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"Click-Type" Modifications of Peptides via SNAr Reaction of Thiols with Fluorinated Aromatic Molecules

Exclusively Licensed Technology / Case number: #15765
Stephen Buchwald / Chi Zhang / Yekui Zou / Alexander Spokoyny / Bradley L. Pentelute
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living

End-Modified Poly(b-amino ester)s

Non-Exclusively Licensed Technology / Case number: #12049Q
Robert Langer / Gregory Zugates / Andreas Zumbuehl / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
License

Uses of Chemicals to Modulate GSK-3B/B-Catenin Signaling for Treatment of Bipolar Disorder and Other Brain Disorders

Technology / Case number: #13480BJ
Stephen Haggarty / Michael Lewis / Edward Holson / Qian Pan / Joshua Ketterman / Tracey Petryshen / Daniel Fass
Technology Areas: Diagnostics / Therapeutics
Impact Areas: Healthy Living
License

Novel Full Spectrum Anti-Dengue Antibody

Exclusively Licensed Technology / Case number: #16643
Ram Sasisekharan / Kannan Tharakaraman
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living

Peptide and Protein Modification to Afford Sox-Based Kinase Sensors

Exclusively Licensed Technology / Case number: #12133Q
Barbara Imperiali / Dora Carrico-Moniz / Elvedin Lukovic
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living

Molecular Determinants of Human Adaptation of H5N1 Influenza A Virus Hemagglutinin

Exclusively Licensed Technology / Case number: #14274
Rahul Raman / Kannan Tharakaraman / Karthik Viswanathan / Ram Sasisekharan
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living

Combination Therapies for Prostate and Breast Cancer with Abiraterone

Exclusively Licensed Technology / Case number: #16690Q
Michael Yaffe / Jesse C Patterson
Technology Areas: Therapeutics
Impact Areas: Healthy Living

Bortezomib Prodrugs

Exclusively Licensed Technology / Case number: #20771JQ
Jeremiah A. Johnson / Irene Ghobrial / Alexandre Detappe / Hung Nguyen / Yivan Jiang / Paiman Ghoroghchian
Technology Areas: Therapeutics
Impact Areas: Healthy Living

Molecular Design of Antibodies with Enhanced Stability

Non-Exclusively Licensed Technology / Case number: #13229J
Bernhardt Trout / Veysel Kayser / Vladimir Voynov / Bernhard Helk / Naresh Chennamsetty
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
License

Collagen-Localized Immunomodulatory Molecules for Cancer Immunotherapy

Exclusively Licensed Technology / Case number: #20867
Karl Dane Wittrup / Magnolia Chinn / Allison Sheen / Joseph Palmeri / Noor Momin
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living

Single Injection Delivery Systems

Exclusively Licensed Technology / Case number: #16746JQ
Robert Langer / Kevin McHugh / James Norman / Stephany Tzeng / Thanh Nguyen / William Gates / Boris Nikolic / Phillip Eckhoff / Lowell Wood / Ana Jaklenec / No Inventor
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living

Hybrid Microcapsules Containing Islets and Anti-Inflammatory Drugs for Diabetes Therapy

Exclusively Licensed Technology / Case number: #14504JQ
Robert Langer / Joshua Cohen / Karolina Siniakowicz / Jennifer Hollister-Lock / Thuy Dang / Gordon Weir / Daniel Anderson
Technology Areas: Biomaterials & Bioelectronics / Therapeutics
Impact Areas: Healthy Living

Synthetic Oncolytic LNP-Replicon RNA for Cancer Immunotherapy

Exclusively Licensed Technology / Case number: #21306HJQ
Darrell J Irvine / Noor Momin / Yingzhong Li / Yizhou Dong / Ron Weiss / Karl Dane Wittrup
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living

Minimally Invasive Methods for Sealing Tissues with a Bioadhesive patch

Exclusively Licensed Technology / Case number: #22665J
Xuanhe Zhao / Sarah Wu / Christoph Nabzdyk / Hyunwoo Yuk
Technology Areas: Biomaterials & Bioelectronics / Therapeutics
Impact Areas: Healthy Living

Light-gated Ion Channels with Fast Kinetics and High Sensitivity

Exclusively Licensed Technology / Case number: #16950TEJ
Gane Wong / Adam Cohen / Daniel Hochbaum / Yongku Cho / Nathan Klapoetke / Edward Stuart Boyden / Brian Chow
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Sensing & Imaging / Therapeutics
Impact Areas: Healthy Living

A Dual-Barreled Medical Injector

Exclusively Licensed Technology / Case number: #23529
Kripa K Varanasi / Vishnu Jayaprakash
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living

Compositions and Methods for Promoting Hemostasis and other Physiological Activities.

Exclusively Licensed Technology / Case number: #12061J
Gerald Schneider / Yu Xiang Liang / David Tay / Kwok-Fai So / Rutledge Ellis-Behnke
Technology Areas: Biomaterials & Bioelectronics / Therapeutics
Impact Areas: Healthy Living

Rational Design of Affinity Improvement of Dengue 4e11 Antibody

Exclusively Licensed Technology / Case number: #15783
Ram Sasisekharan / Kannan Tharakaraman / Luke Robinson
Technology Areas: Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living

Anti-Dengue Virus NS1 Protein Monoclonal Antibodies

Non-Exclusively Licensed Technology / Case number: #18262J
Lee Gehrke / Helena de Puig Guixe / Irene Bosch / Jose Gomez-Marquez / Kimberly Hamad-Schifferli
Technology Areas: Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
License

An Amphiphilic Mimotope Vaccine to Enhance FDA-Approved Anti-CD19 CAR T Therapy

Exclusively Licensed Technology / Case number: #22096H
Darrell J Irvine / Benjamin Cossette / Leyuan Ma / Naveen Mehta / Karl Dane Wittrup
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living

The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

filtered: 331 results

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