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Non-Fibrotic Implantable Devices on Diverse Organs

Technology / Case number: #24648
Xuanhe Zhao / Jue Deng / Jingjing Wu / Hyunwoo Yuk
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living, Advanced Materials
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System and Methods for Noninvasive Point-of-Care Intracranial Pressure, Intracranial Compliance, and Cerebrovascular Resistance Measurement

Technology / Case number: #24678
Charles Sodini / Syed Imaduddin / Thomas Heldt
Technology Areas: Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living
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Preferential Crystallization of fullrAAVs in a Hanging Drop Crystallizer as an Alternative Method for Downstream Purification of rAAV-based Gene Therapies

Technology / Case number: #24870
Anthony Sinskey / Vivekananda Bal / Moo Sun Hong / Stacy Springs / Richard D Braatz / Paul Barone
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Implantable device to ensure stoma patency following Endoscopic Third Ventriculostomy Procedure

Technology / Case number: #24977
Ellen Roche / Jonas Sog / Gabriel Friedman / Bryce Starr / Luca Rosalia
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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Recombinant Transmembrane Domain-Deficient STING as Biomimetic Protein Carrier for cGAMP Enhanced Cancer Immunotherapy

Technology / Case number: #25012
Paula Hammond / Celestine Jia Huey Hong / Shengnan Huang / Yanpu He / Jiahe Li / Angela Belcher
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Polystyrene Coated Magnetic Beads Serving as Raman Reporter for Simultaneous Target Binding and Identification

Technology, Tangible Property / Case number: #25081
Loza Tadesse / Nikiwe Mhlanga / Jongwan Lee / Marissa Morales
Technology Areas: Biotechnology / Chemicals & Materials / Diagnostics
Impact Areas: Healthy Living
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Mechanisms for Controlled Volume Injection into a Soft Media with Concurrent Pressure Measurement

Technology / Case number: #25109
Alexander Slocum / Sarah Sams / Andre Pincot / Joseph Morales / Emily Sologuren / Brendan Unikewicz / Tal Cohen / Nevan Hanumara
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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Eye Drop Positioning Device with Haptic Feedback

Technology / Case number: #25116
Benjamin Lahner / Jesse George-Akpenyi / Carly Smith / Seung Hyeon Shim
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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Minimally Invasive Electroceutical Catheters

Technology / Case number: #22483J
Ellen Roche / Manisha Singh / Terry Steele
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living
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Using Cross-Dressing to Enhance Anti-Tumor Immune Responses

Technology / Case number: #21679
Stefani Spranger / Ellen Duong
Technology Areas: Biotechnology / Chemicals & Materials / Diagnostics / Therapeutics
Impact Areas: Healthy Living
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Gamma Entrainment using Sensory Stimuli Alleviate Cognitive Deficits and Neuroinflammation Induced by Chemotherapy Agents

Technology / Case number: #22066P
Li-Huei Tsai / TaeHyun Kim
Technology Areas: Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
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Single-Cell Density as A Biomarker for Drug Sensitivity

Technology / Case number: #23741J
Scott Manalis / Kin-Hoe Chow / Sarah Ishamuddin / Teemu Miettinen / Weida Wu / Keith Ligon
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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System and Method for Automated Ovarian Follicular Monitoring

Technology / Case number: #19173PJ
Emery N Brown / Aaron Styer / Rose Faghih
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Communication Systems / Computer Science
Impact Areas: Healthy Living
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  • Women's Health
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Locally Delivered Therapeutics and Combinations for Expedited Passage of Urinary Stones

Technology / Case number: #19454JQ
Michael Cima / Brian Eisner / Xiang Li
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Mammalian Synthetic Biology Approaches for the Precise Control of mAb N-Glycosylation (Pfizer-MIT PTM Track 2 Interim Joint Summary Document)

Technology / Case number: #19972J
Timothy K Lu / Bruno Figueroa / John Scarcelli / Jeffrey Marshall / Richard Cornell / Giyoung Jung / Michelle Chang / Leonid Gaidukov / Wen Tseng / Nevin Summers / Ron Weiss
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Enhanced Endogenous Recombination for Gene Therapy and Genetic Engineering

Technology / Case number: #20008M
Guoping Feng / Qiangge Zhang / Martin Wienisch / Tomomi Aida / Jonathan Wilde
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Overcoming Emission Photon Scattering in Wide-Field Microscopy

Technology / Case number: #20164P
Peter So / Dushan Wadduwage / Balpreet Ahluwalia / Kalen Berry / Yi Xue / Jong Kang Park / Christopher Rowlands / Elly Nedivi
Technology Areas: Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
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Advanced Architectures and Operating Principles for Electrochemical Neuro-Modulation

Technology / Case number: #20280J
Jongyoon Han / Matthew Flavin / Daniel Freeman
Technology Areas: Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living
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Gastric-Resident Devices for Gram-level Drug Delivery

Technology / Case number: #20379JQ
Robert Langer / Daniel Minahan / Taylor Bensel / Malvika Verma / Tyler Grant / Andrew Bellinger / Giovanni Traverso
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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1. Methods for in Vitro Evolution of Constructs Derived from Viruses. 2. Five Mutations Derived from the in Vitro Evolution. 3. Seventeen constructs from the five mutations.

Technology / Case number: #20395H
Darrell J Irvine / Yingzhong Li / Ron Weiss
Technology Areas: Biotechnology / Drug Delivery / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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