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Hardware Models of Biochemical Reaction Networks

Technology / Case number: #13076
Rahul Sarpeshkar
Technology Areas: Biotechnology / Computer Science
Impact Areas: Healthy Living
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Colloidal Hydrogel Particles with tunable Chemistry, Geometry, and Flexibility

Technology / Case number: #13461J
Patrick Doyle / Daniel Pregibon / Ramin Haghgooie / Mehmet Toner
Technology Areas: Chemicals & Materials / Computer Science
Impact Areas: Healthy Living
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Biodegradable Lipid-Like Materials for Applications in siRNA Delivery

Technology / Case number: #15420
Kathryn Whitehead / Arturo Vegas / Yunlong Zhang / Joseph Dorkin / Robert Langer / Daniel Anderson
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Self- Regulated Peptide Hydrogel for Closed Loop Insulin Delivery

Technology / Case number: #15056J
Zhen Gu / Alex Aimetti / Robert Langer / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living
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Methods for Microbial Oil Overproduction via Amplification of the Biosynthetic and Sequestration Pathways Individually or in Combination

Technology / Case number: #15152
Mitchell Tai / Sagar Chakraborty / Gregory Stephanopoulos
Technology Areas: Biotechnology / Chemicals & Materials / Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Translocation of Non-Natural Chemical Entities Through Anthrax Protective Antigen Pore

Technology / Case number: #15639J
Bradley L. Pentelute / Xiaoli Liao / Amy Rabideau / Jingjing Ling / Gizem Akcay / R. Collier
Technology Areas: Computer Science / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Novel Glucose-Responsive Insulin Formulations Using Chemically Modified Insulin Derivatives and Non-Covalent Insulin-Binding Molecules

Technology / Case number: #15976J
Arturo Vegas / Yair Levi / Yunlong Zhang / Benjamin Tang / Hung-Chieh (Danny) Chou / Kun Xue / Matthew Webber / Rosemary Kanasty / Robert Langer / Daniel Anderson
Technology Areas: Chemicals & Materials / Computer Science / Therapeutics
Impact Areas: Healthy Living
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Distinct Gene Systems Mediating Activity-Dependent Plasticity in Visual Cortex

Technology / Case number: #11841P
Shayan Mukherjee / Daniela Tropea / Gabriel Kreiman / Mriganka Sur / Alvin Lyckman
Technology Areas: Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Glucose Valve and Other Metabolite Valves

Technology / Case number: #12369
Tae Moon / Kristala L Jones Prather / Kevin Solomon
Technology Areas: Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Reverse Micelle Nanoprecipitation: A Method for Encapsulating Nucleic Acids in Biodegradable Polymers

Technology / Case number: #12561J
Aleksandar Radovic-Moreno / Liangfang Zhang / Robert Langer / Omid Farokhzad
Technology Areas: Chemicals & Materials / Computer Science / Electronics & Photonics
Impact Areas: Healthy Living, Advanced Materials
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Olfactory Receptor-Based Devices

Technology / Case number: #12776TE
Manu Prakash / Andreas Mershin / Brian Cook / Joanke (Johanna) Bikker Graveland / Liselotte Kaiser / Shuguang Zhang / Yael Maguire / David Kong
Technology Areas: Biotechnology / Chemicals & Materials / Computer Science / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Transcriptional Engineering of Lactobacillus for Improved Lactic Acid Tolerance and Productivity at Low pH

Technology / Case number: #12783
Daniel Klein-Marcuschamer / Gregory Stephanopoulos
Technology Areas: Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
License

Extension of a Finite Element Framework for Calculation of DNA Nanostructure Solution Shape, Mechanical, and Optical Properties

Technology / Case number: #16421
Mark Bathe / Do-Nyun Kim / Matthew Adendorff / Keyao Pan / Lun Yang / Reza Sharifi Sedeh / Etienne Boulais / Oskar Hallatschek / Klaus-Jurgen Bathe
Technology Areas: Computer Science
Impact Areas: Healthy Living
License

Biodegradable Polyamine-Fatty Acid Derived Lipidoids for Drug Delivery

Technology / Case number: #16367
Joseph Dorkin / Owen Fenton / Rebecca McClellan / Daniel Anderson
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
License

1,2-Aminoalcohol Lipidoids (II)

Technology / Case number: #13661Q
Kerry Mahon / Kevin Love / Christopher Levins / Kathryn Whitehead / Robert Langer / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living
License

Normalization Correction for Inter-Detector Scatter Enhanced Positron Emission Tomography

Technology / Case number: #16136
Shivang Dave / Vicente Parot / Eduardo Lage / Joaquin Herraiz
Technology Areas: Computer Science / Sensing & Imaging
Impact Areas: Healthy Living
License

Formulation of Polymeric Particles for Prostate Cancer Targeting

Technology / Case number: #12162J
Jianjun Cheng / Benjamin Teply / Stephen Zale / Robert Langer / Omid Farokhzad
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
License

Immune Pharmacytes: Nanoparticle-Modified Leukocytes for Immunotherapy

Technology / Case number: #13509H
Matthias Stephan / Jae Hyun (James) Moon / Anna Bershteyn / Darrell J Irvine
Technology Areas: Diagnostics / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
License

Microbial Production of 3,4-Dihydroxybutyrate (DHBA) and 3-Hydroxybutyrolactone (3-HBL) from Glucose

Technology / Case number: #14595
Kristala L Jones Prather / Collin Martin / Himanshu Dhamankar
Technology Areas: Chemicals & Materials / Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
License

Protein Retrosplicing Enabled by a Double Ligation Reaction

Technology / Case number: #15368
Bradley L. Pentelute / Xiaoli Liao / Amy Rabideau / Jingjing Ling / Rocco Policarpo
Technology Areas: Computer Science / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
License

The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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