Method for High Efficiency in Vivo Gene Editing

The present disclosure relates to compositions and methods for modifying a gene sequence, and for systems for delivering such compositions. For example, the disclosure relates to modifying a gene sequence using a CRISPR-Cas9 or other nucleic acid editing system, and methods and delivery systems for achieving such gene modification, such as viral or non-viral delivery systems.

Researchers

Wen Xue / Joseph Dorkin / Hao Yin / Tyler Jacks / Daniel Anderson

Departments: David H Koch Institute for Integrative Cancer Res, Department of Chemical Engineering
Technology Areas: Biotechnology: DNA & RNA Editing / Drug Delivery: Vectors & Virus like Particles / Therapeutics: Nucleic Acids
Impact Areas: Healthy Living

  • delivery systems and kits for gene editing
    United States of America | Granted | 10,047,355
  • method for gene editing
    United States of America | Granted | 10,941,395
  • method for gene editing
    United States of America | Published application

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