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Reprogram the Genome of M13 Phage for Vaccination and Immunotherapy Applications

Technology / Case number: #25169
Angela Belcher / Shengnan Huang
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Expression Constructs for One-Step Construction of Allogeneic CAR-NK Cells

Technology, Tangible Property / Case number: #26118J
Jianzhu Chen / Fuguo Liu / Rizwan Romee
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Connected World
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Using a Genetically Modified Human IPS Line to Screen for Drugs that Prevent or Treat Alzheimer's Disease

Technology / Case number: #26292P
Li-Huei Tsai / Masayuki Nakano / Matheus Victor / Leyla Akay / TaeHyun Kim
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Programmable Addition Via Site-Specific Targeting Elements (PASTE)

Technology / Case number: #22225
Omar Abudayyeh / Jonathan S. Gootenberg
Technology Areas: Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Discovery and Engineering of Novel Integrases for High-Efficiency Gene Integration

Technology / Case number: #23554
Omar Abudayyeh / Justin Lim / Lukas Villiger / Jonathan S. Gootenberg
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Oxygenating Reservoir for Culture Media in Microphysiological Systems

Technology / Case number: #25858
Linda Griffith / Matthew Johnson / Sydney Kim / Priyatanu Roy / David L Trumper
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Flow Cytometry with Mass Sensitive Readout

Technology / Case number: #12273J
Scott Manalis / Ken Babcock / Michel Godin / Thomas Burg
Technology Areas: Biotechnology / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living
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Raman Spectroscopy Based Sensitive and Specific Detection of Alternate Glycemic Markers, Glycated Hemoglobin (HbA1c) and Glycated Albumin for Longterm Diabetes Monitoring

Technology / Case number: #15295
Ramachandra Dasari / Jeon Woong Kang / Narahara Dingari / Ishan Barman
Technology Areas: Biotechnology / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living
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Multimodal and Network Phenotyping based on Single-Organelle In Situ Multiplexed Imaging

Technology / Case number: #25842
Mark Bathe / Reuven Falkovich
Technology Areas: Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Imidazole-Based Random Co-Polymer for Synthesis of Water Soluble Biocompatible Semiconductor Nanocrystals

Technology / Case number: #13877
Moungi G Bawendi / Peter Allen / Wenhao Liu / Numpon Insin
Technology Areas: Chemicals & Materials / Diagnostics / Electronics & Photonics
Impact Areas: Healthy Living
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Heterocycle-Modified Quinolines for Fluorescence-Based Protein Kinase Sensing

Technology / Case number: #13876
Barbara Imperiali / Juan Gonzalez Vera / Elvedin Lukovic
Technology Areas: Biotechnology / Diagnostics / Therapeutics
Impact Areas: Healthy Living
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An Information-Theoretic Approach for Analyzing Chromatin State Models

Technology / Case number: #17666
Manolis Kellis / Wouter Meuleman
Technology Areas: Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Transcriptional Engineering of Lactobacillus for Improved Lactic Acid Tolerance and Productivity at Low pH

Technology / Case number: #12783
Gregory Stephanopoulos / Daniel Klein-Marcuschamer
Technology Areas: Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Methods for Microbial Oil Overproduction via Amplification of the Biosynthetic and Sequestration Pathways Individually or in Combination

Technology / Case number: #15152
Gregory Stephanopoulos / Sagar Chakraborty / Mitchell Tai
Technology Areas: Biotechnology / Chemicals & Materials / Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Translocation of Non-Natural Chemical Entities Through Anthrax Protective Antigen Pore

Technology / Case number: #15639J
Bradley L. Pentelute / R. Collier / Gizem Akcay / Jingjing Ling / Amy Rabideau / Xiaoli Liao
Technology Areas: Computer Science / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Reversible and Ratiometric Sensing using Nanocrystals

Technology / Case number: #11693
Moungi G Bawendi / Rebecca Somers / Preston Snee / Daniel Nocera
Technology Areas: Biotechnology / Diagnostics / Electronics & Photonics / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Distinct Gene Systems Mediating Activity-Dependent Plasticity in Visual Cortex

Technology / Case number: #11841P
Mriganka Sur / Gabriel Kreiman / Daniela Tropea / Shayan Mukherjee / Alvin Lyckman
Technology Areas: Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Oscillating Cell Culture Bioreactor

Technology / Case number: #12301
Lisa Freed / Matteo Moretti / Robert Langer
Technology Areas: Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Glucose Valve and Other Metabolite Valves

Technology / Case number: #12369
Tae Moon / Kevin Solomon / Kristala L Jones Prather
Technology Areas: Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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CD80 is a Biomarker of p53 Activity and a Target for Cancer Therapy

Technology / Case number: #15386H
Tyler Jacks / Leah Schmidt / David Feldser
Technology Areas: Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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