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Design and Applications of a Set of Antibody Cysteine Variants

Technology / Case number: #13713JQ
Naresh Chennamsetty / Bernhard Helk / Vladimir Voynov / Veysel Kayser / Bernhardt Trout
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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RNA Engineering for CRISPR Synthetic Circuits and Endogenous Regulation

Technology / Case number: #16876
Timothy K Lu / Samuel Perli / Lior Nissim
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Amino-Amidine Based Polymers for Drug Delivery

Technology / Case number: #14057Q
Kathryn Whitehead / Arturo Vegas / Joseph Dorkin / Robert Langer / Daniel Anderson
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Covalently Functionalized Hydrogels on Oxygen Permeable Membranes for Stable, Scalable, and Xeno Free Growth of Undifferentiated Human Embryonic Stem Cells

Technology / Case number: #16162
Anna Coclite / Amanda Diienno / Karen Gleason / Clark Colton
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Extra Cellular Matrix Proteins and Cancer

Technology / Case number: #15501JHR
Steven Carr / Richard Hynes / Alexandra Naba / Karl Clauser / Kenneth Tanabe
Technology Areas: Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Hydrogel Carriers for Monoclonal Antibody Crystals

Technology / Case number: #21065J
Patrick Doyle / Jeremy Schieferstein / Paul Reichert / Chakravarthy Narasimhan / Amir Erfani Khaneghahi
Technology Areas: Chemicals & Materials / Therapeutics
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Tricalcium Phosphate Binding Peptides and Proteins

Technology / Case number: #13913J
Luis Alvarez / Yadir Guerrero / Linda Stockdale / Jaime Rivera / Linda Griffith
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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  • Women's Health
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Cytosolically-Active Peroxidases as Reporters for Electron Microscopy

Technology / Case number: #15128
Jeffrey Martell / Alice Ting
Technology Areas: Diagnostics / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
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Nanoparticle Delivery of Adjuvant-Method of Preparation and Uses Thereof

Technology / Case number: #13344J
Frank Alexis / Pamela Basto / Ulrich Von Andrian / Elliot Moseman / Matteo Iannacone / Jinjun Shi / Elena Tonti / Robert Langer / Omid Farokhzad
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Methods for Cell Separation and Cytometry Based on Directed Cell Rolling on Patterned Substrates

Technology / Case number: #12899
Jeffrey Michael Karp / Seungpyo Hong / Rohit N Karnik / Ying Mei / Suman Bose / Robert Langer / Daniel Anderson
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Methods and Compositions of Matter for Activating Class I Histone Deacetylases (HDACs) for Treatment of Human Disease

Technology / Case number: #14951PJHQ
Li-Huei Tsai / Stephen Haggarty / Ling Pan / Debasis Patnaik
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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A Novel Method to Treat Myocardial Infarction and Other Tissue Damage Using Apolipoprotein D (apoD)

Technology / Case number: #15466
Kosuke Tsukamoto / Monty Krieger
Technology Areas: Biomaterials & Bioelectronics / Therapeutics
Impact Areas: Healthy Living
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Thiol-yne Mediated Synthesis of Multi-Tailed Lipids for siRNA Delivery

Technology / Case number: #15846
Kevin Love / Akinleye Alabi / Robert Langer / Daniel Anderson
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Novel Method for the Detection of Anticoagulants in Plasma and Whole Blood

Technology / Case number: #19252J
Galit H. Frydman / Pavan Bendapudi / James Fox / Charles Vanderburg / Ronald Tompkins / Mehmet Toner
Technology Areas: Diagnostics
Impact Areas: Healthy Living
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Therapeutic Protein Release From Degradable Layer-by-Layer Assembled Films for Sustained, Local Drug Delivery

Technology / Case number: #12642
Mara MacDonald / Paula Hammond
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Inhalable Nanosensors with Volatile Reporters for Rapid Pathogen Identification in Respiratory Infections

Technology / Case number: #20307HL
Leslie Chan / Melodi Anahtar / Rod Kunz / Sangeeta Bhatia
Technology Areas: Biotechnology / Chemicals & Materials / Diagnostics
Impact Areas: Healthy Living
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Reversible Covalent Modification for Improving Protein Delivery

Technology / Case number: #16581HQ
Li Tang / Darrell J Irvine
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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DNA Instructional Model

Technology / Case number: #17291
Bethany Lemanski / Kathleen Mead Vandiver / J. Kim Vandiver
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Self-Assembled (Poly-(L-Glutamic Acid-PEG-Drug)-PLGA Micelles for Multistage Nanoparticle Delivery System

Technology / Case number: #14877J
Cliff Wong / Dai Fukumura / Moungi G Bawendi / Rakesh K. Jain
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Develop New Lethal Mutagens for Viral Diseases

Technology / Case number: #16089
John M Essigmann / Deyu Li / Katherine Silvestre
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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