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Ingestible Electronics Integrated with Flexible Measurement Electrodes for Gastrointestinal Bioelectric Sensing

Technology / Case number: #23241J
Robert Langer / George Selsing / Adam Gierlach / So-Yoon Yang / Sean You / Giovanni Traverso
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Computer Science
Impact Areas: Healthy Living, Advanced Materials
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Methods of Enhancing the Survival of Introduced Genes and Organisms

Technology / Case number: #22105TE
Kevin Esvelt / Sarah Vitak
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Predictor of Deletions after Targeted Chromosome Cleavage

Technology / Case number: #21045
David K Gifford / Jonathan Hsu / Max Shen
Technology Areas: Biotechnology / Computer Science
Impact Areas: Healthy Living, Connected World
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A Boronic Acid Based CoPhMoRe Polymer for Glucose Detection Using Near Infrared Fluorescent Single Walled Carbon Nanotube Nanosensors

Technology / Case number: #16761
Michael S. Strano / Jiyoung Ahn / Thomas McNicholas
Technology Areas: Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living
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Formulated, Biodegradable Polymeric Nanoparticles for Nucleic Acid Delivery to Non-Liver Targets

Technology / Case number: #19802
Daniel Anderson / Luke Rhym / Asha Patel / James Kaczmarek / Kevin Kauffman
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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High-Throughput Screens for Exploring Biological Functions of Microscale Biological Systems

Technology / Case number: #19737JR
Paul Blainey / Navpreet Ranu
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Novel Ionizable Lipids Suitable For Lipid Nanoparticle Delivery of mRNA to Lung and Nasal Epithelium, As Well As Lung Endothelium

Technology / Case number: #23594Q
Daniel Anderson / Idris Raji / Jacob Witten / Allen Jiang / Luke Rhym
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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New Ionizable Lipid Library Suitable for Multiple Organ Targeting Derived From High Throughput Combinatorial Synthesis and Screening

Technology / Case number: #23406
Daniel Anderson / Idris Raji / Akiva Gordon / Bowen Li
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Single-Cell RNA Sequencing Using Click-Chemistry

Technology / Case number: #20396
Phillip Sharp / D.B.Jay Mahat
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Engineering a Swine Macro-Organ Colorectal Cancer Platform to Combat Transport-Induced Chemotherapy Resistance

Technology / Case number: #22864JQ
Robert Langer / Daniel Reker / Vance Soares / Yunhua Shi / Giovanni Traverso
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Closed-Loop Ingestible Robot for Radiation and Chemical Sensing

Technology / Case number: #22735
Giovanni Traverso / James Byrne / Hen Wei Huang
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Industrial Engineering & Automation / Sensing & Imaging
Impact Areas: Healthy Living, Uncharted Frontiers
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Endovascular Injectable Stents for Cardiovascular Drug Delivery

Technology / Case number: #22578J
Giovanni Traverso / Mohammed Chowdhury / Mazen Albaghdadi / Sahab Babaee
Technology Areas: Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living, Advanced Materials
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Ingestible Electronic Pills for Hormone Modulation

Technology / Case number: #22427
Giovanni Traverso / James McRae / Khalil Ramadi
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Flexible Electronics for Analyte Detection

Technology / Case number: #21994JQ
Robert Langer / Luca Di Tizio / Sean You / Hen Wei Huang / Giovanni Traverso
Technology Areas: Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living
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Tissue Platform and Machine Learning Algorithm for Drug-Drug Transporter Interaction Discovery

Technology / Case number: #21883J
Robert Langer / Daniel Reker / Vance Soares / Yunhua Shi / Giovanni Traverso
Technology Areas: Biomaterials & Bioelectronics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Biodegradable Polymers for Messenger RNA Delivery to the Lung

Technology / Case number: #19314
Daniel Anderson / Asha Patel / James Kaczmarek / Kevin Kauffman
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Structure-Guided Chemical Modification of Guide RNA and its Applications

Technology / Case number: #19175V
Robert Langer / Hao Yin / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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sgRNA Chemical Modification for Efficient Gene Editing

Technology / Case number: #17805V
Robert Langer / Hao Yin / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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A Fully Implantable, Autonomous Closed-Loop System Capable of Long-Term Vital Signs Monitoring and Performing Lifesaving Treatment

Technology / Case number: #23387J
Anantha Chandrakasan / Ian Ballinger / Tom Kerssemakers / Peter Chai / Saurav Maji / SeungHo Lee / Hen Wei Huang / Giovanni Traverso
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Computer Science / Energy & Distribution
Impact Areas: Healthy Living, Advanced Materials
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Tough Hydrogel Pills Inflating 100 Times in Volume Within 10 Min

Technology / Case number: #20059
Xuanhe Zhao / Xinyue Liu / German Parada Hernandez / Hyunwoo Yuk / Shaoting Lin
Technology Areas: Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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