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An Information-Theoretic Approach for Analyzing Chromatin State Models

Technology / Case number: #17666
Manolis Kellis / Wouter Meuleman
Technology Areas: Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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CD80 is a Biomarker of p53 Activity and a Target for Cancer Therapy

Technology / Case number: #15386H
Tyler Jacks / Leah Schmidt / David Feldser
Technology Areas: Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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1,2-Aminoalcohol Lipidoids (II)

Technology / Case number: #13661Q
Robert Langer / Kathryn Whitehead / Christopher Levins / Kevin Love / Kerry Mahon / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living
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Methods for Increasing Safety of Embryonic Stem Cells

Technology / Case number: #13769
Clark Colton / Jeffrey Millman
Technology Areas: Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Formulation of Polymeric Particles for Prostate Cancer Targeting

Technology / Case number: #12162J
Robert Langer / Stephen Zale / Benjamin Teply / Jianjun Cheng / Omid Farokhzad
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Immune Pharmacytes: Nanoparticle-Modified Leukocytes for Immunotherapy

Technology / Case number: #13509H
Darrell J Irvine / Anna Bershteyn / Jae Hyun (James) Moon / Matthias Stephan
Technology Areas: Diagnostics / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Methods for Enhanced Production of Cardiomyocytes From Embryonic Stem Cells

Technology / Case number: #12777
Clark Colton / Amanda Diienno / Jeffrey Millman / Daryl Powers
Technology Areas: Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Methods of Controlled Self-Renewal and Differentiation of Intestinal Stem Cells

Technology / Case number: #15728J
Robert Langer / Marc Succi / Xiaolei Yin / Jeffrey Michael Karp
Technology Areas: Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Microbial Production of 3,4-Dihydroxybutyrate (DHBA) and 3-Hydroxybutyrolactone (3-HBL) from Glucose

Technology / Case number: #14595
Kristala L Jones Prather / Himanshu Dhamankar / Collin Martin
Technology Areas: Chemicals & Materials / Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Protein Retrosplicing Enabled by a Double Ligation Reaction

Technology / Case number: #15368
Bradley L. Pentelute / Rocco Policarpo / Jingjing Ling / Amy Rabideau / Xiaoli Liao
Technology Areas: Computer Science / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Lithium-Ion Fiber Battery

Technology / Case number: #16676
Yoel Fink / Benjamin Grena
Technology Areas: Chemicals & Materials / Drug Delivery / Energy & Distribution
Impact Areas: Healthy Living, Advanced Materials
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Self-Assembling Peptides Incorporating Modifications and Methods of Use Thereof

Technology / Case number: #12321XE
Shuguang Zhang / Xiumei Wang / Fabrizio Gelain / Akihiro Horii
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Extended Transient Transfection by Repeated Delivery of RNA

Technology / Case number: #13415
Mehmet Yanik / Matthew Angel
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Surface Binding of Nanoparticles-Based Drug Delivery to Tissue

Technology / Case number: #15731
Alan Grodzinsky / Ambika Bajpayee / Cliff Wong / Rohit N Karnik / Moungi G Bawendi
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Nanoparticle Technology for Immune Response Against Small and Macromolecules-Method of Preparation and Uses Thereof

Technology / Case number: #13399J
Robert Langer / Elena Tonti / Jinjun Shi / Matteo Iannacone / Elliot Moseman / Ulrich Von Andrian / Pamela Basto / Frank Alexis / Omid Farokhzad
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Polymer Brush-Poly(glycoamidoamine)-Lipids (PGAL) and Uses Thereof

Technology / Case number: #15942
Robert Langer / Joseph Dorkin / Yizhou Dong / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living
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Engineering Microbes and Metabolic Pathways for the Production of Ethylene Glycol from Xylose, Glucose, Carbohydrates and Renewable Resources

Technology / Case number: #15064
Gregory Stephanopoulos / Jose Avalos / Marjan De Mey / Brian Pereira / Deepak Dugar
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Environmental Engineering
Impact Areas: Sustainable Future, Advanced Materials
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Brd4 as a Prognostic Indicator and Modulator of the Cell Response to DNA Damage

Technology / Case number: #15011
Michael Yaffe / Scott Floyd
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Vaccine Nanotechnology and Uses Thereof

Technology / Case number: #12788J
Robert Langer / Matteo Iannacone / Elliot Moseman / Tobias Junt / Ulrich Von Andrian / Pamela Basto / Liangfang Zhang / Frank Alexis / Omid Farokhzad
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Zwitterionic Dopamine Sulfonate Coated Iron Oxide Nanoparticles

Technology / Case number: #15322
Moungi G Bawendi / He Wei / Hee-Sun Han / Numpon Insin
Technology Areas: Chemicals & Materials / Drug Delivery / Sensing & Imaging
Impact Areas: Healthy Living, Advanced Materials
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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