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A Mitochondria Targeting Platinum(IV) Complex with Dual Cell Killing Modes

Technology / Case number: #13271
Stephen J Lippard / Shanta Dhar
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Flow Interference Lithography

Technology / Case number: #12865
Edwin Thomas / Ji-Hyun Jang / Dhananjay Dendukuri / Patrick Doyle / Chaitanya Ullal
Technology Areas: Biotechnology / Chemicals & Materials / Diagnostics
Impact Areas: Healthy Living
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Formulation of Polymeric Particles for Prostate Cancer Targeting

Technology / Case number: #12162J
Robert Langer / Stephen Zale / Benjamin Teply / Jianjun Cheng / Omid Farokhzad
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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DNA Repair Capacity Kit

Technology / Case number: #15137
Leona Hunter / Anthony Forget / Anwaar Ahmad / Isaac Chaim / Carrie Thompson / Zachary Nagel
Technology Areas: Biotechnology / Diagnostics
Impact Areas: Healthy Living
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Affinity-Based Detection of Ligand-Encoded Synthetic Biomarkers

Technology / Case number: #16292H
Sangeeta Bhatia / Andrew Warren / Kevin Lin / Gabriel Kwong / David Wood
Technology Areas: Biotechnology / Diagnostics
Impact Areas: Healthy Living
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Antigenically Intact Hemagglutinin in Circulating Avian and Swine Influenza Viruses and Potential for H3N2 Pandemic

Technology / Case number: #16225
Rahul Raman / Kannan Tharakaraman / Ram Sasisekharan
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Immune Pharmacytes: Nanoparticle-Modified Leukocytes for Immunotherapy

Technology / Case number: #13509H
Darrell J Irvine / Anna Bershteyn / Jae Hyun (James) Moon / Matthias Stephan
Technology Areas: Diagnostics / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Use of Gel Pads or Particles with Oil Isolation to Create Small Reaction Volumes

Technology / Case number: #16388
Patrick Doyle / Rathi Srinivas
Technology Areas: Biotechnology / Diagnostics
Impact Areas: Healthy Living
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Identification of Mitochondrial GABA Transporter

Technology / Case number: #26187
Matthew Vander Heiden / Samuel Block
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Metakaryocides for Treatment of Cancers and Other Diseases with Metakaryotic Stem Cells

Technology / Case number: #15279
William Thilly / Elena Gostjeva
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
License

Protein Retrosplicing Enabled by a Double Ligation Reaction

Technology / Case number: #15368
Bradley L. Pentelute / Rocco Policarpo / Jingjing Ling / Amy Rabideau / Xiaoli Liao
Technology Areas: Computer Science / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Engineered Probiotics for Urinary Cancer Diagnosis

Technology / Case number: #15881HJ
Sangeeta Bhatia / Jeff Hasty / Arthur Prindle / Tal Danino
Technology Areas: Biomaterials & Bioelectronics / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
License

Methods for Treating Polycystic Kidney Disease

Technology / Case number: #16389J
John M Essigmann / Stefan Somlo / Sorin Fedeles / Bogdan I Fedeles / Robert Croy
Technology Areas: Therapeutics
Impact Areas: Healthy Living
License

Single Wall Carbon Nanotubes as In Vivo Sensors

Technology / Case number: #16531
Michael S. Strano / Nicole Iverson / Thomas McNicholas / Nigel Reuel
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
License

Engineering DNA Assembly in Vivo and Knock Down of Gene Expression Using the Reverse Transcriptase Activity

Technology / Case number: #16593
Christopher Voigt / Johann Elbaz
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
License

Diminished Proteolytic Shedding of Receptor Tyrosine Kinases Mediates MEK Inhibitor Resistance in Triple-Negative Breast Cancer

Technology / Case number: #16742
Linda Griffith / Madeleine Oudin / Miles Miller / Aaron Meyer / Frank Gertler / Douglas Lauffenburger
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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  • Women's Health
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High Throughput Isolation of Antigen-Specific Antibodies and Cells

Technology / Case number: #16927J
Jongyoon Han / Galit Alter / Aniruddh Sarkar / Han Wei Hou
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
License

Salmochelin-Antibiotic Conjugates for Targeting Gram-Negative Pathogens

Technology / Case number: #16939
Elizabeth M. Nolan / Phoom Chairatana / Tengfei Zheng
Technology Areas: Therapeutics
Impact Areas: Healthy Living
License

Siderophore-Based Immunization Against Gram-Negative Bacteria

Technology / Case number: #16976J
Elizabeth M. Nolan / Araceli Perez-Lopez / Martina Corsi / Manuela Raffatellu / Phoom Chairatana
Technology Areas: Therapeutics
Impact Areas: Healthy Living
License

One-Step Protein Analysis Using Slanted Nanofilter Array

Technology / Case number: #17391
Jongyoon Han / Sung Ko
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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