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Single-Cell RNA Sequencing Using Click-Chemistry

Technology / Case number: #20396
Phillip Sharp / D.B.Jay Mahat
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Device and Method for Imaging Shortwave Infrared Autofluorescence

Technology / Case number: #18527J
Moungi G Bawendi / Marianne Aellen / Yi Zheng / Klaus Van Leyen / Jessica Carr / Oliver Bruns
Technology Areas: Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living
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Biodegradable Polymers for Messenger RNA Delivery to the Lung

Technology / Case number: #19314
Daniel Anderson / Asha Patel / James Kaczmarek / Kevin Kauffman
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Structure-Guided Chemical Modification of Guide RNA and its Applications

Technology / Case number: #19175V
Robert Langer / Hao Yin / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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sgRNA Chemical Modification for Efficient Gene Editing

Technology / Case number: #17805V
Robert Langer / Hao Yin / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Hybrid Materials with Living Cells and Tough Hydrogels

Technology / Case number: #18548
Timothy K Lu / Tzu-Chieh Tang / Xinyue Liu / Eleonore Tham / Xuanhe Zhao
Technology Areas: Biomaterials & Bioelectronics / Chemicals & Materials / Diagnostics / Therapeutics
Impact Areas: Healthy Living
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Pooled Screening Identifies Genomic Features (Biomarkers) Modulating Nanoparticle-Cell Interactions

Technology / Case number: #22785J
Paula Hammond / Joelle Straehla / Natalie Boehnke / Angela Koehler
Technology Areas: Diagnostics / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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Cationic Lipidoids and Their Uses for Immunotherapy

Technology / Case number: #19803
Daniel Anderson / Lei Miao / Yuxuan Huang / Linxian Li
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Ultrastructural Membrane Expansion Microscopy

Technology / Case number: #25088HM
Edward Stuart Boyden / Tay Won Shin
Technology Areas: Chemicals & Materials / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living
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Biodegradable Lipids and Formulations for Intramuscular, In Vitro, and Ex Vivo Transfection of mRNA

Technology / Case number: #23969J
Daniel Anderson / Kaelan Reed / Akash Gupta / Arnab Rudra
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Near and Shortwave Infrared Polymethine Dyes

Technology / Case number: #19474
Timothy Manning Swager / Justin Caram / Ellen Sletten
Technology Areas: Diagnostics / Electronics & Photonics / Sensing & Imaging
Impact Areas: Healthy Living
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Method for Point-of-use Testing for Bacteriological Water Contamination in Resource-Limited Environments

Technology / Case number: #19080
Anastasios John Hart / Sydney Beasley / Chintan Vaishnav / Michael Bono / Emily Hanhauser / Rohit N Karnik
Technology Areas: Biotechnology / Diagnostics / Environmental Engineering / Sensing & Imaging
Impact Areas: Healthy Living
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Near Infrared Fluorescent Biosensors for Steroid Hormones

Technology / Case number: #21434
Michael S. Strano / Song Wang / Naveed Bakh / Michael Lee
Technology Areas: Biotechnology / Chemicals & Materials / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living
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Quantitative Ultra-sensitive Detection of Biological Species

Technology / Case number: #21467
Timothy Manning Swager / Cassandra Zentner / Zachary Nelson / Jie Li / Kosuke Yoshinaga / Suchol Savagatrup
Technology Areas: Agriculture & Food / Chemicals & Materials / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living, Advanced Materials
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Extending Fluorescent Assays In Vivo for Biomedical Sensing: Wavelength Modulation Spectroscopy

Technology / Case number: #22003
Michael S. Strano / Naveed Bakh / Volodymyr Koman
Technology Areas: Biotechnology / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living
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Organelle-Selective Gene Delivery and Expression in the Chloroplast in planta using Chitosan-Complexed Single-Walled Carbon Nanotube Carriers

Technology / Case number: #20537
Michael S. Strano / Tedrick Salim Lew / Seonyeong Kwak
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living, Sustainable Future
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Scalable and Safe Quantum Dot Precursor

Technology / Case number: #20834
Moungi G Bawendi / Matthias Ginterseder / Daniel Franke
Technology Areas: Chemicals & Materials / Diagnostics / Electronics & Photonics / Sensing & Imaging
Impact Areas: Healthy Living, Advanced Materials
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Device and Method for Isolation and Detection of Target Cells/Particles from Complex Background Matrices

Technology / Case number: #20847
Rohit N Karnik / Mary Strawser / Michael Bono / Emily Hanhauser
Technology Areas: Diagnostics
Impact Areas: Healthy Living
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Device and Method for Isolation and Detection of Soluble or Particulate Analytes from Complex Background Matrices

Technology / Case number: #23246
Rohit N Karnik / Chun Man Chow / Mary Strawser / Emily Hanhauser / Krithika Ramchander
Technology Areas: Agriculture & Food / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living, Sustainable Future
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Antibody-Free Rapid Detection of SARS-CoV-2 Proteins Using Corona Phase Molecular Recognition (CoPhMoRe)

Technology / Case number: #23605
Michael S. Strano / Jianqiao Leslie Cui / Sungyun Yang / Xiaojia Jin / Sooyeon Cho / Xun Gong
Technology Areas: Chemicals & Materials / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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