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Injectable, Thermogelling, Prolonged-Release Hydrogel Formulations for CPG-ODNs

New
Technology / Case number: #26051J
Giovanni Traverso / Ameya Kirtane / Robert Langer / Avik Som / Jan-Georg Rosenboom / Eric Wehrenberg-Klee / Stephen Linderman
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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A Simple Watermark for Language Model

New
Technology / Case number: #25701
Elchanan Mossel
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML)
Impact Areas: Connected World
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Artificial Intelligence Training Core with Coincidence Counting Unit

New
Technology / Case number: #25350
Jeehwan Kim / Giho Lee
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science
Impact Areas: Connected World
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Bridging Design Gaps: A Parametric Data Completion Approach With Graph-Guided Diffusion Models

New
Technology / Case number: #25903J
Nikos Arechiga / Faez Ahmed / Yanxia Zhang / Rui Zhou / Chenyang Yuan / Frank Permenter / Matt Klenk
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science
Impact Areas: Connected World
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Self-Righting Systems, Methods, and Related Components

New
Technology / Case number: #20706JQ
Giovanni Traverso / Taylor Bensel / Alex Abramson / Minsoo Khang / Niclas Roxhed / Ester Caffarel Salvador / Robert Langer
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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A Method for Hierarchical Time Series Reconciliation via Learning the Optimal Projection

Technology / Case number: #26179J
Georgia Perakis / Pin-Yu Chen / Yada Zhu / Asterios Tsiourvas / Wei Sun
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science / Sensing & Imaging
Impact Areas: Connected World
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Methods, Procedures, and Material Compositions to Formulate Thermally Stable Solid-State Lipid Nanoparticles via Drying at Ambient Conditions

Technology / Case number: #26177
Ana Jaklenec / Robert Langer / Mina Konakovic Lukovic / Jinbi Tian / Khanh Tran / Amy Lee
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Poly(-amino ester) Microparticles for Micronutrient Fortification

Technology / Case number: #22992
Ana Jaklenec / Robert Langer / Ruiqing Xiao / Linzixuan Rhoda Zhang
Technology Areas: Agriculture & Food / Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living
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AO mRNA-LNP Stabilization

Technology / Case number: #26266
Ana Jaklenec / Robert Langer / Linzixuan Rhoda Zhang / Jooli Han / Tina Huang
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Optical Ising Machine and Optical Convolutional Neural Networks

Technology / Case number: #19700
Scott Skirlo / Yichen Shen / Tena Dubcek Varga / Li Jing / Charles Roques-Carmes / Hengameh Bagherianlemraski / Marin Soljacic
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Communication Systems / Sensing & Imaging
Impact Areas: Connected World
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Lipid-Polymer Microparticles (mLPM) For Thermostable, Pulsatile mRNA-LNP Vaccines

Technology / Case number: #26154
Ana Jaklenec / Robert Langer / Linzixuan Rhoda Zhang / Yuting Huang
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Branched Poly(-amino esters) for the Delivery of Nucleic Acids

Technology / Case number: #20333JQ
Giovanni Traverso / Yunhua Shi / Ameya Kirtane / Grace Junyue Zhong / Daniel Reker / Robert Langer / Hyunjoon Kim / Netra Kamat / James Byrne / Gary Liu
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
License

Correlated Transformer: A New Deep Learning Architecture for Multivariate Time Series

Technology / Case number: #26332J
Lam Nguyen / Quang Nguyen / Subhro Das
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML)
Impact Areas: Connected World
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Scale-Cascaded Coalescence

Technology / Case number: #15750L
Sai Ravela
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Sensing & Imaging
Impact Areas: Connected World
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A Mechanical Underwater Soft Adhesion System for Kinetic Biosensing and Intelligent Targeted Drug Delivery

Technology / Case number: #26028J
Giovanni Traverso / Ameya Kirtane / Ming Zhao / Troy Ziliang Kang / Yubin Cai
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Method to Improve the Image Quality of Positron Emission Tomography When Using Non-Standard Isotopes Based on Triple Coincidences

Technology / Case number: #16135
Shivang Dave / Vicente Parot / Eduardo Lage / Joaquin Herraiz
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Communication Systems / Electronics & Photonics / Sensing & Imaging
Impact Areas: Healthy Living
License

Lipid Compositions and Methods

Technology / Case number: #25115J
Sho Toyonaga / Theresa Raimondo / Dennis Shi / Daniel Anderson
Technology Areas: Drug Delivery
Impact Areas: Healthy Living
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A Single Fibre Computer Enables Textile Networks and Distributed Inference

Technology / Case number: #26084
Zi Jie Gabriel Loke / Henry Cheung / Nikhil Gupta / Syamantak Payra / Yoel Fink
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biomaterials & Bioelectronics / Biotechnology / Chemicals & Materials / Electronics & Photonics
Impact Areas: Healthy Living, Connected World
License

Synergisms between Small Molecule Boosters and LNP Formulations Uncovered using High Throughput Screening and Machine Learning

Technology / Case number: #26199J
Giovanni Traverso / Ameya Kirtane / Rajib Dey / Deepak Subramanian
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
License

Biodegradable Lipid-Like Materials for Applications in siRNA Delivery

Technology / Case number: #15420
Kathryn Whitehead / Arturo Vegas / Yunlong Zhang / Joseph Dorkin / Robert Langer / Daniel Anderson
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
License

The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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