Overcoming Emission Photon Scattering in Wide-Field Microscopy
Systems and methods herein provide improved, high-throughput multiphoton imaging of thick samples with reduced emission scattering. The systems and methods use structured illumination to modify the excitation light. A reconstruction process can be applied to the resulting images to recover image information free of scattering. The disclosed systems and methods provide high throughput, high signal-to-noise ratio, and high resolution images that are depth selective.
Researchers
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systems and methods to reduce scattering in temporal focusing multiphoton microscopy
United States of America | Granted | 11,562,584
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