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Injectable, Thermogelling, Prolonged-Release Hydrogel Formulations for CPG-ODNs

New
Technology / Case number: #26051J
Giovanni Traverso / Ameya Kirtane / Robert Langer / Avik Som / Jan-Georg Rosenboom / Eric Wehrenberg-Klee / Stephen Linderman
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Self-Righting Systems, Methods, and Related Components

New
Technology / Case number: #20706JQ
Giovanni Traverso / Taylor Bensel / Alex Abramson / Minsoo Khang / Niclas Roxhed / Ester Caffarel Salvador / Robert Langer
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Methods, Procedures, and Material Compositions to Formulate Thermally Stable Solid-State Lipid Nanoparticles via Drying at Ambient Conditions

Technology / Case number: #26177
Ana Jaklenec / Robert Langer / Mina Konakovic Lukovic / Jinbi Tian / Khanh Tran / Amy Lee
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Poly(-amino ester) Microparticles for Micronutrient Fortification

Technology / Case number: #22992
Ana Jaklenec / Robert Langer / Ruiqing Xiao / Linzixuan Rhoda Zhang
Technology Areas: Agriculture & Food / Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living
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AO mRNA-LNP Stabilization

Technology / Case number: #26266
Ana Jaklenec / Robert Langer / Linzixuan Rhoda Zhang / Jooli Han / Tina Huang
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Lipid-Polymer Microparticles (mLPM) For Thermostable, Pulsatile mRNA-LNP Vaccines

Technology / Case number: #26154
Ana Jaklenec / Robert Langer / Linzixuan Rhoda Zhang / Yuting Huang
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Branched Poly(-amino esters) for the Delivery of Nucleic Acids

Technology / Case number: #20333JQ
Giovanni Traverso / Yunhua Shi / Ameya Kirtane / Grace Junyue Zhong / Daniel Reker / Robert Langer / Hyunjoon Kim / Netra Kamat / James Byrne / Gary Liu
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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A Mechanical Underwater Soft Adhesion System for Kinetic Biosensing and Intelligent Targeted Drug Delivery

Technology / Case number: #26028J
Giovanni Traverso / Ameya Kirtane / Ming Zhao / Troy Ziliang Kang / Yubin Cai
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Lipid Compositions and Methods

Technology / Case number: #25115J
Sho Toyonaga / Theresa Raimondo / Dennis Shi / Daniel Anderson
Technology Areas: Drug Delivery
Impact Areas: Healthy Living
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Synergisms between Small Molecule Boosters and LNP Formulations Uncovered using High Throughput Screening and Machine Learning

Technology / Case number: #26199J
Giovanni Traverso / Ameya Kirtane / Rajib Dey / Deepak Subramanian
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Biodegradable Lipid-Like Materials for Applications in siRNA Delivery

Technology / Case number: #15420
Kathryn Whitehead / Arturo Vegas / Yunlong Zhang / Joseph Dorkin / Robert Langer / Daniel Anderson
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
License

Compositions and Methods to Deliver RNA to Extracellular Matrix Producing Cells

Technology / Case number: #25390J
Sho Toyonaga / Theresa Raimondo / Dennis Shi / Daniel Anderson
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
License

Self- Regulated Peptide Hydrogel for Closed Loop Insulin Delivery

Technology / Case number: #15056J
Zhen Gu / Alex Aimetti / Robert Langer / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living
License

Ultrasound-Mediated Gastrointestinal Drug Delivery

Technology / Case number: #17807JQ
William Brugge / Avraham Schroeder / Giovanni Traverso / Baris Polat / Carl Schoellhammer / Robert Langer / Daniel Blankschtein
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
License

Biodegradable Polyamine-Fatty Acid Derived Lipidoids for Drug Delivery

Technology / Case number: #16367
Joseph Dorkin / Owen Fenton / Rebecca McClellan / Daniel Anderson
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
License

1,2-Aminoalcohol Lipidoids (II)

Technology / Case number: #13661Q
Kerry Mahon / Kevin Love / Christopher Levins / Kathryn Whitehead / Robert Langer / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living
License

Formulation of Polymeric Particles for Prostate Cancer Targeting

Technology / Case number: #12162J
Jianjun Cheng / Benjamin Teply / Stephen Zale / Robert Langer / Omid Farokhzad
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
License

Immune Pharmacytes: Nanoparticle-Modified Leukocytes for Immunotherapy

Technology / Case number: #13509H
Matthias Stephan / Jae Hyun (James) Moon / Anna Bershteyn / Darrell J Irvine
Technology Areas: Diagnostics / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
License

Lithium-Ion Fiber Battery

Technology / Case number: #16676
Benjamin Grena / Yoel Fink
Technology Areas: Chemicals & Materials / Drug Delivery / Energy & Distribution
Impact Areas: Healthy Living, Advanced Materials
License

Surface Binding of Nanoparticles-Based Drug Delivery to Tissue

Technology / Case number: #15731
Rohit N Karnik / Cliff Wong / Ambika Bajpayee / Alan Grodzinsky / Moungi G Bawendi
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
License

The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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