Accurate Genome Editing
Invention type: Technology
/
Case number: #21848
The disclosure provides systems, methods, and compositions for a target specific nuclease and a blunting enzyme to correct frameshift mutations for genome editing and treatment of diseases. In some embodiments, the target specific nuclease and the blunting enzyme are combined with a guide RNA and/or a microhomology-mediated end joining (MMEJ) inhibitor.
Researchers
Timothy K Lu
/
Shota Nakade
Technology Areas: Biotechnology: DNA & RNA Editing, Synthetic Biology / Therapeutics: Nucleic Acids
Impact Areas: Healthy Living
-
systems, methods, and compositions for correction of frameshift mutations
United States of America | Granted | 12,146,152 -
systems, methods, and compositions for correction of
frameshift mutations
United States of America | Granted | 11,530,425
License this technology
Interested in this technology? Connect with our experienced licensing team to initiate the process.
Sign up for technology updates
Sign up now to receive the latest updates on cutting-edge technologies and innovations.