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Using Cross-Dressing to Enhance Anti-Tumor Immune Responses

Technology / Case number: #21679
Stefani Spranger / Ellen Duong
Technology Areas: Biotechnology / Chemicals & Materials / Diagnostics / Therapeutics
Impact Areas: Healthy Living
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Single-Cell Density as A Biomarker for Drug Sensitivity

Technology / Case number: #23741J
Keith Ligon / Richard Wu / Teemu Miettinen / Sarah Ishamuddin / Kin-Hoe Chow / Scott Manalis
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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1. Methods for in Vitro Evolution of Constructs Derived from Viruses. 2. Five Mutations Derived from the in Vitro Evolution. 3. Seventeen constructs from the five mutations.

Technology / Case number: #20395H
Ron Weiss / Yingzhong Li / Darrell Irvine
Technology Areas: Biotechnology / Drug Delivery / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Nanosensors for Detecting and Imaging of Cancer Metastasis

Technology / Case number: #20490H
Liangliang Hao / Sangeeta Bhatia
Technology Areas: Biotechnology / Chemicals & Materials / Diagnostics
Impact Areas: Healthy Living
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Acute Sensitivity Testing of Cancer Samples Using Functional Cell Mass and Imaging Biomarkers or Drug Response

Technology / Case number: #21001J
Selim Olcum / Robert Kimmerling / Nicholas Calistri / Mark Stevens / Keith Ligon / Seth Malinowski / Mehdi Touat / Mark Murakami / David Weinstock / Scott Manalis
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Circular, Strained Zymogen

Technology / Case number: #21110J
Ronald Raines / Ian Windsor
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Novel Chimeric Antigen Receptor Signaling Domains Derived via Activity-based Directed Evolution

Technology / Case number: #21116
Michael Birnbaum / Taeyoon Kyung
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Optimization of Circular Single Stranded DNA using M13 Phage

Technology / Case number: #21211
Christopher Voigt / Uyanga Tsedev / Tae-Gon Cha / Angela Belcher
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Characterization and Utilization of a Subgenomic Promoter Mutant Library for Tuning Expression of Multiple Transgenes from Alphavirus Replicons

Technology / Case number: #21309
Ron Weiss / Jin Huh
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Concepts and Methods for Constructing Elastic Tissue-Hydrogel Hybrids

Technology / Case number: #21394
Kwanghun Chung / Taeyun Ku
Technology Areas: Chemicals & Materials / Diagnostics
Impact Areas: Healthy Living, Advanced Materials
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Intra-Tumoral Injection of Cytotoxic Chemotherapy-Treated Tumor Cells in Combination with Systemic Immune Checkpoint Blockade for Cancer Treatment

Technology / Case number: #21498H
Ganapathy Sriram / Lauren Milling / Darrell Irvine / Michael Yaffe
Technology Areas: Diagnostics / Therapeutics
Impact Areas: Healthy Living
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Endogenous Gene Sensing and Actuation by Placement of Non-Coding RNA after Transcriptional Termination Signals

Technology / Case number: #21520
James Collins / Ron Weiss / Jeremy Gam / Elvira Vitu / Casper Enghuus
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Anti-Human KLRB1 Monoclonal Antibodies and Uses Thereof

Technology / Case number: #21645J
Kai Wucherpfennig / Byong Ha Kang / Nathan Mathewson / Karl Wittrup
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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An Integrated and Automated Electronic System for Point-of-Care Protein Testing

Technology / Case number: #21674
Dan Wu / Joel Voldman
Technology Areas: Biotechnology / Diagnostics
Impact Areas: Healthy Living
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An Electrokinetic-based High-Throughput Concentrator for Cells, Bioparticles, and Molecules

Technology / Case number: #21685
Hyuckjin Kwon / Jongyoon Han
Technology Areas: Agriculture & Food / Biotechnology / Diagnostics
Impact Areas: Healthy Living
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Multiplexed in Vivo Disease Sensing with Nucleic Acid-Barcoded Reporters enabling CRISPR-Cas-based Detection

Technology / Case number: #21723H
Liangliang Hao / Renee Zhao / Chayanon Ngambenjawong / Sangeeta Bhatia
Technology Areas: Biotechnology / Chemicals & Materials / Diagnostics
Impact Areas: Healthy Living
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Systems and Assays for Identifying PU.1 Inhibitors

Technology / Case number: #21734P
Li-Huei Tsai / William Ralvenius / Alison Mungenast
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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An Endoribonuclease-based Incoherent Feedforward Loop for Accurate Control of Gene Expression Levels in Mammalian Cells

Technology / Case number: #21843
Ron Weiss / Ross Jones / Breanna DiAndreth / Domitilla Del Vecchio / Yili Qian
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Molecular Sensors with Modified Ligands

Technology / Case number: #22059
He Wei / Alan Jasanoff
Technology Areas: Biotechnology / Chemicals & Materials / Diagnostics
Impact Areas: Healthy Living
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TRAV-007 (Genome Sequencing) 62/790,799

Technology / Case number: #22143J
Robert Kimmerling / Mark Stevens / Keith Ligon / Scott Manalis
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools
Impact Areas: Healthy Living
License

The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

filtered: 195 results

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