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Methods for the Treatment of Trinucleotide Repeat Expansion Disorders Associated with FAN1 activity via Targeting of FAN1 Splice Site Inhibitory Sequences

Technology / Case number: #24829
Christopher Ng / David Housman
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Methods for Improving Cross-Ancestry Transferability in Predicting Polygenic Phenotypes from Genetic Variation

Technology / Case number: #24858
Manolis Kellis / Yosuke Tanigawa
Technology Areas: Drug Discovery and Research Tools
Impact Areas: Healthy Living
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RNAI-Based Method of Screening and Characterizing Drug Combinations

Technology / Case number: #19756
Michael Hemann / Justin Pritchard / Douglas Lauffenburger
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Transforming Silicate Containing Materials into Reactive Materials for CO2 Capture and Other Applications

Technology / Case number: #24493J
Matthew Kanan / Yogesh Surendranath / Wei Lun Toh / Rishi Agarwal / Benjamin Charnay / Yuxuan Chen / Joshua Rabinowitz
Technology Areas: Chemicals & Materials / Environmental Engineering
Impact Areas: Sustainable Future
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Novel Peptides Capable of Altering NK Cell Activity

Technology / Case number: #24321JQ
Michael Birnbaum / Brooke Huisman / Chiara Romagnani / Timo Ruckert
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Bioelectronic Devices to Support Transplanted Cells in Vivo for Encapsulated Cell Therapies

Technology / Case number: #23269J
Suman Bose / Robert Langer / Siddharth Krishnan / Matthew Bochenek / Nima Khatib / Daniel Anderson
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Energy & Distribution / Therapeutics
Impact Areas: Healthy Living
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Multisensory Gamma Stimulation Promotes Glymphatic Clearance of Amyloid

Technology / Case number: #25696PH
Li-Huei Tsai / Edward Boyden / Ping-Chieh Pao / Cheng-Yi Yang / Mitchell Murdock
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Maximizing Carbon Efficiency in CO2 Electrolyzers: Complete Conversion of Bicarbonate to Formate

Technology / Case number: #24910
Ju Li / Zhen Zhang / Zhichu Ren
Technology Areas: Energy & Distribution / Environmental Engineering
Impact Areas: Climate Stabilization, Sustainable Future
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Determining Phosphate Levels in Natural Water Using a Novel Electrochemical Measurement Device

Technology / Case number: #21708
Gee hoon Park / Ian Hunter
Technology Areas: Energy & Distribution / Environmental Engineering
Impact Areas: Sustainable Future
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Curbside-recyclable Products from Mono-material Polyethylene Fabrics With Polyethylene 3D Printed Features and Methods Thereof

Technology / Case number: #24436
Svetlana Boriskina / Volodymyr Korolovych / Leslie Yan / Duo Xu
Technology Areas: Chemicals & Materials / Environmental Engineering
Impact Areas: Sustainable Future, Advanced Materials
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Reconfigurable Precast Concrete Construction System for Buildings Designed through Algorithmic Engineering with Inventory Constraints

Technology / Case number: #25018
Caitlin Mueller / Inge Donovan / Jenna Schnitzler / Keith Lee / Yanjun Liu / Pitipat Wongsittikan
Technology Areas: Environmental Engineering / Industrial Engineering & Automation
Impact Areas: Sustainable Future
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Composite Anti-Fouling Coatings Designed via Full Spectral Hamaker Constant Minimization

Technology / Case number: #21606J
Michael Short / Max Carlson / Robert Simpson
Technology Areas: Chemicals & Materials / Energy & Distribution / Environmental Engineering
Impact Areas: Climate Stabilization, Sustainable Future
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Noise Recycling

Technology / Case number: #22102J
Kenneth Duffy / Amit Solomon / Alejandro Cohen / Muriel Medard
Technology Areas: Communication Systems / Computer Science / Environmental Engineering
Impact Areas: Sustainable Future, Connected World
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Dissolvable Microcarriers for Adherent Cell Culture

Technology / Case number: #22052JDE
Ee Xien Ng / Krystyn Van Vliet
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools
Impact Areas: Advanced Materials
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Methods of Enhancing the Survival of Introduced Genes and Organisms

Technology / Case number: #22105TE
Kevin Esvelt / Sarah Vitak
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Computationally-Optimized ACE2 Peptides for Competitive Interception of SARS-CoV-2

Technology / Case number: #22320XTE
Pranam Chatterjee / Raghava Manvith Ponnapati / Eyal Perry / Joseph Jacobson
Technology Areas: Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Zero-Crossing-Based Bio Engineered Sensor

Technology / Case number: #23713J
Timothy Lu / Carlo Giovanni Traverso / Phillip Nadeau / Christoph Winfried Johannes Steiger / Rabia Yazicigil Kirby / Maria Eugenia Inda / Adam Wentworth / Jenna Ahn / Qijun Liu / Miguel Jiminez
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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A Handheld Closed-Loop Automatic Insulin Delivery System

Technology / Case number: #22018J
Carlo Giovanni Traverso / Hen Wei Huang / Siheng You / Erin Raftery / Canchen Li
Technology Areas: Biotechnology / Communication Systems / Drug Delivery
Impact Areas: Healthy Living
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Genotype-Directed Local Delivery of Targeted Therapeutics at the Tumor Margin

Technology / Case number: #19863J
Carlo Giovanni Traverso / Ameya Kirtane / Daniel Cahill / Ganesh Shankar / Robert Langer
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Formulated, Biodegradable Polymeric Nanoparticles for Nucleic Acid Delivery to Non-Liver Targets

Technology / Case number: #19802
Kevin Kauffman / James Kaczmarek / Asha Patel / Luke Rhym / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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