Production of Stable Non-Polyadenylated RNAs
Invention type: Technology
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Case number: #15860
The invention relates in aspects to hybrid RNAs lacking a poly-A tail and nucleic acid vectors for expressing the RNA. The hybrid RNAs in some instances have a 3′ terminal stabilizing triple helical structure. Related methods for expressing said RNAs in vivo and in vitro are also disclosed.
Researchers
Phillip Sharp
/
Jeremy Wilusz
Departments: Office of the Institute Professors
Technology Areas: Biotechnology: DNA & RNA Editing / Drug Delivery: Vectors & Virus like Particles
Impact Areas: Healthy Living
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production of stable non-polyadenylated rnas
United States of America | Granted | 10,946,035 -
production of stable non-polyadenylated rnas
United States of America | Granted | 9,717,749
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