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Fanzors are RNA-Guided Nucleases Encoded in Eukaryotic Genomes

Technology / Case number: #24942
Omar Abudayyeh / Kaiyi Jiang / Justin Lim / Jonathan S. Gootenberg
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Machine Learned Chemical Intuition for the AI Generation of Molecules within Specific Chemical Spaces

Technology / Case number: #26403
Brett McGuire / Zachary Fried
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Sub-13.5 nm Projection Lithography System and Components

Technology / Case number: #26289L
Mordechai Rothschild / Paul Chesler / Nate O'Connor / Peter Moulton / Tommy Sebastian / Vladimir Liberman
Technology Areas: Chemicals & Materials / Electronics & Photonics / Industrial Engineering & Automation
Impact Areas: Connected World, Advanced Materials
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Oxygen-Generating Scaffolds for Stem Cell Depot Support

Technology / Case number: #24650J
Giovanni Traverso / Young-Geun Park
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Methods, Procedures, and Material Compositions to Formulate Thermally Stable Solid-State Lipid Nanoparticles via Drying at Ambient Conditions

Technology / Case number: #26177
Robert Langer / Amy Lee / Khanh Tran / Jinbi Tian / Mina Konakovic Lukovic / Ana Jaklenec
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Compacted Powder Needles for Intramucosal Delivery

Technology / Case number: #21149QJ
Giovanni Traverso / Morten Frederiksen
Technology Areas: Biomaterials & Bioelectronics / Therapeutics
Impact Areas: Healthy Living
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Automated Flow Synthesis of Combinatorial Protein Libraries

Technology / Case number: #26382J
Bradley L. Pentelute / Dimuthu Vithanage / Corey Johnson / John Albin / Gha Young Lee / Wayne Vuong
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Optical Neural Network Accelerator for Deep Learning

Technology / Case number: #26433J
Dirk R Englund / Chao Luan / Ryan Hamerly
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science / Electronics & Photonics
Impact Areas: Connected World
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Pulsed Seed Laser Selection to Minimize Spectral Broadening in Pulsed Fiber Laser

Technology / Case number: #25457L
John Kim / Luis Ortega / Mike Riley / Kelsey Johnsen
Technology Areas: Communication Systems / Electronics & Photonics / Sensing & Imaging
Impact Areas: Advanced Materials
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High Efficiency 3-Coil Coreless Power Transformer

Technology / Case number: #25633
Chathan M Cooke / Noah Salk
Technology Areas: Electronics & Photonics / Energy & Distribution / Industrial Engineering & Automation
Impact Areas: Sustainable Future
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Channel Scalable, Coherent Beam Combined Laser Architecture

Technology / Case number: #25507L
Tso Yee Fan / Kan Thach / Luis Ortega / Louis Isabella / Kelsey Johnsen / Yin Wan Tam / John Kim / Niyom Lue
Technology Areas: Electronics & Photonics / Sensing & Imaging
Impact Areas: Connected World, Advanced Materials
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Embedded Hard-Stop Interconnect Spacers for 3D/Flip-Chip Integrated Superconducting Qubit Module

Technology / Case number: #26145L
William Oliver / Bethany Huffman / David Kim / Mollie Schwartz / Jonilyn Yoder / Rabindra Das
Technology Areas: Chemicals & Materials / Electronics & Photonics / Industrial Engineering & Automation
Impact Areas: Connected World
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Cavity-Enhanced Solid-State Nuclear Spin Gyroscope

Technology / Case number: #26298
Dirk R Englund / Hanfeng Wang / Matthew Trusheim
Technology Areas: Electronics & Photonics / Energy & Distribution / Sensing & Imaging
Impact Areas: Connected World
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Innate Immune Modulating RNA Vaccines

Technology / Case number: #26293H
Darrell J Irvine / B.j. Kim
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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AO mRNA-LNP Stabilization

Technology / Case number: #26266
Robert Langer / Tina Huang / Jooli Han / Linzixuan Rhoda Zhang / Ana Jaklenec
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Apparatus, Systems, and Methods for Heterogeneous Integration and Combinatorial Material Processing

Technology / Case number: #26290
Caroline Ross / Jorge Marquez Chavez / Brian Mills / Khoi Dao / Juejun Hu
Technology Areas: Electronics & Photonics / Energy & Distribution
Impact Areas: Advanced Materials
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Prolonged-Release Hydrogel Formulations of Toll-Like Receptor Agonists for Intratumoral Injection to Increase Immunotherapy Response

Technology / Case number: #23215J
Robert Langer / Umar Mahmood / Eric Wehrenberg-Klee / Gabrielle Ndakwah / Jan-Georg Rosenboom / Avik Som / Arijit Basu / Giovanni Traverso
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Systems, Devices, and Methods Utilizing Hybrid Photonic Crystal Cavities

Technology / Case number: #26325J
Dirk R Englund / Andy Greenspon / Mark Dong
Technology Areas: Computer Science / Electronics & Photonics / Energy & Distribution
Impact Areas: Connected World
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Plk1 inhibitor and Microtubule Poison Dual Payload Antibody Drug Conjugates for the Treatment of Cancer

Technology / Case number: #26136
Michael Yaffe / Jesse C Patterson
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Multi-Waveguide Beam Scanners and Scanning Pattern Methods

Technology / Case number: #26324J
Dirk R Englund / Matthew Zimmermann / Henry Wen
Technology Areas: Biotechnology / Electronics & Photonics / Energy & Distribution / Industrial Engineering & Automation
Impact Areas: Sustainable Future, Connected World
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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