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Ingestible Chemical Energy Harvesting System with Extended Lifetime

Technology / Case number: #23174
Giovanni Traverso / So-Yoon Yang / Jason Li
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Energy & Distribution / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Engineering a Swine Macro-Organ Colorectal Cancer Platform to Combat Transport-Induced Chemotherapy Resistance

Technology / Case number: #22864JQ
Robert Langer / Daniel Reker / Vance Soares / Yunhua Shi / Giovanni Traverso
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Cellular Backpacks for Drug Delivery Across the Blood-Brain Barrier

Technology / Case number: #18547J
Robert Cohen / Natalya Klyachko / Yuling Zhao / Matthew Haney / Elena Batrakova / Roberta Polak / Michael F Rubner
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Pupil Engineering Method to Enhance the Signal of the Real-time non-invasive Particle Size Distribution Probe in Powders and During Mixing, Drying, Blending, and Milling Processes

Technology / Case number: #24521
George Barbastathis / Ajinkya Pandit / Zhen Guo / Qihang Zhang / Richard D Braatz / Allan S. Myerson
Technology Areas: Chemicals & Materials / Industrial Engineering & Automation / Sensing & Imaging
Impact Areas: Advanced Materials
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Electrochemical CO2 Conversion Architecture

Technology / Case number: #24598
Kripa K Varanasi / Simon Rufer
Technology Areas: Chemicals & Materials / Energy & Distribution / Environmental Engineering
Impact Areas: Sustainable Future, Advanced Materials
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Oleogel Drug Delivery Systems for Pediatric Applications

Technology / Case number: #22116J
Robert Langer / Christina Karavasili / Aniket Wahane / Ameya Kirtane / Giovanni Traverso
Technology Areas: Agriculture & Food / Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living, Advanced Materials
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Nucleotide Depletion as Differentiation Therapy in the Treatment of Cancer

Technology / Case number: #21131J
Matthew Vander Heiden / Frances Diehl / David Sykes / Peggy Hsu
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Tissue Platform and Machine Learning Algorithm for Drug-Drug Transporter Interaction Discovery

Technology / Case number: #21883J
Robert Langer / Daniel Reker / Vance Soares / Yunhua Shi / Giovanni Traverso
Technology Areas: Biomaterials & Bioelectronics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Biodegradable Polymers for Messenger RNA Delivery to the Lung

Technology / Case number: #19314
Daniel Anderson / Asha Patel / James Kaczmarek / Kevin Kauffman
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Structure-Guided Chemical Modification of Guide RNA and its Applications

Technology / Case number: #19175V
Robert Langer / Hao Yin / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Derivation of Enteroendocrine Cells and Insulin Expressing Cells

Technology / Case number: #18445J
Robert Langer / Xiaolei Yin / Jeffrey Michael Karp
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Photosensitized-Photoactive Materials and Methods for Making and Using the Same

Technology / Case number: #17987J
Gareth McKinley / Gibum Kwon / Mohammad Gondal / Kripa K Varanasi
Technology Areas: Chemicals & Materials
Impact Areas: Advanced Materials
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sgRNA Chemical Modification for Efficient Gene Editing

Technology / Case number: #17805V
Robert Langer / Hao Yin / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Microbial Production of Alpha-Substituted 3-Hydroxy Acids from Glucose

Technology / Case number: #25163
Kristala L Jones Prather / K'yal Bannister
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Ionizable Lipids for Messenger RNA Delivery

Technology, Tangible Property / Case number: #24861
Daniel Anderson / Idris Raji / Jacob Witten
Technology Areas: Chemicals & Materials / Drug Delivery / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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A Generalizable, High-Throughput Method to Rapidly add Chemical Moieties to a Small Molecule Library

Technology / Case number: #22196J
Angela Koehler / Chia-fu Chang / Christina Woo / Sebastian Pomplun / Catherine Henry / Jasmin Kruell / Brice Curtin
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Synthesis of Ester, Carbonate, and Carbamate-derived Novel Biodegradable Ionizable Lipids from Methyl Ricinoleate or Methyl 12-Hydroxystearate and its Applications

Technology / Case number: #23381Q
Daniel Anderson / Jacob Witten / rajith manan / Akiva Gordon / Bowen Li / Luke Rhym
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Method of Broadband Phase Shifting for Quantitative Phase Microscopy

Technology / Case number: #21459L
William Hubbard
Technology Areas: Chemicals & Materials / Electronics & Photonics
Impact Areas: Advanced Materials
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Method for Fabricating Li-rich Solid Electrolyte and Electrode Films

Technology / Case number: #20457J
Jennifer Lilia Marguerite Rupp / Inigo Garbayo / Andreas Nenning / Michal Struzik / Reto Pfenninger
Technology Areas: Chemicals & Materials / Energy & Distribution
Impact Areas: Advanced Materials
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Synthesis and Application of Light Management with Thermochromic Hydrogel Microparticles

Technology / Case number: #20597J
Xuanlai Fang / Shien-Ping Feng / Chang Liu / Xinhao Li
Technology Areas: Chemicals & Materials / Environmental Engineering
Impact Areas: Sustainable Future, Advanced Materials
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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