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STING Agonist Delivery by Lipid Nanodiscs for Tumor Immunotherapy

Technology / Case number: #21441HJ
Darrell J Irvine / Masanori Okaniwa / Eric Dane
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Synthesis of Potent Epidithiodiketopiperazines Designed for Facile Derivatization

Technology / Case number: #21469
Mo Movassaghi / Tony Scott / Chase Olsson / Jaime Cheah / Joshua Payette
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Solid-State Electrolytes from Hydroboration of Rubber

Technology / Case number: #21696
Yang Shao-Horn / Megan Hill / Sipei Li / Teruhiko Saito / Jeffrey Lopez / Jeremiah A. Johnson
Technology Areas: Chemicals & Materials / Energy & Distribution
Impact Areas: Advanced Materials
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Multiplexed in Vivo Disease Sensing with Nucleic Acid-Barcoded Reporters enabling CRISPR-Cas-based Detection

Technology / Case number: #21723H
Sangeeta Bhatia / Chayanon Ngambenjawong / Renee Zhao / Liang Hao
Technology Areas: Biotechnology / Chemicals & Materials / Diagnostics
Impact Areas: Healthy Living
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Molecular Memory Retrieval by Position-based Addressing

Technology / Case number: #21829
Tyson Shepherd
Technology Areas: Biotechnology / Chemicals & Materials / Computer Science
Impact Areas: Connected World
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Crosslinked Hydrocarbon Fragments and Methods of Use Thereof

Technology / Case number: #21909
Jeremiah A. Johnson / Keith Husted / Peyton Shieh / Wenxu Zhang
Technology Areas: Chemicals & Materials
Impact Areas: Sustainable Future, Advanced Materials
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Cheaper, Environmentally Friendly, and Sustainable Biofuel Production through Yeast System

Technology / Case number: #21974
Angela Belcher / Shalmalee Pandit
Technology Areas: Biotechnology / Chemicals & Materials
Impact Areas: Sustainable Future
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Melanin-Peptide-based Photonic Materials

Technology / Case number: #22001
Christopher Voigt / Disheng Lee
Technology Areas: Chemicals & Materials / Electronics & Photonics
Impact Areas: Sustainable Future, Advanced Materials
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Carbon Nanoparticles for use as a Vehicle to Target and Treat Macrophages, and Macrophage RNF41 as a Molecule Essential to Switch Macrophage Phenotype

Technology / Case number: #22023
Elazer R Edelman / Pedro Melgar Lesmes
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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A Dynamic Soft Robotic Heart Model Combining Biohybrid Materials

Technology / Case number: #22057J
Xuanhe Zhao / Christopher Nguyen / Clara Park / Ellen Roche / Hyunwoo Yuk
Technology Areas: Biotechnology / Chemicals & Materials / Industrial Engineering & Automation
Impact Areas: Healthy Living, Advanced Materials
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Precision Delivery of Multi-Scale Payloads to Tissue-Specific Targets in Plants

Technology / Case number: #22192
Benedetto Marelli / Yunteng Cao
Technology Areas: Agriculture & Food / Chemicals & Materials
Impact Areas: Sustainable Future
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Soft Neuroprosthetic Hand

Technology / Case number: #22255J
Xuanhe Zhao / Guoying Gu / Xiangyang Zhu / Haipeng Xu / Ningbin Zhang / Shaoting Lin
Technology Areas: Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living
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Remoldable and Self-Healing Thermoset Materials

Technology / Case number: #22307
Jeremiah A. Johnson / Samantha Kristufek / Christopher Brown / Keith Husted / Peyton Shieh
Technology Areas: Chemicals & Materials
Impact Areas: Advanced Materials
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Locally Delivered Therapeutics and Combinations for Expedited Passage of Urinary Stones

Technology / Case number: #19454JQ
Michael Cima / Brian Eisner / Xiang Li
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Advanced Architectures and Operating Principles for Electrochemical Neuro-Modulation

Technology / Case number: #20280J
Jongyoon Han / Matthew Flavin / Daniel Freeman
Technology Areas: Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living
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Gastric-Resident Devices for Gram-level Drug Delivery

Technology / Case number: #20379JQ
Robert Langer / Daniel Minahan / Taylor Bensel / Malvika Verma / Tyler Grant / Andrew Bellinger / Giovanni Traverso
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Nanosensors for Detecting and Imaging of Cancer Metastasis

Technology / Case number: #20490H
Sangeeta Bhatia / Liang Hao
Technology Areas: Biotechnology / Chemicals & Materials / Diagnostics
Impact Areas: Healthy Living
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PROTAC Derivatives with Functional Handles for Chemical Conjugation/Modification

Technology / Case number: #20788J
Jeremiah A. Johnson / Aiden Wang / Michael Agius / Irene Ghobrial / Alexandre Detappe / Hung Nguyen / Yivan Jiang
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Immunostimulatory Nanoparticle Adjuvants

Technology / Case number: #20798HJ
Darrell J Irvine / Shane Crotty / Yu Kato / Murillo Silva
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Structures with Complex Geometries and Controlled Porosity in Micrometer to Meter Dimensions Produced at Large Scale

Technology / Case number: #21002J
Yoel Fink / Ian Tafel / Dena Shahriari / Zi Jie Gabriel Loke / Polina Anikeeva
Technology Areas: Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living, Advanced Materials
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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