Accurate Genome Editing
Invention type: Technology
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Case number: #21848
The disclosure provides systems, methods, and compositions for a target specific nuclease and a blunting enzyme to correct frameshift mutations for genome editing and treatment of diseases. In some embodiments, the target specific nuclease and the blunting enzyme are combined with a guide RNA and/or a microhomology-mediated end joining (MMEJ) inhibitor.
Researchers
Departments: Department of Biological Engineering
Technology Areas: Biotechnology: DNA & RNA Editing, Synthetic Biology / Therapeutics: Nucleic Acids
Impact Areas: Healthy Living
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systems, methods, and compositions for correction of
frameshift mutations
United States of America | Granted | 11,530,425 -
systems, methods, and compositions for correction of frameshift mutations
United States of America | Published application
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