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Delivery Systems for Anti-Retroviral Drugs

Technology / Case number: #18813J
Robert Langer / Omar Abouzid / Ameya Kirtane / Mousa Jafari / Tyler Grant / Stacy Mo / Angela Diciccio / Dean Glettig / Shiyi Zhang / Andrew Bellinger / Giovanni Traverso
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Using Gamma Sensory Entriainment to Rescue Brain Development Defects in Down Syndrome

Technology / Case number: #26448P
Li-Huei Tsai / Md Rezaul Islam / Dong Shin Park
Technology Areas: Sensing & Imaging / Therapeutics
Impact Areas: Healthy Living
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Rational Mutants of Bxb1 Derived from Structural Insights

Technology / Case number: #25675J
Omar Abudayyeh / Teppei Soma / Masahiro Hiraizumi / Christopher Fell / Hiroshi Nishimasu / Jonathan S. Gootenberg
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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L-SOMA: Oral Delivery of a Biologic Molecule to the Stomach Wall via a Liquid Injection

Technology / Case number: #21194QJ
Robert Langer / Andreas Vegge / Jorrit Jeroen Water / Xiaoya Lu / Mikkel Wennemoes Hvitfeld Ley / Brian Jensen / Mette Poulsen / Jesper Windum / Brian Mouridsen / Mikkel Oliver Jespersen / Morten Frederiksen / Alex Abramson / Giovanni Traverso
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Apparatus, Systems and Methods For Continuous RNA Manufacturing

Technology / Case number: #26430J
Allan S. Myerson / Marianna Sofman / Richard D Braatz
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Sensing by Control of Droplet Alignment

Technology / Case number: #19007
Timothy Manning Swager / Suchol Savagatrup / Qifan Zhang
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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Peptide-Polyanion Conjugate to Activate STING Innate Immune Signaling

Technology / Case number: #26286
Paula Hammond / Justin Kaskow
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Devices for Needless Drug Delivery in the GI tract

Technology / Case number: #21911QJ
Robert Langer / Adam Jun Bohr / Aghiad Ghazal / Drago Sticker / Cody Cleveland / Torben Sebastia Last / Yi Lu / Graham Arrick / Declan Gwynne / Sean You / Jacob Wainer / Niclas Roxhed / Giovanni Traverso
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Hardware Models of Biochemical Reaction Networks

Technology / Case number: #13076
Rahul Sarpeshkar
Technology Areas: Biotechnology / Computer Science
Impact Areas: Healthy Living
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Non-Invasive Sensory Stimulation Modifies the Microbiome-Gut-Brain Axis and Engages Insular-Vagal Circuitry

Technology / Case number: #25760P
Li-Huei Tsai / Jung Park / Ravikiran Raju / Cheng-Yi Yang / Lorenzo Bozzelli / Daniela Rodrigues Amorim
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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An Energy-Efficient, Adiabatic Electrode Stimulator with Inductive Energy Recycling and Feedback Current Regulation

Technology / Case number: #14859
Rahul Sarpeshkar / Scott Arfin
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Energy & Distribution
Impact Areas: Healthy Living
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Supramolecular PEGylation of Protein Therapeutics

Technology / Case number: #18077
Robert Langer / Eric Appel / Matthew Webber / Daniel Anderson
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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A Micropower Neural Amplifier with Adaptive Input-Referred Noise

Technology / Case number: #12586
Rahul Sarpeshkar / Woradorn Wattanapanitch / Benjamin Rapoport
Technology Areas: Biotechnology / Electronics & Photonics
Impact Areas: Healthy Living
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A Flexible and Implantable Glucose Fuel Cell

Technology / Case number: #16172L
Rahul Sarpeshkar / Michale S Fee / Benjamin Rapoport / Jakub Kedzierski / Todd Thorsen / Jeremy Muldavin
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Energy & Distribution / Sensing & Imaging
Impact Areas: Healthy Living
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Engineered Binding Proteins that Specifically Target Bacteria

Technology / Case number: #22368
Hadley Sikes / Yining Hao / Ki-Joo Sung
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Collapsible Library Design to Enable Characterization of Hyperdiverse Peptide Libraries

Technology / Case number: #26377J
Bradley L. Pentelute / Dimuthu Vithanage / Corey Johnson / John Albin / Gha Young Lee / Wayne Vuong
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Designing Single Polymer Chain Nanoparticles to Mimic Biomolecular Hydration Frustration

Technology / Case number: #25875
Alfredo Alexander-Katz / Tianyi Jin / Connor Wilson Coley
Technology Areas: Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living
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Precision Administration of Ultra-Loaded Injectable Nanocarriers (PAULINA)

Technology / Case number: #26169J
Giovanni Traverso / Cooper Konz / Yogesh Deshpande / Nabil Shalabi / Will Tritschler / SeungHo Lee / Jason Li
Technology Areas: Drug Delivery
Impact Areas: Healthy Living
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Platform for Label-Free Recording/Imaging Metabolic Activity and Status in Cells

Technology / Case number: #25931P
W. David Lee / Rebecca Zubajlo / Tatsuya Osaki / Xiang (Shawn) Zhang
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
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Fanzors are RNA-Guided Nucleases Encoded in Eukaryotic Genomes

Technology / Case number: #24942
Omar Abudayyeh / Kaiyi Jiang / Justin Lim / Jonathan S. Gootenberg
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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