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Generation of Specialized, High-Value Cells and Tissues from Human Induced Pluripotent Stem Cells by Recapitulating Early Embryogenesis Using Gata Factor-Induced Endoderm

Technology, Tangible Property / Case number: #16205
Ron Weiss / Mohammad Reza Ebrahimkhani / Patrick Guye
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Method for High Efficiency in Vivo Gene Editing

Technology / Case number: #17117H
Tyler Jacks / Hao Yin / Joseph Dorkin / Wen Xue / Daniel Anderson
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Programmable Drug Delivery Profiles of Tumor-Targeted Bacteria

Technology / Case number: #15818H
Sangeeta Bhatia / Tal Danino
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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High-Throughput Screening Metabolic Flux Biosensor

Technology / Case number: #16813JW
Gerald Fink / Jose Avalos / Gregory Stephanopoulos
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Epigenetic Mechanisms Re-Establish Access to Long-Term Memory After Neuronal Loss

Technology / Case number: #12467HPBJ
Stuart Schreiber / Stephen Haggarty / Li-Huei Tsai / Andre Fischer / Weiping Tang
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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In Vivo Targeting of T-Cells with Antibody- and Cytokine Conjugated Liposomes

Technology / Case number: #16405H
Darrell J Irvine / Brandon Kwong / Yuan Zhang / Yiran Zheng
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Tough, Thermoreversible Hydrogels from the Arrested Phase Separation of Elastin-Like Polypeptides: Simple, Injectable, Biocompatible Substrates for the Engineering of Load-Bearing Tissues

Technology / Case number: #17430
Bradley D. Olsen / Reginald Avery / Matthew Glassman
Technology Areas: Biomaterials & Bioelectronics / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Thermally-Gelling Injectable Hydrogel Composites for Therapeutic Delivery

Technology / Case number: #25878
Patrick Doyle / Talia Zheng
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Synthesis and Anticancer Activity of Agelastatin Alkaloids

Technology / Case number: #16512J
Mo Movassaghi / Paul Hergenrother
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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  • Women's Health
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A Single-Walled Carbon Nano-Tube/Chitosan Hydrogel Array for the Label-Free, Optical Detection of Protein-Protein Interactions

Technology / Case number: #14201
Michael S. Strano / Nigel Reuel / Jin Ho Ahn / Paul Barone / Jong Ho Kim
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Sensing & Imaging / Therapeutics
Impact Areas: Healthy Living
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Cystic Fibrosis Correction with Programmable Genomic Editing

Technology / Case number: #24666
Omar Abudayyeh / Christopher Fell / Matthew Yarnall / Jonathan S. Gootenberg
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Compositions for Enhancing Esophageal Drug Retention and Absorption

Technology / Case number: #25238JQ
Giovanni Traverso / Christina Karavasili
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Formulations for Stabilizing Lactobacillus and Bifidobacterium Strains

Technology / Case number: #25723J
Giovanni Traverso / Isaac Tucker / Kimberley Biggs / Mairead Heavey / Samantha Bozorgzadeh / Matt Murphy / Christina Karavasili
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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mRNA Subunit Vaccines for African Swine Fever

Technology / Case number: #25930
Jianzhu Chen / Fangfeng Yuan / Junru Cui
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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HDL Probe 2

Technology / Case number: #15787JR
Monty Krieger / Patrick Falloon / Andrew Germain / Partha Nag / Willmen Youngsaye / Sivaraman Dandapani / Miao Yu / Christopher Dockendorff / Benito Munoz / Thomas Nieland
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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The Site-Specific Incorporation of a Redox-Active and Chemically-Reactive Amino Acid into Proteins in E. Coli

Technology / Case number: #12973J
JoAnne Stubbe / Lital Alfonta / Clement Tsz Chan / Mohammad Seyedsayamdost / Jianming Xie / Peter Schultz
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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HDL Probe (BI-2012/024)

Technology / Case number: #15788JR
Monty Krieger / Timothy Lewis / Chris Dockndorff / Patrick Falloon / Partha Nag / Willmen Youngsaye / Sivaraman Dandapani / Miao Yu / Benito Munoz / Thomas Nieland
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Design and Applications of a Set of Antibody Cysteine Variants

Technology / Case number: #13713JQ
Bernhardt Trout / Veysel Kayser / Vladimir Voynov / Bernhard Helk / Naresh Chennamsetty
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Amino-Amidine Based Polymers for Drug Delivery

Technology / Case number: #14057Q
Robert Langer / Joseph Dorkin / Arturo Vegas / Kathryn Whitehead / Daniel Anderson
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Covalently Functionalized Hydrogels on Oxygen Permeable Membranes for Stable, Scalable, and Xeno Free Growth of Undifferentiated Human Embryonic Stem Cells

Technology / Case number: #16162
Clark Colton / Amanda Diienno / Anna Coclite / Karen Gleason
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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