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Nanoparticle Delivery of Adjuvant-Method of Preparation and Uses Thereof

Technology / Case number: #13344J
Robert Langer / Elena Tonti / Jinjun Shi / Matteo Iannacone / Elliot Moseman / Ulrich Von Andrian / Pamela Basto / Frank Alexis / Omid Farokhzad
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Methods for Cell Separation and Cytometry Based on Directed Cell Rolling on Patterned Substrates

Technology / Case number: #12899
Robert Langer / Suman Bose / Ying Mei / Rohit N Karnik / Seungpyo Hong / Jeffrey Michael Karp / Daniel Anderson
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Methods and Compositions of Matter for Activating Class I Histone Deacetylases (HDACs) for Treatment of Human Disease

Technology / Case number: #14951PJHQ
Li-Huei Tsai / Debasis Patnaik / Ling Pan / Stephen Haggarty
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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A Novel Method to Treat Myocardial Infarction and Other Tissue Damage Using Apolipoprotein D (apoD)

Technology / Case number: #15466
Monty Krieger / Kosuke Tsukamoto
Technology Areas: Biomaterials & Bioelectronics / Therapeutics
Impact Areas: Healthy Living
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Thiol-yne Mediated Synthesis of Multi-Tailed Lipids for siRNA Delivery

Technology / Case number: #15846
Robert Langer / Akinleye Alabi / Kevin Love / Daniel Anderson
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Composite Graphene Filtration Membranes

Technology / Case number: #15497J
Rohit N Karnik / Muataz Atieh / Tahar Laoui / Nicolas Hadjiconstantinou / Harold Au / Cameron Stewart / Michael Boutilier / Sean O'Hern
Technology Areas: Energy & Distribution / Environmental Engineering / Industrial Engineering & Automation
Impact Areas: Sustainable Future, Advanced Materials
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Reversible Covalent Modification for Improving Protein Delivery

Technology / Case number: #16581HQ
Darrell J Irvine / Li Tang
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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DNA Instructional Model

Technology / Case number: #17291
J. Kim Vandiver / Kathleen Mead Vandiver / Bethany Lemanski
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Self-Assembled (Poly-(L-Glutamic Acid-PEG-Drug)-PLGA Micelles for Multistage Nanoparticle Delivery System

Technology / Case number: #14877J
Moungi G Bawendi / Dai Fukumura / Cliff Wong / Rakesh K. Jain
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Develop New Lethal Mutagens for Viral Diseases

Technology / Case number: #16089
John M Essigmann / Katherine Silvestre / Deyu Li
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Genomic Insertion of Large Cargo with Engineered Retro Elements

Technology / Case number: #23248
Omar Abudayyeh / Justin Lim / Lukas Villiger / Jonathan S. Gootenberg
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Ligand-Inducible Post-Transcriptional Gene Regulation Using Protein-Binding RNA Aptamers

Technology / Case number: #13998J
Brian Belmont / Michael Marletta / Jacquin Niles / Stephen Goldfless
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Dendrimer and Peptide Based Excipients for the Attenuation of Protein Aggregation

Technology / Case number: #14184
Bernhardt Trout / Diwakar Shukla / Curtiss Schneider
Technology Areas: Chemicals & Materials / Industrial Engineering & Automation / Therapeutics
Impact Areas: Healthy Living
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Tissue Specific Delivery of Interfering RNA

Technology / Case number: #13947H
Sangeeta Bhatia / Yin Ren
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Peptide Nucleic Acid Functionalized Hydrogel Microneedles for Sampling and Detection of Interstitial Fluid Nucleic Acids

Technology / Case number: #21359HJ
Darrell J Irvine / Dana Al Sulaiman / Sylvain Ladame / Yin Hao Chang
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Development of a Platform to Noninvasively Image Car T Cells

Technology / Case number: #25905J
Michael Hemann / Julia Froese / Ali Salehi / Taha Rakhshandehroo / Jennifer Rowley / Mohammad Rashidian
Technology Areas: Biotechnology / Sensing & Imaging / Therapeutics
Impact Areas: Healthy Living
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Renewable Bio-Advantaged Plasticizer Generated by Reductive Coupling of Lignin Derived Aromatics

Technology / Case number: #25385J
Yuriy Roman / Zhiming Su / Caroline Hoyt / Jack Twilton / Shannon Stahl / Gregg Beckham
Technology Areas: Biotechnology / Chemicals & Materials / Environmental Engineering
Impact Areas: Sustainable Future, Advanced Materials
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FISHTALE- Fluorescent In Situ Hybridization of TAL Effectors

Technology / Case number: #19813TE
Edward Stuart Boyden / Nicholas Barry / Samuel Rodriques / Adam Marblestone
Technology Areas: Sensing & Imaging / Therapeutics
Impact Areas: Healthy Living
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RNA Degradation-based Toggle Switch

Technology / Case number: #21622
Ron Weiss / Noreen Wauford / Breanna DiAndreth
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Nanoengineered Hierarchical Polysulfone Membrane for Emulsion Separation

Technology / Case number: #15286
Kripa K Varanasi / Brian Solomon / Nasim Hyder
Technology Areas: Chemicals & Materials / Environmental Engineering
Impact Areas: Climate Stabilization
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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