MicroRNA-based Logic Gates that Do Not Use Exogenous Proteins
Invention type: Technology
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Case number: #21334
The present disclosure, at least in part, relates to a miRNA based logic gate that comprises an engineered RNA carrier that comprises an nuclear export signal, a target site for a first miRNA and a pre-miRNA sequence for a second miRNA. Also provided by the disclosure are recombinant viruses (e.g., recombinant adeno-associated viruses (rAAV)) for delivery of the miRNA based logic gates.
Researchers
Departments: Department of Biological Engineering
Technology Areas: Biotechnology: Synthetic Biology / Drug Delivery: Vectors & Virus like Particles / Therapeutics: Nucleic Acids
Impact Areas: Healthy Living
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microrna-based logic gates and uses thereof
United States of America | Granted | 11,492,622 -
microrna-based logic gates and uses thereof
United States of America | Published application
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