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Self Actuating Systems for Retention and Electrical Stimulation in the Gastrointestinal Tract

Technology / Case number: #20292JQ
Robert Langer / David Dellal / Ester Caffarel Salvador / Niclas Roxhed / Minsoo Khang / Alex Abramson / Taylor Bensel / Giovanni Traverso
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Solid Formulations with Ultra-High Drug Loading

Technology / Case number: #19446J
Robert Langer / Ester Caffarel Salvador / Niclas Roxhed / Minsoo Khang / Alex Abramson / Taylor Bensel / Giovanni Traverso
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Multi-Pronged Self-Orienting Millimeter-Scale Actuator for Drug Delivery

Technology / Case number: #21169JQ
Robert Langer / Jacob Wainer / Michael Williams / Alex Abramson / Giovanni Traverso
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Rare Earth Spatial/Spectral Barcodes for Multiplexed Biochemical Testing

Technology / Case number: #15231L
Patrick Doyle / Ji Seok Lee / Paul Bisso / Albert Swiston
Technology Areas: Biotechnology / Diagnostics
Impact Areas: Healthy Living, Advanced Materials
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Injectable, Thermogelling, Prolonged-Release Hydrogel Formulations for CPG-ODNs

Technology / Case number: #26051J
Robert Langer / Stephen Linderman / Eric Wehrenberg-Klee / Jan-Georg Rosenboom / Avik Som / Ameya Kirtane / Giovanni Traverso
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Spiral Integrated Optical Phased Arrays for Tunable Near-Field-Focusing Emission

Technology / Case number: #26247
Jelena Notaros
Technology Areas: Computer Science / Electronics & Photonics / Sensing & Imaging
Impact Areas: Connected World
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mRNA-based Myeloid Cell Stimulation Enhances Therapeutic Efficacy

Technology / Case number: #25731J
Daniel Anderson / Christopher Garris / Riddha Das / Kaelan Reed / Akash Gupta / Ralph Weissleder
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Artificial Intelligence Training Core with Coincidence Counting Unit

Technology / Case number: #25350
Jeehwan Kim / Giho Lee
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science
Impact Areas: Connected World
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Bridging Design Gaps: A Parametric Data Completion Approach With Graph-Guided Diffusion Models

Technology / Case number: #25903J
Nikos Arechiga / Matt Klenk / Frank Permenter / Chenyang Yuan / Rui Zhou / Yanxia Zhang / Faez Ahmed
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science
Impact Areas: Connected World
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Self-Righting Systems, Methods, and Related Components

Technology / Case number: #20706JQ
Robert Langer / Ester Caffarel Salvador / Niclas Roxhed / Minsoo Khang / Alex Abramson / Taylor Bensel / Giovanni Traverso
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Method for Controlling mRNA-Loaded Lipid Nanoparticles through Post-Injection and Buffer Control

Technology / Case number: #26460
Allan S. Myerson / Cedric Devos / Aniket Pradip Udepurkar / Peter Sagmeister / Richard D Braatz
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Immunotherapeutic Approaches Directed at MZB1 for Plasma Cell and B Cell Malignancies

Technology / Case number: #26513J
Jianzhu Chen / Mariateresa Fulciniti / Mehmet Samur / Elena Maroto Martin / Yingjie Zhao / Nikola Ivica / Mikhil Munshi
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Self-Assembling Drug Delivery Devices For Gastrointestinal Retention

Technology / Case number: #17002J
Robert Langer / Jiaqi Lin / Stacy Mo / Angela Diciccio / William Gates / Boris Nikolic / Phillip Eckhoff / Dean Glettig / Shiyi Zhang / Andrew Bellinger / Lowell Wood / Giovanni Traverso
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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High-Throughput Organ on a Chip System

Technology / Case number: #22328
Linda Griffith / Duncan O'Boyle / David L Trumper
Technology Areas: Biotechnology / Diagnostics
Impact Areas: Healthy Living
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A REtrievable IntravaSCUlar Implant SystEm (RESCUE) for Cell Therapy

Technology / Case number: #26283J
Robert Langer / Jong Seung Lee / Matt Murphy / SeungHo Lee / Giovanni Traverso
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Delivery Systems for Anti-Retroviral Drugs

Technology / Case number: #18813J
Robert Langer / Omar Abouzid / Ameya Kirtane / Mousa Jafari / Tyler Grant / Stacy Mo / Angela Diciccio / Dean Glettig / Shiyi Zhang / Andrew Bellinger / Giovanni Traverso
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Two-Phase Geometric Routing Protocol for LEO Satellite Networks

Technology / Case number: #26301L
Murat Yuksel / Tom Shake / Jun Sun / Collin Brady
Technology Areas: Communication Systems / Computer Science
Impact Areas: Connected World
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Strategy to Improve Genotoxic Chemotherapy using the Rev1 C-Terminal Domain

Technology / Case number: #26149
Graham Walker / Charley Gruber / Kevin Bian / Michael Hemann
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Using Gamma Sensory Entriainment to Rescue Brain Development Defects in Down Syndrome

Technology / Case number: #26448P
Li-Huei Tsai / Md Rezaul Islam / Dong Shin Park
Technology Areas: Sensing & Imaging / Therapeutics
Impact Areas: Healthy Living
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Thermally-Motivated Circuit Designs and Chip Capabilities

Technology / Case number: #26525L
Chenson Chen / Ryan Keech / Phillip Bailey / Melissa Smith / Daniel Santiago
Technology Areas: Computer Science / Electronics & Photonics / Sensing & Imaging
Impact Areas: Connected World
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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