Method for Combined Classification of Fluorescent Biomarkers and Expert Clinical Annotations on Standard White Light Photographs

A human expert may initially label a white light image of teeth, and computer vision may initially label a filtered fluorescent image of the same teeth. Each label may indicate presence or absence of dental plaque at a pixel. The images may be registered. For each pixel of the registered images, a union label may be calculated, which is the union of the expert label and computer vision label. The union labels may be applied to the white light image. This process may be repeated to create a training set of union-labeled white light images. A classifier may be trained on this training set. Once trained, the classifier may classify a previously unseen white light image, by predicting union labels for that image. Alternatively, the items that are initially labeled may comprise images captured by two different imaging modalities, or may comprise different types of sensor measurements.