Dynamic Nuclear Polarization with Rigid Biradicals

The present invention relates to the field of organic chemistry and in particular to organic free radicals used as polarizing agents in the technique of Dynamic Nuclear Polarization (DNP), which involves transferring the polarization of electron spins to the nuclei of a compound whose Nuclear Magnetic Resonance (NMR) is being observed. It concerns Dinitroxide-type Biradical polarizing agents characterized by a rigid linkage between the aminoxyl groups of said nitroxide units. This particular structure enables, at low temperatures and high fields, optimal transfer of polarization and optimal enhancement of NMR/MAS signals of the polarized nuclei of the compound studied.

Researchers

Robert Griffin / Paul Tordo / Yoh Matsuki / Thorsten Maly / Olivier Ouari / Hakim Karoui / Francois Le Moigne

Departments: Department of Chemistry
Technology Areas: Biotechnology: Sensors & Monitoring / Sensing & Imaging: Chemical & Radiation Sensing
Impact Areas: Healthy Living

  • dinitroxide-type biradical compounds optimized for dynamic nuclear polarization (dnp)
    United States of America | Granted | 9,035,054
  • dynamic nuclear polarization with rigid biradicals
    European Patent Convention | Granted | 0
  • dynamic nuclear polarization with rigid biradicals
    Liechtenstein | Granted | 0

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