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Patient-Specific Benchtop Beating Heart Simulator for Recreating Left Atrial Biomechanics and Hemodynamics for LAA Closure and HFpEF Intervention Testing

Technology / Case number: #25761
Ellen Roche / Manisha Singh / Keegan Mendez
Technology Areas: Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living
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A Mechanical Underwater Soft Adhesion System for Kinetic Biosensing and Intelligent Targeted Drug Delivery

Technology / Case number: #26028J
Giovanni Traverso / Yubin Cai / Troy Ziliang Kang / Ming Zhao / Ameya Kirtane
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Lipid Compositions and Methods

Technology / Case number: #25115J
Daniel Anderson / Dennis Shi / Theresa Raimondo / Sho Toyonaga
Technology Areas: Drug Delivery
Impact Areas: Healthy Living
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A Single Fibre Computer Enables Textile Networks and Distributed Inference

Technology / Case number: #26084
Yoel Fink / Syamantak Payra / Nikhil Gupta / Henry Cheung / Zi Jie Gabriel Loke
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biomaterials & Bioelectronics / Biotechnology / Chemicals & Materials / Electronics & Photonics
Impact Areas: Healthy Living, Connected World
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Method to Release Alcohol Reporters for Profiling Disease Characteristics in Breath

Technology / Case number: #25202H
Sangeeta Bhatia / Shih-Ting (Christine) Wang / Melodi Anahtar
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
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Synergisms between Small Molecule Boosters and LNP Formulations Uncovered using High Throughput Screening and Machine Learning

Technology / Case number: #26199J
Giovanni Traverso / Deepak Subramanian / Rajib Dey / Ameya Kirtane
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Biodegradable Lipid-Like Materials for Applications in siRNA Delivery

Technology / Case number: #15420
Robert Langer / Joseph Dorkin / Yunlong Zhang / Arturo Vegas / Kathryn Whitehead / Daniel Anderson
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Compositions and Methods to Deliver RNA to Extracellular Matrix Producing Cells

Technology / Case number: #25390J
Daniel Anderson / Dennis Shi / Theresa Raimondo / Sho Toyonaga
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
License

Self- Regulated Peptide Hydrogel for Closed Loop Insulin Delivery

Technology / Case number: #15056J
Robert Langer / Alex Aimetti / Zhen Gu / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living
License

Biodegradable Polyamine-Fatty Acid Derived Lipidoids for Drug Delivery

Technology / Case number: #16367
Daniel Anderson / Rebecca McClellan / Owen Fenton / Joseph Dorkin
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
License

1,2-Aminoalcohol Lipidoids (II)

Technology / Case number: #13661Q
Robert Langer / Kathryn Whitehead / Kevin Love / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living
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Formulation of Polymeric Particles for Prostate Cancer Targeting

Technology / Case number: #12162J
Robert Langer / Omid Farokhzad
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Wearable Monitor and Feedback Device for Knee Osteoarthritis

Technology / Case number: #17056TE
Hugh M Herr / Madeleine Abromowitz
Technology Areas: Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living
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Seizure Detection and Prediction Apparatus

Technology / Case number: #15454J
Anantha Chandrakasan / Muhammad Bin Altaf / Dina El-Damak / Long Yan / Jerald Yoo / Ali Shoeb
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Communication Systems
Impact Areas: Healthy Living
License

Immune Pharmacytes: Nanoparticle-Modified Leukocytes for Immunotherapy

Technology / Case number: #13509H
Darrell J Irvine
Technology Areas: Diagnostics / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Engineered Probiotics for Urinary Cancer Diagnosis

Technology / Case number: #15881HJ
Sangeeta Bhatia / Jeff Hasty / Arthur Prindle / Tal Danino
Technology Areas: Biomaterials & Bioelectronics / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
License

Pulse Detection from Head Motions in Video

Technology / Case number: #16417
John Guttag / Guha Balakrishnan / Fredo Durand (he/him/his)
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Communication Systems
Impact Areas: Healthy Living
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Lithium-Ion Fiber Battery

Technology / Case number: #16676
Yoel Fink / Benjamin Grena
Technology Areas: Chemicals & Materials / Drug Delivery / Energy & Distribution
Impact Areas: Healthy Living, Advanced Materials
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A Sensor Array Based on Nanowire Field Effect Transistors (NWFETs) for Remote Radiation Sensing

Technology / Case number: #16090
Robert Langer / Virginia Spanoudaki / Daniel Anderson
Technology Areas: Biomaterials & Bioelectronics / Sensing & Imaging
Impact Areas: Healthy Living
License

Surface Binding of Nanoparticles-Based Drug Delivery to Tissue

Technology / Case number: #15731
Alan Grodzinsky / Ambika Bajpayee / Cliff Wong / Rohit N Karnik / Moungi G Bawendi
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
License

The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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