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Tunable Structure of Biodegradable Silk-Based Microcapsules for Soluble and Insoluble Payload Delivery

Technology / Case number: #23764J
Benedetto Marelli / Yagmur Yegin / Bernd Oschmann / Rupert Konradi / Ophelie Zeyons / Henning Urch / Pierre-Eric Millard / Muchun Liu
Technology Areas: Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living, Advanced Materials
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System, Material and Methods to Improve the Performance of Wireless Sensing in Health Monitoring Applications

Technology / Case number: #20713
Sanjay Emani Sarma / Pankhuri Sen / Alexandre Armengol Urpi / Sai Nithin Redd Kantareddy / Joshua Siegel / Rahul Bhattacharyya
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Communication Systems
Impact Areas: Healthy Living
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Method for Zero Phase-Lag Real-Time Computation of Hilbert Transform and Analytic Signal

Technology / Case number: #18073TEJ
Edward Stuart Boyden / David Wang / Nir Grossman
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
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Vibrating Ingestible BioElectronic Stimulator (VIBES)

Technology / Case number: #23759JQ
Robert Langer / Amro Alshareef / Shriya Sruthi Srinivasan / Giovanni Traverso
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Closed-Loop Noninvasive Brain Stimulation with Simultaneous Imaging to Control Cerebrospinal Fluid Flow in Humans

Technology / Case number: #25482
Laura D. Lewis / Joshua Levitt
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Computer Science / Sensing & Imaging
Impact Areas: Healthy Living
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Ingestible Electronics Integrated with Flexible Measurement Electrodes for Gastrointestinal Bioelectric Sensing

Technology / Case number: #23241J
Robert Langer / George Selsing / Adam Gierlach / So-Yoon Yang / Sean You / Giovanni Traverso
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Computer Science
Impact Areas: Healthy Living, Advanced Materials
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A Boronic Acid Based CoPhMoRe Polymer for Glucose Detection Using Near Infrared Fluorescent Single Walled Carbon Nanotube Nanosensors

Technology / Case number: #16761
Michael S. Strano / Jiyoung Ahn / Thomas McNicholas
Technology Areas: Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living
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A Handheld Closed-Loop Automatic Insulin Delivery System

Technology / Case number: #22018J
Giovanni Traverso / Canchen Li / Erin Raftery / Sean You / Hen Wei Huang
Technology Areas: Biotechnology / Communication Systems / Drug Delivery
Impact Areas: Healthy Living
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Novel Ionizable Lipids Suitable For Lipid Nanoparticle Delivery of mRNA to Lung and Nasal Epithelium, As Well As Lung Endothelium

Technology / Case number: #23594Q
Daniel Anderson / Idris Raji / Jacob Witten / Allen Jiang / Luke Rhym
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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New Ionizable Lipid Library Suitable for Multiple Organ Targeting Derived From High Throughput Combinatorial Synthesis and Screening

Technology / Case number: #23406
Daniel Anderson / Idris Raji / Akiva Gordon / Bowen Li
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Engineering a Swine Macro-Organ Colorectal Cancer Platform to Combat Transport-Induced Chemotherapy Resistance

Technology / Case number: #22864JQ
Robert Langer / Daniel Reker / Vance Soares / Yunhua Shi / Giovanni Traverso
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Closed-Loop Ingestible Robot for Radiation and Chemical Sensing

Technology / Case number: #22735
Giovanni Traverso / James Byrne / Hen Wei Huang
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Industrial Engineering & Automation / Sensing & Imaging
Impact Areas: Healthy Living, Uncharted Frontiers
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Endovascular Injectable Stents for Cardiovascular Drug Delivery

Technology / Case number: #22578J
Giovanni Traverso / Mohammed Chowdhury / Mazen Albaghdadi / Sahab Babaee
Technology Areas: Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living, Advanced Materials
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Ingestible Electronic Pills for Hormone Modulation

Technology / Case number: #22427
Giovanni Traverso / James McRae / Khalil Ramadi
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Oleogel Drug Delivery Systems for Pediatric Applications

Technology / Case number: #22116J
Robert Langer / Christina Karavasili / Aniket Wahane / Ameya Kirtane / Giovanni Traverso
Technology Areas: Agriculture & Food / Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living, Advanced Materials
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Machine Learning for the Design of Cancer Vaccine Adjuvants

Technology / Case number: #21680J
Robert Langer / Netra Kamat / Hyunjoon Kim / Lewis Scott Jones / Daniel Reker / Ameya Kirtane / Giovanni Traverso
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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Flexible Electronics for Analyte Detection

Technology / Case number: #21994JQ
Robert Langer / Luca Di Tizio / Sean You / Hen Wei Huang / Giovanni Traverso
Technology Areas: Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living
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Tissue Platform and Machine Learning Algorithm for Drug-Drug Transporter Interaction Discovery

Technology / Case number: #21883J
Robert Langer / Daniel Reker / Vance Soares / Yunhua Shi / Giovanni Traverso
Technology Areas: Biomaterials & Bioelectronics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Crystalline and Amorphous Formulations Used to Deliver Anti-Fibrotic (and other) Compounds in Conjunction with Implanted Materials (Cells/Devices)

Technology / Case number: #18287J
Robert Langer / Shady Farah / Joshua Doloff / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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A Fully Implantable, Autonomous Closed-Loop System Capable of Long-Term Vital Signs Monitoring and Performing Lifesaving Treatment

Technology / Case number: #23387J
Anantha Chandrakasan / Ian Ballinger / Tom Kerssemakers / Peter Chai / Saurav Maji / SeungHo Lee / Hen Wei Huang / Giovanni Traverso
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Computer Science / Energy & Distribution
Impact Areas: Healthy Living, Advanced Materials
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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