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An Approach for Enriching the Production of DNA Cargo Loaded AAV5 Capsids in Cells

Technology / Case number: #25585
Anthony Sinskey / John Joseph / Prasanna Srinivasan / Jacqueline Wolfrum / Rui Wen Ou / Stacy Springs / Richard D Braatz / Paul Barone
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Machine Learning-Guided Discovery of Nanoparticle Formulations Maximizing mRNA Transfection

Technology / Case number: #25890J
Giovanni Traverso / Taksim Ahmed / Hao Song / Xisha Huang / Simon Qu / Deepak Subramanian / Jonathan Woo / Alvin Chan / Joshua Bernstock / Ameya Kirtane
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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A Computational Method for Identifying the Biophysical Interactions that Determine Human T Cell Specificity from Structural Data and Primary Amino Acid Sequences

Technology / Case number: #26026J
Xingcheng Lin / Jason George / Ailun Wang / José Onuchic / Herbert Levine
Technology Areas: Computer Science / Therapeutics
Impact Areas: Healthy Living
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Mucin-Inspired Glycopolypeptides for Managing Microbial Infections

Technology / Case number: #26189J
Katharina Ribbeck / Jessica Kramer / Michaela Gold / Kelsey Wheeler
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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  • Women's Health
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CD80 is a Biomarker of p53 Activity and a Target for Cancer Therapy

Technology / Case number: #15386H
Tyler Jacks / Leah Schmidt / David Feldser
Technology Areas: Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Poly(B-Amino Alcohols), Their Preparation and Uses Thereof

Technology / Case number: #14035QJ
Robert Langer / Wendy Liu / Minglin Ma / Daniel Anderson
Technology Areas: Biomaterials & Bioelectronics / Chemicals & Materials
Impact Areas: Healthy Living
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Biodegradable Polyamine-Fatty Acid Derived Lipidoids for Drug Delivery

Technology / Case number: #16367
Daniel Anderson / Rebecca McClellan / Owen Fenton / Joseph Dorkin
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Valency Controlled Quantum Dots with Tunable Number of Biotin Binding Sites

Technology / Case number: #12606B
Moungi G Bawendi / Wenhao Liu / Mark Howarth / Alice Ting
Technology Areas: Biotechnology / Chemicals & Materials / Diagnostics / Electronics & Photonics / Therapeutics
Impact Areas: Healthy Living
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Methods and Compositions for Protein Labeling Using Lipoic Acid Ligases

Technology / Case number: #12773
Alice Ting / Marta Fernandez Suarez / Yoon-Aa Choi / Hemanta Baruah
Technology Areas: Biotechnology / Diagnostics / Therapeutics
Impact Areas: Healthy Living
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Self-Assembling Peptides Incorporating Modifications and Methods of Use Thereof

Technology / Case number: #13846XE
Shuguang Zhang / Yoshiyuki Kumada
Technology Areas: Biomaterials & Bioelectronics / Therapeutics
Impact Areas: Healthy Living
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A Mitochondria Targeting Platinum(IV) Complex with Dual Cell Killing Modes

Technology / Case number: #13271
Stephen J Lippard / Shanta Dhar
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Formulation of Polymeric Particles for Prostate Cancer Targeting

Technology / Case number: #12162J
Robert Langer / Stephen Zale / Benjamin Teply / Jianjun Cheng / Omid Farokhzad
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Wearable Monitor and Feedback Device for Knee Osteoarthritis

Technology / Case number: #17056TE
Hugh M Herr / Madeleine Abromowitz
Technology Areas: Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living
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Seizure Detection and Prediction Apparatus

Technology / Case number: #15454J
Anantha Chandrakasan / Muhammad Bin Altaf / Dina El-Damak / Long Yan / Jerald Yoo / Ali Shoeb
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Communication Systems
Impact Areas: Healthy Living
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Antigenically Intact Hemagglutinin in Circulating Avian and Swine Influenza Viruses and Potential for H3N2 Pandemic

Technology / Case number: #16225
Rahul Raman / Kannan Tharakaraman / Ram Sasisekharan
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Immune Pharmacytes: Nanoparticle-Modified Leukocytes for Immunotherapy

Technology / Case number: #13509H
Darrell J Irvine / Anna Bershteyn / Jae Hyun (James) Moon / Matthias Stephan
Technology Areas: Diagnostics / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Functional and Universal Surface Anchors Based on N-Heterocyclic Carbenes

Technology / Case number: #15855
Jeremiah A. Johnson / Aleksandr Zhukhovitskiy
Technology Areas: Biomaterials & Bioelectronics / Chemicals & Materials / Electronics & Photonics / Energy & Distribution
Impact Areas: Connected World, Advanced Materials
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Identification of Mitochondrial GABA Transporter

Technology / Case number: #26187
Matthew Vander Heiden / Samuel Block
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Initiated Plasma Enhanced Chemical Vapor Deposition

Technology / Case number: #14827
Karen Gleason / Anna Coclite
Technology Areas: Biomaterials & Bioelectronics / Chemicals & Materials
Impact Areas: Advanced Materials
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Metakaryocides for Treatment of Cancers and Other Diseases with Metakaryotic Stem Cells

Technology / Case number: #15279
William Thilly / Elena Gostjeva
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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