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Overcoming Emission Photon Scattering in Wide-Field Microscopy

Technology / Case number: #20164P
Peter So / Dushan Wadduwage / Balpreet Ahluwalia / Kalen Berry / Yi Xue / Jong Kang Park / Christopher Rowlands / Elly Nedivi
Technology Areas: Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
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Advanced Architectures and Operating Principles for Electrochemical Neuro-Modulation

Technology / Case number: #20280J
Jongyoon Han / Matthew Flavin / Daniel Freeman
Technology Areas: Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living
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Gastric-Resident Devices for Gram-level Drug Delivery

Technology / Case number: #20379JQ
Robert Langer / Daniel Minahan / Taylor Bensel / Malvika Verma / Tyler Grant / Andrew Bellinger / Giovanni Traverso
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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1. Methods for in Vitro Evolution of Constructs Derived from Viruses. 2. Five Mutations Derived from the in Vitro Evolution. 3. Seventeen constructs from the five mutations.

Technology / Case number: #20395H
Darrell J Irvine / Yingzhong Li / Ron Weiss
Technology Areas: Biotechnology / Drug Delivery / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Nanosensors for Detecting and Imaging of Cancer Metastasis

Technology / Case number: #20490H
Sangeeta Bhatia / Liang Hao
Technology Areas: Biotechnology / Chemicals & Materials / Diagnostics
Impact Areas: Healthy Living
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A Multimodal Metric for Tracking Nociception Under Anesthesia

Technology / Case number: #20522J
Emery N Brown / Sandya Subramanian / Riccardo Barbieri
Technology Areas: Biotechnology / Computer Science
Impact Areas: Healthy Living
License

Leveraging Device-arterial Coupling to Determine Cardiac and Vascular State

Technology / Case number: #20558J
Elazer R Edelman / Ahmad El Katerji / Quing Tan / Noam Josephy / Sonya Sanat Bhavsar / Steven Keller / Brian Chang
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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Structures with Complex Geometries and Controlled Porosity in Micrometer to Meter Dimensions Produced at Large Scale

Technology / Case number: #21002J
Yoel Fink / Ian Tafel / Dena Shahriari / Zi Jie Gabriel Loke / Polina Anikeeva
Technology Areas: Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living, Advanced Materials
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Using Cross-Dressing to Enhance Anti-Tumor Immune Responses

Technology / Case number: #21679
Stefani Spranger / Ellen Duong
Technology Areas: Biotechnology / Chemicals & Materials / Diagnostics / Therapeutics
Impact Areas: Healthy Living
License

Single-Cell Density as A Biomarker for Drug Sensitivity

Technology / Case number: #23741J
Scott Manalis / Kin-Hoe Chow / Sarah Ishamuddin / Teemu Miettinen / Weida Wu / Keith Ligon
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Minimally Invasive Electroceutical Catheters

Technology / Case number: #22483J
Ellen Roche / Manisha Singh / Terry Steele
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living
License

Multi-Input miRNA Sensing with Constitutive ERNs to Regulate Multi-Output Gene Expression in Mammalian Cells

Technology / Case number: #23123
Ron Weiss / Lei Wang / Wenlong Xu / Erez Pery / Deepak Mishra
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
License

M13 Phage based Gene Therapy Platform (Chapter 4 of Thesis Work)

Technology / Case number: #23296
Angela Belcher / Uyanga Tsedev
Technology Areas: Biotechnology / Chemicals & Materials / Diagnostics / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Surgical Cautery Artifact Removal from Electrodermal Activity Data

Technology / Case number: #23525PJ
Emery N Brown / Sandya Subramanian / Riccardo Barbieri
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology
Impact Areas: Healthy Living
License

Engineered Alum-binding SARS-CoV-2 Immunogens

Technology / Case number: #23632H
Darrell J Irvine / Kristen Rodrigues / Sergio Rodriguez / Neil Dalvie / J. Christopher Love
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Peptide-Encoded Libraries of Small Molecules for De Novo Drug Discovery

Technology / Case number: #23712
Stephen Buchwald / Simon Roessler / Nathalie Grob / Bradley L. Pentelute
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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High-Throughput and High-Precision Measurement of Single-Cell Density

Technology / Case number: #23740
Scott Manalis / Teemu Miettinen / Weida Wu
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
License

Intracellular Molecular Recording and Memory via Protein Self-Assembly

Technology / Case number: #23746HPM
Edward Stuart Boyden / Changyang Linghu
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
License

Multifunctional Microelectronics Fibers as Implantable Bioelectronic Interfaces for Central and Peripheral Neuromodulation

Exclusively Licensed Technology / Case number: #23751JQ
Polina Anikeeva / Diego Bohórquez / Laura Rupprecht / Atharva Sahasrabudhe / Tural Khudiyev
Technology Areas: Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living

Activity-based Cell Sorting

Technology / Case number: #23765HJ
Sangeeta Bhatia / Ava Soleimany / Jesse Kirkpatrick
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools
Impact Areas: Healthy Living
License

The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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