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Systems and Methods for Computational Discovery of Microstructured Composites with Optimized Trade-off between Strength and Toughness

Technology / Case number: #23354
Wojciech Matusik / Beichen Li / Wan Shou
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Chemicals & Materials / Industrial Engineering & Automation
Impact Areas: Uncharted Frontiers, Advanced Materials
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Machine Learning for the Discovery of Nanomaterial-based Molecular Recognition

Technology / Case number: #23691
Michael S. Strano / Nicholas Renegar / Xun Gong / Retsef Levi
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Chemicals & Materials / Sensing & Imaging
Impact Areas: Healthy Living, Advanced Materials
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Functionalization of MiniHA with Lauric Acid

Technology / Case number: #20135
Bradley D. Olsen / Yun Jung Yang / Lavinia Popescu / Sieun Kim / Allie Obermeyer
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Thermogelling Nanoemulsions for Pharmaceutical Manufacturing

Technology / Case number: #22768
Patrick Doyle / Liang-Hsun Chen
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Data-Efficient Photorealistic 3D Holography using Layered Depth Images and Deep Double Phase Encoding

Technology / Case number: #23071
Wojciech Matusik / Liang Shi
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Communication Systems / Sensing & Imaging
Impact Areas: Uncharted Frontiers, Connected World
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Compounds, Compositions, and Methods of Macrocyclic Depsipeptide Antibiotics

Technology / Case number: #23104
Mo Movassaghi / Kyan D'Angelo / Carly Schissel / Bradley L. Pentelute
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Heme-binding Small Peptide

Technology / Case number: #23132
Graham Walker / Vigneshbabu Musuri Periasamy / Siva Sankari Iyer Mani Sankaran
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Lipid Nanoparticles for Drug Delivery to Microglia in the Brain

Technology / Case number: #23156P
Robert Langer / William Ralvenius / Julia Bonner / Jason Andresen / Joel Blanchard / Owen Fenton / Li-Huei Tsai
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Small Molecules to Improve Myelination in Alzheimer's Disease and APOE4 Carriers

Technology / Case number: #23168P
Li-Huei Tsai / Matheus Victor / Audrey Effenberger / Djuna von Maydell / Leyla Akay / Jose Davila Velderrain / Joel Blanchard / Manolis Kellis
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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M13 Phage based Gene Therapy Platform (Chapter 4 of Thesis Work)

Technology / Case number: #23296
Angela Belcher / Uyanga Tsedev
Technology Areas: Biotechnology / Chemicals & Materials / Diagnostics / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Using Anti-Inflammatory Drugs To Enhance The Neuroprotective Effects Of Non-Invasive Gamma Stimulation

Technology / Case number: #23402P
Li-Huei Tsai / Julia Bonner / Vanesa Fernandez Avalos / Chinnakkaruppan Adaikkan
Technology Areas: Sensing & Imaging / Therapeutics
Impact Areas: Healthy Living
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Surgical Cautery Artifact Removal from Electrodermal Activity Data

Technology / Case number: #23525PJ
Emery N Brown / Sandya Subramanian / Riccardo Barbieri
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology
Impact Areas: Healthy Living
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Protection of Next-Generation Probiotics during Processing

Technology / Case number: #23587
Chelsea Catania / Pris Wasuwanich / Gang Fan / Ariel Furst
Technology Areas: Agriculture & Food / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Nucleic Acid-Conjugated Polymeric Nanoparticles for Gene Therapy

Technology / Case number: #23628JQ
Natalie Artzi / Alexander M Cryer / Pere Dosta Pons
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Engineered Alum-binding SARS-CoV-2 Immunogens

Technology / Case number: #23632H
Darrell J Irvine / Kristen Rodrigues / Sergio Rodriguez / Neil Dalvie / J. Christopher Love
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Peptide-Encoded Libraries of Small Molecules for De Novo Drug Discovery

Technology / Case number: #23712
Stephen Buchwald / Simon Roessler / Nathalie Grob / Bradley L. Pentelute
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Slow Delivery of Antigen and Adjuvant Plus A Delayed Boost for Unexpected Immunogenicity

Technology / Case number: #23762HJ
Darrell J Irvine / Shane Crotty
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Method and Apparatus for Inferring Elevated Pulmonary Capillary Wedge Pressures from Single-Lead Electrocardiogram Telemetry Data

Technology, Software / Case number: #23955J
Collin M Stultz / Eugene Pomerantsev / Ridwan Alam / Daphne Schlesinger
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living
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Intranasal amphiphile-protein conjugate vaccine

Technology / Case number: #23991H
Darrell J Irvine / Brittany Hartwell
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Activatable Antimicrobial Peptides and Uses Thereof

Technology / Case number: #24024H
Sangeeta Bhatia / Chayanon Ngambenjawong
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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