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Peptide Nucleic Acid Functionalized Hydrogel Microneedles for Sampling and Detection of Interstitial Fluid Nucleic Acids

Technology / Case number: #21359HJ
Darrell J Irvine / Dana Al Sulaiman / Sylvain Ladame / Yin Hao Chang
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Development of a Platform to Noninvasively Image Car T Cells

Technology / Case number: #25905J
Michael Hemann / Julia Froese / Ali Salehi / Taha Rakhshandehroo / Jennifer Rowley / Mohammad Rashidian
Technology Areas: Biotechnology / Sensing & Imaging / Therapeutics
Impact Areas: Healthy Living
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FISHTALE- Fluorescent In Situ Hybridization of TAL Effectors

Technology / Case number: #19813TE
Edward Stuart Boyden / Nicholas Barry / Samuel Rodriques / Adam Marblestone
Technology Areas: Sensing & Imaging / Therapeutics
Impact Areas: Healthy Living
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RNA Degradation-based Toggle Switch

Technology / Case number: #21622
Ron Weiss / Noreen Wauford / Breanna DiAndreth
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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A Therapeutic Strategy for Rett Syndrome and Autism Spectrum Disorders

Technology / Case number: #12720WPJ
Rudolf Jaenisch / Emanuela Giacometti / Daniela Tropea / Nathan Wilson / Mriganka Sur
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Anti-Ebola Neutralizing Antibodies

Technology / Case number: #17334
Ram Sasisekharan / Devin Quinlan / Vidya Subramanian / Kannan Tharakaraman
Technology Areas: Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Artificially Engineered Protein Hydrogels to Mimic Nucleoporin Selective Gating

Technology / Case number: #17166
Bradley D. Olsen / Minkyu Kim
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Robocap

Technology / Case number: #24836J
Robert Langer / Amro Alshareef / Shriya Sruthi Srinivasan / Giovanni Traverso
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Boron-Containing Pharmacophore

Technology / Case number: #21111
Ronald T Raines / Brian Graham / Ian Windsor
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Production of Stable Non-Polyadenylated RNAs

Technology / Case number: #15860
Phillip Sharp / Jeremy Wilusz
Technology Areas: Biotechnology / Drug Delivery
Impact Areas: Healthy Living
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Compositions for Protein Labeling Using Lipoic Acid Ligases

Technology / Case number: #15299J
Alice Ting / David Baker / Florian Richter / Lucas Nivon / Daniel Liu
Technology Areas: Biotechnology / Diagnostics / Therapeutics
Impact Areas: Healthy Living
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Compact, Portable, Re-Configurable Unit for Making On-Demand Pharmaceutical Tablets

Technology / Case number: #19221
David Brancazio / Gregory Hammersmith / Juan Osorio Caicedo / Mohammad Azad / Allan S. Myerson
Technology Areas: Drug Delivery / Industrial Engineering & Automation
Impact Areas: Healthy Living
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Conformable Ultrasound Face Patch for Cavitation Enhanced Transdermal

Technology / Case number: #24824TE
Canan Dagdeviren
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Ionizable Lipid OF-02 and its Use in mRNA Delivery

Technology / Case number: #17733
Daniel Anderson / Rebecca McClellan / Kevin Kauffman / Owen Fenton / Joseph Dorkin
Technology Areas: Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living, Advanced Materials
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Enhanced Differentiation to Endodermal Derivatives with Modulated Oxygen Level

Technology / Case number: #15589
Clark Colton / Amanda Diienno / Jeffrey Millman
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Fusion Proteins As A Cause For ALS

Technology / Case number: #24280J
Ernest Fraenkel / Ricardo Pinto / Dadi Gao / Michael Talkowski / Allison Dilliott / Spencer Kim / Merit Cudkowicz / James Berry / Tiziana Petrozziello / Vakili Khashayar / Yogindra Raghav / Sali Farhan / Ghazaleh Sadri-Vakili
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Human Microbiome Clostridia-Derived Biosynthetic Enzymes/Pathways for the Biological Production of Natural and Non-Natural Fatty Acylated Compounds

Technology / Case number: #20961
Christopher Voigt / Fang-Yuan Chang
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living
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In Vitro and in Vivo Delivery of Complex Genetic Circuits up to 33kb Using Engineered HSV-1

Technology / Case number: #20746
Ron Weiss / Ross Jones / Jin Huh / Maria Hottelet Foley
Technology Areas: Diagnostics / Drug Delivery
Impact Areas: Healthy Living
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Phosphorylation-Based miRNA High Sensor

Technology / Case number: #19683
Ron Weiss / Ross Jones / Jin Huh
Technology Areas: Biotechnology / Diagnostics / Therapeutics
Impact Areas: Healthy Living
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A Signal Inverter Module for RNA Cleavers: Detecting and Evaluating miRNA, Ribozymes, and Ribonucleases

Technology / Case number: #19604
Ron Weiss / Breanna DiAndreth
Technology Areas: Biotechnology / Diagnostics / Therapeutics
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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