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Enhanced-Affinity Anti-ECM Nanobody-Cytokine Fusions and Their Applications

Exclusively Licensed Technology / Case number: #23602
Richard Hynes / Emi Lutz / Noor Momin / Noor Jailkhani / Karl Dane Wittrup
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living

Use of Expandable & Deformable Microspheres for Medical Applications

Exclusively Licensed Technology / Case number: #12143J
Elazer R Edelman / Rinaldo Schiffino / Surbhi Mahajan / Garry Figuly / Tarek Shazly / Michael Feldstein
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living

Determinants of Human Receptor Specificity of Influenza A Virus H2N2 Hemagglutinin

Exclusively Licensed Technology / Case number: #14302
Rahul Raman / Xiaoying Koh / Karthik Viswanathan / Aarthi Chandrasekaran / Ram Sasisekharan
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living

Microbial Engineering for the Production of Chemical and Pharmaceutical Products from Isoprenoid Pathway

Exclusively Licensed Technology, Tangible Property / Case number: #13905J
Gregory Stephanopoulos / Heng Phon Too / Parayil Ajikumar
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living

Method for Screening Libraries of Enzymes with Improved Catalytic Properties or Altered Substrate Specificity Using Microwells for the Spatial Separation of Cells Producing the Enzymes

Exclusively Licensed Technology / Case number: #12967WJ
Kerry Love / J. Christopher Love
Technology Areas: Biotechnology / Chemicals & Materials / Diagnostics / Therapeutics
Impact Areas: Healthy Living

Brushed Prodrugs and Uses Thereof

Exclusively Licensed Technology / Case number: #21834
Jeremiah A. Johnson / Hung Nguyen / Yivan Jiang
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living

Highly Potent Monofunctional Platinum (II) Anticancer Agents, cDACP (acriplatin) and cDPnCP (phenanthriplatin)

Non-Exclusively Licensed Technology / Case number: #14702
Stephen J Lippard / Ga Young Park
Technology Areas: Diagnostics / Therapeutics
Impact Areas: Healthy Living
License

Biomaterials for Enhanced Implant-Host Integration

Exclusively Licensed Technology / Case number: #22709HJQ
Christopher Chen / Michael Yang / Ritika Chaturvedi / Jan Baranski / Kelly Stevens / Sangeeta Bhatia
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Therapeutics
Impact Areas: Healthy Living, Advanced Materials

Nanoscale Imaging of Proteins and Nucleic Acids via Expansion Microscopy

Non-Exclusively Licensed Technology / Case number: #18127TEYJQ
Edward Stuart Boyden / Shahar Alon / Evan Daugharthy / Fei Chen / Asmamaw Wassie / George Church
Technology Areas: Biotechnology / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living
License

Novel RNA Modality for Translation in Eukaryotic Cells

Exclusively Licensed Technology / Case number: #19874Q
Daniel Anderson / Robert Wesselhoeft / Piotr Kowalski
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living

A Biosensor and Method Based on Magnetic Resonance Relaxometry

Exclusively Licensed Technology / Case number: #14651DE
Jongyoon Han / Lan Chen / Weng Kung Peng
Technology Areas: Biotechnology / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living

Magnetic Resonance Relaxometry (MRR) Measurement to Predict Chondrogenic Potential of Mesenchymal Stem Cells (MSCs)

Exclusively Licensed Technology / Case number: #24080DEJ
Jongyoon Han / Dahou Yang / Eng Lee / Yingnan Wu / Zheng Yang
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living

Body Fluid Resistant Tissue Glues

Exclusively Licensed Technology / Case number: #21933J
Xuanhe Zhao / Christoph Nabzdyk / Xinyu Mao / Hyunwoo Yuk
Technology Areas: Biomaterials & Bioelectronics / Therapeutics
Impact Areas: Healthy Living, Advanced Materials

Lipomer Nanoparticles for Highly Efficient SiRNA Delivery

Exclusively Licensed Technology / Case number: #14649
Robert Langer / James Dahlman / Avraham Schroeder / Christopher Levins / Daniel Anderson
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living

SAR of Bromodomain Inhibitor/Linker for Modulation of Release Profile of BET-BRUSH Prodrugs

Exclusively Licensed Technology / Case number: #20376
Jeremiah A. Johnson / Farrukh Vohidov
Technology Areas: Therapeutics
Impact Areas: Healthy Living

BioMimetics: Human Physiome on a Chip (6 month review)

Non-Exclusively Licensed Technology / Case number: #18509Q
Steven Robert Tannenbaum / Duncan Freake / Gaurav Rohatgi / Cynthia (Cindy) Stokes / Wen Li Chen / Mohan Bhushan / Murat Cirit / Collin Edington / Luis Soenksen Martinez / David L Trumper / Linda Griffith
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
License

Broad Neutralizing Antibodies to Groups 1 and 2 Influenza HA

Exclusively Licensed Technology / Case number: #15049
Ram Sasisekharan / Vidya Subramanian / Kannan Tharakaraman / Venkataramanan Soundararajan / Sasisekharan Raguram / Viswanathan Sasisekharan
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living

Modified Alginates for Islet Encapsulation and Diabetes Treatment

Exclusively Licensed Technology / Case number: #14528JQ
Robert Langer / Arturo Vegas / Kaitlin Bratlie / Minglin Ma / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Advanced Materials

Tomographic Phase Microscopy

Non-Exclusively Licensed Technology / Case number: #12615
Michael Feld / Wonshik Choi / Christopher Fang-Yen / Ramachandra Dasari
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
License

Swellable, Structurally Homogeneous Hydrogel for Expansion and Nanoscale Imaging of Biological Samples

Non-Exclusively Licensed Technology / Case number: #19849TE
Edward Stuart Boyden / Ruixuan Gao / Linyi Gao / Chih-Chieh (Jay) Yu
Technology Areas: Biotechnology / Chemicals & Materials / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living, Advanced Materials
License

The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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