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Thiol-yne Mediated Synthesis of Multi-Tailed Lipids for siRNA Delivery

Technology / Case number: #15846
Kevin Love / Akinleye Alabi / Robert Langer / Daniel Anderson
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Injectable Hydrogel and Uses Thereof

Technology / Case number: #16662J
Yizhou Dong / Benjamin Tang / Kun Xue / Matthew Webber / Omid Veiseh / Weiheng Wang / Eric Appel / Robert Langer / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living, Advanced Materials
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Reversible Covalent Modification for Improving Protein Delivery

Technology / Case number: #16581HQ
Li Tang / Darrell J Irvine
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Multilayer Porous Hydrogel for Robust Sensing of Macromolecules with Florescent Carbon Nanotube Sensors

Technology / Case number: #15892
Michael S. Strano / Nigel Reuel
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Chemicals & Materials / Sensing & Imaging
Impact Areas: Healthy Living
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Self-Assembled (Poly-(L-Glutamic Acid-PEG-Drug)-PLGA Micelles for Multistage Nanoparticle Delivery System

Technology / Case number: #14877J
Cliff Wong / Dai Fukumura / Moungi G Bawendi / Rakesh K. Jain
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Tissue Specific Delivery of Interfering RNA

Technology / Case number: #13947H
Yin Ren / Sangeeta Bhatia
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Novel Cancer Therapeutics through Brain Stimulation

Technology / Case number: #25655TE
Deblina Sarkar / Ishaq Khan / Ray Lee / Monochura Saha
Technology Areas: Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living
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Controlled Assembly of Lipid-Based Nanoparticles from Surfactant Micelles

Technology / Case number: #25418H
Ivan Pires / Darrell J Irvine / Paula Hammond
Technology Areas: Biotechnology / Drug Delivery
Impact Areas: Healthy Living, Advanced Materials
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System and Method to Predict Exertional Heat Stroke from Torso-Worn Sensor

Technology / Case number: #21970LJ
Jeffrey Palmer / Brian Telfer / Jim Williamson / Lara Weed / Mark Buller / Rebecca Fellin / Joseph Seay
Technology Areas: Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living
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Vaccine Targeting to Mucosal Lymphoid Tissues in the Gastrointestinal Tract

Technology / Case number: #25463H
Ozgun Kocabiyik / Darrell J Irvine
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Biomarkers Derived from Neurophysiological Computational Modeling

Technology / Case number: #18088L
Satrajit Ghosh / Jeffrey Palmer / Christopher Smalt / Brian Helfer / Daryush Mehta / Jim Williamson / Gregory Ciccarelli / Joseph Perricone / Thomas Quatieri
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living
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Estimating Contractile Reserve using a Mechanical Circulatory Support Device

Technology / Case number: #25817J
Elazer R Edelman / Steven Keller / Ahmad El Katerji / Jerald Curran
Technology Areas: Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living
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Wearable Bioadhesive Ultrasound Elastography

Technology / Case number: #25587J
Xuanhe Zhao / Hsiao-Chuan Liu / Yushun Zeng / Qifa Zhou
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
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Micro-Invasive Neural System for Delivering Antiseizure Medications to the Epileptic Focus for the Treatment of Refractory Epilepsy

Technology / Case number: #25721J
Michael Cima / Max Cotler / Hannah Jackson / Cameron Metcalf / Karen Wilcox / Peter West
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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Scalable and High throughput Assembly of Layer-by-Layer Nanoparticles

Technology / Case number: #25554H
Ivan Pires / Darrell J Irvine / Paula Hammond
Technology Areas: Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living, Advanced Materials
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Zwitterionic Polymer Functionalized Lipid Nanoparticles for Delivery of mRNA

Technology / Case number: #24662
Robert Langer / Allen Jiang / Sushil Lathwal / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Robocap

Technology / Case number: #24836J
Giovanni Traverso / Shriya Sruthi Srinivasan / Robert Langer / Amro Alshareef
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Modular MicroRNA Expression from Self-Replicating RNA (Replicons)

Technology / Case number: #25464
Ron Weiss / Tea Crnkovic
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Bioadhesive Pacing Lead

Technology / Case number: #25301J
Xuanhe Zhao / Hyunwoo Yuk / Jue Deng / Christoph Nabzdyk
Technology Areas: Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living
License

Non-Surgical Biomedical Implants

Technology / Case number: #25352TE
Deblina Sarkar / Shubham Yadav
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living, Uncharted Frontiers, Advanced Materials
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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