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Multiplexed Specific Metalloprotease Activity Measurements

Technology / Case number: #19425DE
Miles Miller / Caroline Chopko Ahrens / Christi Cook / Steven Robert Tannenbaum / Ravindra Kodihalli / Evan Chiswick / Linda Griffith / Douglas Lauffenburger
Technology Areas: Biomaterials & Bioelectronics / Diagnostics / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Open-Ended, Dicer-Cleavable Concatemeric siRNA Generated by Rolling Circle Transcription

Technology / Case number: #18076
Connie Wu / Kevin Shopsowitz / Paula Hammond
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Development of Multi-Specific Antibody-Serum Albumin Fusion Proteins Targeting Multiple Human and Murine CXC (ELR+) Chemokines

Technology / Case number: #19355JQ
Alessandro Angelini / Andrew Luster / Karl Dane Wittrup
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Delivery of Preassembled Double-Stranded Short Interference RNA-Argonaute Protein Complexes for Enhanced RNAi-Based Therapeutics

Technology / Case number: #19340
Jiahe Li / Yanpu He / Wade Wang / Paula Hammond
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living, Uncharted Frontiers
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Discovery of Self-Labeling Miniproteins

Technology / Case number: #18742
Bradley L. Pentelute / Ethan Evans
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Uncharted Frontiers, Advanced Materials
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Sound Pressure Level Sensitive Passive Hearing Protector by Acoustic Metamaterials

Technology / Case number: #18005
Xuanlai Fang / Jun Xu
Technology Areas: Industrial Engineering & Automation
Impact Areas: Healthy Living
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MTFLOW - Software for Multielement Through-FLOW

Software / Case number: #7907
Technology Areas: Computer Science / Industrial Engineering & Automation
Impact Areas: Connected World, Advanced Materials
Labels
  • Expedited License

MISES - Software for Design and Analysis of Turbomachinery Blading

Software / Case number: #6570
Technology Areas: Computer Science / Industrial Engineering & Automation
Impact Areas: Uncharted Frontiers, Connected World
Labels
  • Expedited License

METRAN - Software for 13C-metabolic Flux Analysis

Software / Case number: #12397
Technology Areas: Biotechnology / Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living, Connected World
Labels
  • Expedited License

Structured DNA Conjugates

Technology / Case number: #18588
Mark Bathe / Sakul Ratanalert / Remi Veneziano / Tyson Shepherd / Hyungmin Jun
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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N/ASynergistic Tumor Treatment with IL-2, an Integrin-Binding-FC Fusion Protein, and a Cancer Vaccine

Technology / Case number: #18598HJ
Byron Kwan / Cary Opel / Kelly Moynihan / Darrell J Irvine / Jennifer Cochran / Karl Dane Wittrup
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
License

Printable Programmable Viscoelastic Materials

Technology / Case number: #18624
Daniela Rus / Robert MacCurdy / Jeffrey Lipton
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Industrial Engineering & Automation
Impact Areas: Advanced Materials
License

High Molecular Weight, Post-Translationally Modified Proteins Brushes Through Tyrosine Modification Chemistry

Technology / Case number: #17927
Bradley D. Olsen / Brian Seifried
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Additive Manufacturing of Vacuum Pumps

Technology / Case number: #19164J
Luis Fernando Velasquez-Garcia / Anthony Taylor
Technology Areas: Chemicals & Materials / Industrial Engineering & Automation
Impact Areas: Advanced Materials
Labels
  • Additive Manufacturing
License

Methods for Fabricating Low Cost 3D Printed Parts With Expanded Material Properties

Technology / Case number: #17894
Kumaran Kolandaivelu
Technology Areas: Biotechnology / Chemicals & Materials / Industrial Engineering & Automation
Impact Areas: Advanced Materials
License

Optimal Petroleum Fuels Blending Under Uncertainty

Technology / Case number: #17503
Yu Yang / Foivi Vayanou / Paul Barton
Technology Areas: Energy & Distribution / Industrial Engineering & Automation
Impact Areas: Climate Stabilization, Sustainable Future
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Highly Parallel Enzymatic DNA Synthesis Using Electrowetting Droplet Technology

Technology / Case number: #19620
Mark Bathe / Tyson Shepherd / James Banal / Joseph Berleant
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
License

Methods for Gene Delivery with Papillomaviruses

Technology / Case number: #21704
Omar Abudayyeh / Jonathan S. Gootenberg
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
License

Novel Peptidic Agents for Targeting Chemoresistant Anti-Apoptotic Mcl-1

Technology / Case number: #17695J
Amy Keating / Raheleh Rezaei Araghi / Greg Bird / Loren Walensky
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers, Advanced Materials
License

Removal of Ruthenium-Initiator from Brush-Arm Star Polymers (BASPs) via Core-to-Surface Ring-Opening Methathesis Polymerization (ROMP)

Technology / Case number: #19525
Jeremiah A. Johnson / Matthew Golder
Technology Areas: Biotechnology / Drug Delivery / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
License

The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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