-Oscillating Hybrid Quantum System

Technology / Case number: #26014J
Dirk R Englund / Hanfeng Wang / Donald Fahey / Kurt Jacobs / Matthew Trusheim
Technology Areas: Chemicals & Materials / Electronics & Photonics
Impact Areas: Advanced Materials
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A Mechanical Underwater Soft Adhesion System for Kinetic Biosensing and Intelligent Targeted Drug Delivery

Technology / Case number: #26028J
Giovanni Traverso / Yubin Cai / Troy Ziliang Kang / Ming Zhao / Ameya Kirtane
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Expression Constructs for One-Step Construction of Allogeneic CAR-NK Cells

Technology, Tangible Property / Case number: #26118J
Jianzhu Chen / Fuguo Liu / Rizwan Romee
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Connected World
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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