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Methods for the Treatment of Trinucleotide Repeat Expansion Disorders Associated with FAN1 activity via Targeting of FAN1 Splice Site Inhibitory Sequences

Technology / Case number: #24829
Christopher Ng / David Housman
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Instructional Materials in Support of: Set of Educational Building Blocks to Model Nucleic Acid Structures

Case number: #20438C
John Vandiver
Technology Areas: Communication Systems / Therapeutics
Impact Areas: Healthy Living, Connected World
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Lipid Compositions for Delivery of Therapeutic Agents Comprising Cationic Lipids

Technology / Case number: #23842J
Sho Toyonaga / Theresa Raimondo / Dennis Shi / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Compositions and Methods for Inhibiting Expression of the Signal Regulatory Protein Alpha Gene

Technology / Case number: #23695J
Sho Toyonaga / Theresa Raimondo / Dennis Shi / Daniel Anderson
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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New Ionizable Lipid Library Suitable for Multiple Organ Targeting Derived From High Throughput Combinatorial Synthesis and Screening

Technology / Case number: #23406
Bowen Li / Akiva Gordon / Idris Raji / Daniel Anderson
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Oleogel Drug Delivery Systems for Pediatric Applications

Technology / Case number: #22116J
Carlo Giovanni Traverso / Ameya Kirtane / Robert Langer / Aniket Wahane / Christina Karavasili
Technology Areas: Agriculture & Food / Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living, Advanced Materials
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Biodegradable Polymers for Messenger RNA Delivery to the Lung

Technology / Case number: #19314
Kevin Kauffman / James Kaczmarek / Asha Patel / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Structure-Guided Chemical Modification of Guide RNA and its Applications

Technology / Case number: #19175V
Hao Yin / Robert Langer / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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sgRNA Chemical Modification for Efficient Gene Editing

Technology / Case number: #17805V
Hao Yin / Robert Langer / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Single Administration, Multi-Dose, Multi-Therapeutic Capable Delivery Platform for Veterinary Applications

Technology / Case number: #20943J
Carlo Giovanni Traverso / Alex Abramson / Ester Caffarel Salvador / Robert Langer / Christoph Winfried Johannes Steiger / Michael Williams / Jacob Coffey / Jason Li / Miguel Jimenez / Tiffany Hua
Technology Areas: Agriculture & Food / Biotechnology
Impact Areas: Healthy Living, Advanced Materials
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Cationic Lipidoids and Their Uses for Immunotherapy

Technology / Case number: #19803
Linxian Li / Yuxuan Huang / Lei Miao / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Synthesis of Ester, Carbonate, and Carbamate-derived Novel Biodegradable Ionizable Lipids from Methyl Ricinoleate or Methyl 12-Hydroxystearate and its Applications

Technology / Case number: #23381Q
Luke Rhym / Bowen Li / Akiva Gordon / Manan manan / Jacob Witten / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Engineered Synthetic IRES with Improved and Robust Translation in Circular RNA

Technology / Case number: #25300YJ
James Collins / Katherine Ilia / Shiva Razavi / Kehan Zhang / Xiaoyu Chen / Makoto Lalwani / Yu Li / Nayoung Kim
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Relative Damping of Parallel Antennas for Sensing and Tuning

Technology / Case number: #24261
Alexander Peraire-Bueno / Anastasios Hart
Technology Areas: Agriculture & Food / Chemicals & Materials / Communication Systems / Environmental Engineering / Sensing & Imaging
Impact Areas: Healthy Living, Sustainable Future
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Systems, Devices, and Methods for Rheological Measurement of Granular Media using 3D Printed Tools

Technology / Case number: #24355
Crystal Owens / Robert Moose / Gareth McKinley
Technology Areas: Agriculture & Food / Industrial Engineering & Automation
Impact Areas: Healthy Living, Advanced Materials
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Selective Reduction of Tobacco Specific Nitrosamines and Related Methods

Technology / Case number: #18718
Trevor Hatton / Xiao Su / Lev Bromberg
Technology Areas: Agriculture & Food / Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living
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Wireless Chemical Dosimeters Including Chemical Hazard Badges or Ionic Liquid SWCNT Composites for Wireless Chemical Sensing With a Reader and RFID Tags

Technology / Case number: #18692
Joseph Azzarelli / Rong Zhu / Timothy Swager
Technology Areas: Agriculture & Food / Chemicals & Materials / Communication Systems / Sensing & Imaging
Impact Areas: Healthy Living, Advanced Materials
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A New Approach to Cooling and Refrigeration with Zero Global Warming Potential

Technology / Case number: #23078
Asegun Henry / Mehdi Pishahang / Andrew Rohskopf / Qingzi Zhu
Technology Areas: Agriculture & Food / Chemicals & Materials / Environmental Engineering / Industrial Engineering & Automation
Impact Areas: Healthy Living, Sustainable Future, Advanced Materials
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Device and Method for Isolation and Detection of Soluble or Particulate Analytes from Complex Background Matrices

Technology / Case number: #23246
Rohit Karnik / Krithika Ramchander / Emily Hanhauser / Mary Strawser / Chun Man Chow
Technology Areas: Agriculture & Food / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living, Sustainable Future
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Materials for Extracting Toxins from Tobacco

Technology / Case number: #24058
Ruqiang Lu / Timothy Swager
Technology Areas: Agriculture & Food / Chemicals & Materials
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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