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CD80 is a Biomarker of p53 Activity and a Target for Cancer Therapy

Technology / Case number: #15386H
David Feldser / Leah Schmidt / Tyler Jacks
Technology Areas: Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Biodegradable Polyamine-Fatty Acid Derived Lipidoids for Drug Delivery

Technology / Case number: #16367
Joseph Dorkin / Owen Fenton / Rebecca McClellan / Daniel Anderson
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Valency Controlled Quantum Dots with Tunable Number of Biotin Binding Sites

Technology / Case number: #12606B
Mark Howarth / Wenhao Liu / Moungi G Bawendi / Alice Ting
Technology Areas: Biotechnology / Chemicals & Materials / Diagnostics / Electronics & Photonics / Therapeutics
Impact Areas: Healthy Living
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Methods and Compositions for Protein Labeling Using Lipoic Acid Ligases

Technology / Case number: #12773
Hemanta Baruah / Yoon-Aa Choi / Marta Fernandez Suarez / Alice Ting
Technology Areas: Biotechnology / Diagnostics / Therapeutics
Impact Areas: Healthy Living
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Self-Assembling Peptides Incorporating Modifications and Methods of Use Thereof

Technology / Case number: #13846XE
Yoshiyuki Kumada / Shuguang Zhang
Technology Areas: Biomaterials & Bioelectronics / Therapeutics
Impact Areas: Healthy Living
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Polymer Base-Layer for Rapid Delamination of Multi-Layer Films From Microneedles

Technology / Case number: #15346H
Peter DeMuth / Younjin Min / Darrell J Irvine / Paula Hammond
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Methods for Increasing Safety of Embryonic Stem Cells

Technology / Case number: #13769
Jeffrey Millman / Clark Colton
Technology Areas: Drug Discovery and Research Tools
Impact Areas: Healthy Living
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A Mitochondria Targeting Platinum(IV) Complex with Dual Cell Killing Modes

Technology / Case number: #13271
Shanta Dhar / Stephen J Lippard
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Formulation of Polymeric Particles for Prostate Cancer Targeting

Technology / Case number: #12162J
Jianjun Cheng / Benjamin Teply / Stephen Zale / Robert Langer / Omid Farokhzad
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Antigenically Intact Hemagglutinin in Circulating Avian and Swine Influenza Viruses and Potential for H3N2 Pandemic

Technology / Case number: #16225
Kannan Tharakaraman / Rahul Raman / Ram Sasisekharan
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Immune Pharmacytes: Nanoparticle-Modified Leukocytes for Immunotherapy

Technology / Case number: #13509H
Matthias Stephan / Jae Hyun (James) Moon / Anna Bershteyn / Darrell J Irvine
Technology Areas: Diagnostics / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Methods for Enhanced Production of Cardiomyocytes From Embryonic Stem Cells

Technology / Case number: #12777
Daryl Powers / Jeffrey Millman / Amanda Diienno / Clark Colton
Technology Areas: Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Methods of Controlled Self-Renewal and Differentiation of Intestinal Stem Cells

Technology / Case number: #15728J
Jeffrey Michael Karp / Xiaolei Yin / Marc Succi / Robert Langer
Technology Areas: Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Salmochelin-Antibiotic Conjugates for Targeting Gram-Negative Pathogens

Technology / Case number: #16939
Tengfei Zheng / Phoom Chairatana / Elizabeth M. Nolan
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Siderophore-Based Immunization Against Gram-Negative Bacteria

Technology / Case number: #16976J
Phoom Chairatana / Manuela Raffatellu / Martina Corsi / Araceli Perez-Lopez / Elizabeth M. Nolan
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Methods for Treating Polycystic Kidney Disease

Technology / Case number: #16389J
John M Essigmann / Bogdan I Fedeles / Sorin Fedeles / Stefan Somlo / Robert Croy
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Engineering DNA Assembly in Vivo and Knock Down of Gene Expression Using the Reverse Transcriptase Activity

Technology / Case number: #16593
Christopher Voigt / Johann Elbaz
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Single Wall Carbon Nanotubes as In Vivo Sensors

Technology / Case number: #16531
Michael S. Strano / Nigel Reuel / Thomas McNicholas / Nicole Iverson
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Engineered Probiotics for Urinary Cancer Diagnosis

Technology / Case number: #15881HJ
Tal Danino / Arthur Prindle / Jeff Hasty / Sangeeta Bhatia
Technology Areas: Biomaterials & Bioelectronics / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Methodology to Deconvolve Metabolic Heterogeneity

Technology / Case number: #25787J
Yunping Qiu / Irwin Kurland / Lillian Delacruz / Alison Ringel
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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