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MicroRNA-based Logic Gates that Do Not Use Exogenous Proteins

Technology / Case number: #21334
Ron Weiss / Giulio Alighieri
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Synthesis and Anti-cancer Activity of Communesin Alkaloids

Technology / Case number: #21462
Mohammad Movassaghi / Matthew Pompeo / Jaime Cheah
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
License

Synthesis of Potent Epidithiodiketopiperazines Designed for Facile Derivatization

Technology / Case number: #21469
Mohammad Movassaghi / Joshua Payette / Jaime Cheah / Chase Olsson / Tony Scott
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
License

Gene Therapy in Mammalian Cells by the use of the Strand Displacement Reaction

Technology / Case number: #21486
Ron Weiss / Giulio Alighieri
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
License

An Endoribonuclease-based Incoherent Feedforward Loop for Accurate Control of Gene Expression Levels in Mammalian Cells

Technology / Case number: #21843
Ron Weiss / Ross Jones / Breanna DiAndreth / Domitilla Del Vecchio / Yili Qian
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
License

Carbon Nanoparticles for use as a Vehicle to Target and Treat Macrophages, and Macrophage RNF41 as a Molecule Essential to Switch Macrophage Phenotype

Technology / Case number: #22023
Elazer Edelman / Pedro Melgar Lesmes
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
License

Accurate Genome Editing

Technology / Case number: #21848
Timothy Lu / Shota Nakade
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
License

Simultaneous Delivery of Cancer Treatment Programs to Tumor and Immune Cells

Technology / Case number: #22351
Ron Weiss / Jin Huh / Yingzhong Li
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
License

Split Intein-based Selection for Modified Peptide Binders to SARS-CoV-2 Spike Protein

Technology / Case number: #22502
Christopher Voigt / Emerson Glassey / Andrew King
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
License

Compositions of Polypeptides for Subunit Vaccines for SARS-CoV-2

Technology / Case number: #22703
John Love / Neil Dalvie / Sergio Rodriguez
Technology Areas: Therapeutics
Impact Areas: Healthy Living
License

Identification of Genes and Mutations that Underlie Adaptation of Gut Microbes to Denovo Degradation of Oxalate

Technology / Case number: #23007
Jeff Gore / Avihu Yona
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
License

Lectin Fingerprinting for Mapping Viral Glycosylation and Identifying Neutralizing Antibodies

Technology / Case number: #22955
Laura Kiessling / Michael Wuo / Amanda Dugan
Technology Areas: Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
License

Lung-Cancer Specific T Cell Dysfunction

Technology / Case number: #23004
John Love / Stefani Spranger / Brendan Horton / Duncan Morgan / Karl Wittrup
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
License

Heme-binding Small Peptide

Technology / Case number: #23132
Graham Walker / Siva Sankari Iyer Mani Sankaran / Vigneshbabu Musuri Periasamy
Technology Areas: Therapeutics
Impact Areas: Healthy Living
License

Compounds, Compositions, and Methods of Macrocyclic Depsipeptide Antibiotics

Technology / Case number: #23104
Mohammad Movassaghi / Bradley Pentelute / Carly Schissel / Kyan D'Angelo
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
License

M13 Phage based Gene Therapy Platform (Chapter 4 of Thesis Work)

Technology / Case number: #23296
Uyanga Tsedev / Angela Belcher
Technology Areas: Biotechnology / Chemicals & Materials / Diagnostics / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
License

Protection of Next-Generation Probiotics during Processing

Technology / Case number: #23587
Chelsea Catania / Ariel Furst / Gang Fan / Pris Wasuwanich
Technology Areas: Agriculture & Food / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
License

Peptide-Encoded Libraries of Small Molecules for De Novo Drug Discovery

Technology / Case number: #23712
Bradley Pentelute / Nathalie Grob / Simon Roessler / Stephen Buchwald
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
License

Targeted Layered Lipid Nanoparticles for in Vivo Extrahepatic Gene Delivery

Technology / Case number: #24751
Namita Nabar / Tamara Dacoba / Paula Hammond
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
License

Recombinant Transmembrane Domain-Deficient STING as Biomimetic Protein Carrier for cGAMP Enhanced Cancer Immunotherapy

Technology / Case number: #25012
Jiahe Li / Yanpu He / Shengnan Huang / Celestine Jia Huey Hong / Paula Hammond / Angela Belcher
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
License

The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

filtered: 189 results

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