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Overcoming Emission Photon Scattering in Wide-Field Microscopy

Technology / Case number: #20164P
Peter So / Dushan Wadduwage / Balpreet Ahluwalia / Kalen Berry / Yi Xue / Jong Kang Park / Christopher Rowlands / Elly Nedivi
Technology Areas: Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
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Circular, Strained Zymogen

Technology / Case number: #21110J
Ronald T Raines / Ian Windsor
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Arterial Wall Characterization in Optical Coherence Tomography Imaging

Technology / Case number: #21209
Elazer R Edelman / Lambros Anthanasiou / Max Olender
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
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Optimization of Circular Single Stranded DNA using M13 Phage

Technology / Case number: #21211
Angela Belcher / Tae-Gon Cha / Uyanga Tsedev / Christopher Voigt
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Emboli Detection Methods to Identify Stroke Mechanism or Stroke Risk in Susceptible Adults and Children

Technology, Software / Case number: #21233J
Thomas Heldt / Barry Kussman / Kerri LaRovere / Syed Imaduddin
Technology Areas: Biotechnology / Computer Science
Impact Areas: Healthy Living
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Characterization and Utilization of a Subgenomic Promoter Mutant Library for Tuning Expression of Multiple Transgenes from Alphavirus Replicons

Technology / Case number: #21309
Ron Weiss / Jin Huh
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Multi-Input miRNA Sensing with Constitutive ERNs to Regulate Multi-Output Gene Expression in Mammalian Cells

Technology / Case number: #23123
Ron Weiss / Lei Wang / Wenlong Xu / Erez Pery / Deepak Mishra
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Lipid Nanoparticles for Drug Delivery to Microglia in the Brain

Technology / Case number: #23156P
Robert Langer / William Ralvenius / Julia Bonner / Jason Andresen / Joel Blanchard / Owen Fenton / Li-Huei Tsai
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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M13 Phage based Gene Therapy Platform (Chapter 4 of Thesis Work)

Technology / Case number: #23296
Angela Belcher / Uyanga Tsedev
Technology Areas: Biotechnology / Chemicals & Materials / Diagnostics / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Targeted Layered Lipid Nanoparticles for in Vivo Extrahepatic Gene Delivery

Technology / Case number: #24751
Paula Hammond / Tamara Dacoba / Namita Nabar
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Pollen-Like Microstructures

Technology / Case number: #24869
Benedetto Marelli / Muchun Liu
Technology Areas: Agriculture & Food / Chemicals & Materials
Impact Areas: Sustainable Future, Advanced Materials
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Preferential Crystallization of fullrAAVs in a Hanging Drop Crystallizer as an Alternative Method for Downstream Purification of rAAV-based Gene Therapies

Technology / Case number: #24870
Anthony Sinskey / Vivekananda Bal / Moo Sun Hong / Stacy Springs / Richard D Braatz / Paul Barone
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Medical Recordkeeping Microneedles

Technology / Case number: #24923
Robert Langer / Yang Liu / Jooli Han / Maria Kanelli / Ana Jaklenec / Fredo Durand (he/him/his)
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Implantable device to ensure stoma patency following Endoscopic Third Ventriculostomy Procedure

Technology / Case number: #24977
Ellen Roche / Jonas Sogbadji / Gabriel Friedman / Bryce Starr / Luca Rosalia
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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Recombinant Transmembrane Domain-Deficient STING as Biomimetic Protein Carrier for cGAMP Enhanced Cancer Immunotherapy

Technology / Case number: #25012
Paula Hammond / Celestine Jia Huey Hong / Shengnan Huang / Yanpu He / Jiahe Li / Angela Belcher
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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In Solution Monoclonal Polony Generation on Inorganic Nanoparticle

Technology / Case number: #25039
Ashwin Gopinath / Emily Wu / Nayan Agarwal
Technology Areas: Chemicals & Materials / Diagnostics / Drug Discovery and Research Tools
Impact Areas: Healthy Living, Advanced Materials
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Polystyrene Coated Magnetic Beads Serving as Raman Reporter for Simultaneous Target Binding and Identification

Technology, Tangible Property / Case number: #25081
Loza Tadesse / Nikiwe Mhlanga / Jongwan Lee / Marissa Morales
Technology Areas: Biotechnology / Chemicals & Materials / Diagnostics
Impact Areas: Healthy Living
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Mechanisms for Controlled Volume Injection into a Soft Media with Concurrent Pressure Measurement

Technology / Case number: #25109
Alexander Slocum / Sarah Sams / Andre Pincot / Joseph Morales / Emily Sologuren / Brendan Unikewicz / Tal Cohen / Nevan Hanumara
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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Eye Drop Positioning Device with Haptic Feedback

Technology / Case number: #25116
Benjamin Lahner / Jesse George-Akpenyi / Carly Smith / Seung Hyeon Shim
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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Replacing Synthetic Fertilizers by Engineering Cereal-Associated Nitrogen-Fixing Bacteria to Release Urea

Technology / Case number: #25157
Christopher Voigt / Phillip Clauer
Technology Areas: Agriculture & Food / Biotechnology
Impact Areas: Sustainable Future
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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