Multi-Input miRNA Sensing with Constitutive ERNs to Regulate Multi-Output Gene Expression in Mammalian Cells
Invention type: Technology
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Case number: #23123
Provided herein are sequestrons for detecting an miRNA profile indicative of a cell state and expressing an output molecule in cells having such an miRNA profile. Also provided are methods of using sequestrons provided herein.
Researchers
Ron Weiss
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Deepak Mishra
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Erez Pery
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Wenlong Xu
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Lei Wang
Departments: Department of Biological Engineering
Technology Areas: Biotechnology: Sensors & Monitoring, Synthetic Biology / Drug Discovery and Research Tools: Cell Interrogation
Impact Areas: Healthy Living
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multi-input mirna sensing with constitutive erns to regulate multi-output gene expression in mammalian cells
United States of America | Published application -
multi-input mirna sensing with constitutive erns to regulate multi-output gene expression in mammalian cells
European Patent Convention | Published application -
multi-input mirna sensing with constitutive erns to regulate multi-output gene expression in mammalian cells
Israel | Pending -
multi-input mirna sensing with constitutive erns to regulate multi-output gene expression in mammalian cells
Japan | Published application
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